Front Burner

• Why is the U.K. rethinking puberty blockers?

  Today, an in-depth look at puberty blockers and their use on minors with gender dysphoria. These drugs have come under an enormous amount of scrutiny in recent years, with some questioning their benefits, safety and long-term impact.After banning the use of puberty blockers for gender treatment of people under 18, a new clinical trial in the U.K. aims to get to the bottom of those concerns.Azeen Ghorayshi is a science and gender reporter for the New York Times.She’ll parse through what we know and don’t know about the effects of blockers in minors, how this became a hugely divisive and politicized debate around the world, and whether this new trial could change our understanding.For transcripts of Front Burner, please visit: https://www.cbc.ca/radio/frontburner/transcripts

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• Hanukkah event shooting // Liberal majority watch

  First, the latest on the massacre at Bondi Beach in Australia. The mass shooting targeted the Jewish community on the first day of Hanukkah.We speak with Sean Tarek Goodwin, a reporter with ABC News, who was one of the first to arrive on the scene.Second, a surprise defection on Parliament Hill.Late last week, just hours after Parliament wrapped for the year, the Liberals welcomed another floor crosser into the party. With 171 seats, they are now just one MP away from holding a majority.Aaron Wherry is a senior writer with CBC’s Parliamentary bureau.He’s here to talk about all that, and look back at Prime Minister Carney’s first sitting.For transcripts of Front Burner, please visit: https://www.cbc.ca/radio/frontburner/transcripts

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• Is Trump’s MAGA movement in trouble? (FB Exclusive)

  ‘Make America Great Again' has been Donald Trump’s brand for a decade, riding the movement’s anti-elitist wave into the presidency and remaking the Republican Party. But cracks are now showing in the coalition, raising questions about Trump’s commitment to MAGA goals. One of his staunchest allies has become his loudest critic: Georgia congresswoman Marjorie Taylor Greene, who recently announced she would resign her seat next year. CBC’s Washington correspondents — Katie Simpson, Paul Hunter and Willy Lowry — discuss if Greene’s defection is a sign of growing discontent from Trump’s base.

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• Trump's vision for a new world order

  Every U.S. president releases a national security strategy document about a year into their term, but few have made as big a splash as Donald Trump's, earlier this month.The document formally spells out much of what we've come to expect from Trump's approach to foreign policy in his second term: political relationships are transactional, and American interests take priority above all else. The document also takes particular aim at Europe, and pledges explicit support for right-wing movements abroad.Bob Rae was, until recently, Canada's ambassador to the UN, following decades of political office including premier of Ontario. He reads between the document's lines and explains what it means for Canada — and asks how much of it is actually worth taking seriously.

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• Should everybody be taking Ozempic?

  It's estimated that as many as 10 per cent of adults in Canada use a GLP-1 type drug like Ozempic. The prescription medicine is used for type 2 diabetes management and increasingly prescribed off-label for weight loss. And this month, for the first time, the World Health Organization has conditionally recommended GLP-1 drugs for the long-term treatment of obesity.But while these drugs have been called a game-changing tool to manage a complex and stigmatized health condition, there’s also a lot of questions about the potential negative impact.With Ozempic’s patent set to expire soon in Canada, and more affordable generic options about to hit the market, a lot more people you know could end up on a weight-loss drug.Today we bring you the rise and risks of GLP-1s with help from Dylan Scott. He is a Senior Correspondent at Vox who covers health.For transcripts of Front Burner, please visit: https://www.cbc.ca/radio/frontburner/transcripts

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