DiabetesBio

Welcome to the March 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the March 2026 issue of Diabetes.
8:15 Kirk speaks with Matthew Merrins, PhD, Joseph F. Hoffman Professor of Cellular and Molecular Physiology at Yale School of Medicine. He is senior author on the article "Amino Acid Sensing by the α-Cell Mitochondrial Phosphoenolpyruvate Cycle Regulates Intracellular Ca2+Levels Without Affecting Glucagon Secretion," available at doi.org/10.2337/db25-0510.
29:25 Next, Darleen is joined by Noah Levi, an MD-PhD student in the group of Alejandro Caicedo, PhD, professor in the Division of Endocrinology, Diabetes and Metabolism, Department of Medicine at the University of Miami Miller School of Medicine. They are corresponding authors of the article "Activating Muscarinic Receptor Signaling in Intrapancreatic Neurons Is Required for Parasympathetic Cholinergic Control of Pancreatic Cell Function," available at doi.org/10.2337/db25-0604.
51:20 In the latest edition of "Sweet Talk," Kevin speaks with Mark Atkinson, PhD, about the American Diabetes Association's annual conference, Scientific Sessions. Atkinson is Eminent Scholar for Diabetes Research at the University of Florida and chair of the Scientific Sessions Programming Committee. More information about this year's Scientific Sessions, taking place June 5-8 in New Orleans, is available at professional.diabetes.org/scientific-sessions.
To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the February 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the February 2026 issue of Diabetes.
6:10 To discuss this issue's Paper of the Month, our hosts are joined by authors Christopher Wilson, PhD and Daniel J. Moore, MD, PhD, both of Vanderbilt University. Their article, "B Lymphocytes Impede Tregs to Erode Islet Tolerance in Type 1 Diabetes," is available for free at doi.org/10.2337/db25-0241.
37:05 Next, Darleen speaks with Bettina Mittendorfer, PhD. Dr. Mittendorfer is Senior Associate Dean for Research and Director of NextGen Precision Health, Clinical and Translational Science Unit at the University of Missouri and the lead author of "Effects of Marked Weight Loss Induced by Gastric Bypass Surgery or Low-Calorie Diet Alone on Postprandial Glucose Disposal in Type 2 Diabetes," available for free at doi.org/10.2337/db25-0737.
56:00 In the latest edition of "Sweet Talk," Kevin introduces Sir Stephen O'Rahilly, a clinical scientist at the University of Cambridge and past recipient of the American Diabetes Association's Banting Medal for Scientific Achievement. They discuss O'Rahilly's career, which reshaped scientists' understanding of metabolism and metabolic disease.
To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the January 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the January 2026 issue of Diabetes.
17:40 After sharing their predictions for the new year, our hosts are joined by Masaya Oshima, PhD, a contract researcher at Institut Cochin in Paris, France. He is the lead author on the January Paper of the Month, "Killing of Human β-Cells by CD8+ T Cells Triggers Inflammatory Paracrine Signaling and Neighboring β-Cell Dysfunction," available for free at doi.org/10.2337/db25-0473.
33:10 In the latest edition of "Sweet Talk," Kevin speaks with Sarah Stanley, MBBCh, PhD, an associate professor at the Icahn School of Medicine at Mount Sinai in New York and recipient of the American Diabetes Association's Pathway to Stop Diabetes Award. Her article, "Neural Regulation of Blood Glucose in Acute Stress: A Report on Research Supported by Pathway to Stop Diabetes," is available for free at doi.org/10.2337/dbi24-0051
To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the December 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the December 2025 issue of Diabetes.
13:10 After discussing their favorite interviews of the past two years, our hosts are joined by Bryan Bergman, PhD, a professor in the Division of Endocrinology, Metabolism, and Diabetes at the University of Colorado Anschutz Medical Campus. He is the corresponding author of "Combined Weight Loss and Exercise Training Alters Skeletal Muscle Subcellular Lipid Localization and Intermuscular Adipose Tissue Cellular Composition," a featured article in this month's issue. The article is available for free at doi.org/10.2337/db25-0492.
35:25 To discuss the latest Paper of the Month, our hosts are joined by authors Kathryn Walters, PhD, postdoctoral researcher at CU Anschutz, Roberto Castro-Gutierrez, PhD, a postdoctoral fellow at the University of California San Francisco, Neelanjan Mukherjee, PhD, Assistant Professor in the Department of Biochemistry and Molecular Genetics at the CU Anschutz, and Holger Russ, PhD, Associate Professor in the Department of Pharmacology and Therapeutics at the University of Florida. Their article, "Proteogenomic Discovery of Novel Open Reading Frames With HLA Immune Presentation on Human β-Cells," is available for free at doi.org/10.2337/db24-0527.
1:00:50 In the latest edition of "Sweet Talk," Kevin and Kirk explore how new technologies shape the ways we assess metabolism. They are joined by Alexander Banks, PhD, Director of the Energy Balance core facility at Beth Israel Deaconess Medical Center (BIDMC) at Harvard Medical School, Corey Holman, PhD, Technical Director of the Rodent Metabolic Phenotyping Core at the University of Pennsylvania, and Louise Lantier, PhD, Metabolic Pathophysiology Core Managing Director at Vanderbilt University Medical Center.
To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!

Welcome to the November 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the November 2025 issue of Diabetes.
6:00 In the first segment, our hosts are joined by Kaylia Reynolds, MS and Nora Franceschini, MD, MPH, FAHA, both of the Department of Epidemiology at the Gillings School of Global Public Health at the University of North Carolina. Their paper, "Diabetes Genetic Clusters and Clinical Outcomes in American Indians," is available for free at doi.org/10.2337/db25-0322.
20:40 To discuss the latest Paper of the Month, our hosts are joined by first author Stephanie K. Holm, a postdoctoral student in the Clemmensen group, and Christoffer Clemmensen, Associate Professor in the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen. Their paper, "Sustained Weight Loss With Combined LEAP2 and Semaglutide Treatment in Mice," is available for free at doi.org/10.2337/db24-1056.
38:15 In the latest edition of "Sweet Talk," Kevin and Kirk speak with Banting Medal recipient Jens Juul Holst, MD, DMSc, of the University of Copenhagen, whose work with incretin hormones laid the foundation for therapies now used around the world. His article, "Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture," is available for free at doi.org/10.2337/dbi21-0026.
To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don't forget to smash that "follow" button!