Hardiness with Dr Paul Taylor

Dr Greg Eckel joins Dr Paul Taylor to discuss brain health, neurodegeneration and the possibility of brain repair. Greg shares how his wife’s rapid decline from dementia shaped his work and led him to develop the ECHO protocol. They explore potential contributors to brain health, including metabolic and gut health, inflammation, trauma and environmental factors, as well as emerging approaches involving light, sound and other therapies. They also discuss practical foundations such as exercise, sleep, nutrition and blood-sugar balance.
Key takeaways
Look beyond symptoms to possible drivers. Greg describes a “detect, then correct” approach, considering factors such as infections, environmental exposures and physical or emotional trauma. He emphasises that care should be tailored to the individual.
Brain health is connected to whole-body health. The conversation highlights the gut–brain connection, sleep, blood flow, metabolic health and inflammation as areas worth discussing with a qualified clinician.
Build the basics first. Regular exercise, restorative and consistent sleep, hydration, time outdoors and nutritious food are presented as foundations—not extras to skip in search of a quick fix.
Movement may support brain function. They discuss exercise, coordination and fast-twitch activity in relation to neuroplasticity and brain-derived growth factors.
Personalise nutrition and supplements. Paul discuss blood-sugar responses, omega-3s, magnesium, glutathione, plasmalogens and creatine, while stressing the value of individual assessment and medical guidance.
Emerging therapies need careful context. Light-based therapies, sound and CO₂-tolerance training come up as areas of interest; the episode distinguishes these discussions from established, universal recommendations.
A diagnosis or genetic risk isn’t the whole story. Greg’s perspective is that risk factors don’t necessarily determine an individual’s future, and it’s worth seeking appropriate assessment and support rather than giving up hope.

Time Stamps
1:18 The personal experience that redirected Eckel’s work
8:42 Misfolded proteins and the questions behind his neuroregeneration work
11:13 Mitochondria, sound and light
18:15 Photobiomodulation and the gut–brain connection in Parkinson’s
24:17 A “detect, then correct” approach and possible contributing factors
27:28 The ECHO protocol and combining different therapies
34:05 Neuroplasticity and neurogenesis
37:32 Exercise, brain-derived growth factors and fast-twitch muscle fibres
42:22 CO₂-tolerance breathing and brain circulation
44:38 Everyday foundations: blood-sugar balance, sleep, hydration and exercise
50:01 Trauma and its possible role in health
52:44 Hormones, genetic testing and personalised care
55:12 Omega-3s, magnesium, glutathione and plasmalogens
58:19 Post-viral effects and a discussion of the evidence
1:01:04 Glutathione and laser therapy
1:04:41 Creatine and brain health
1:06:08 Eckel’s view on whether the brain can regenerate

Resources
Books: Defying Parkinson’s
Shake It Off
Website: https://brainregen.com/
Website: https://bvital.com/
LinkedIn: https://www.linkedin.com/in/drgregeckel/
Instagram: https://www.instagram.com/drgreckel/?hl=en
Facebook: https://www.facebook.com/thebrainregen/
YouTube: https://www.youtube.com/channel/UCT2WJiLU_4BcbAKy-Z-4Epg

This episode is for general information, not personal medical advice. Talk with a qualified healthcare professional before changing treatment or starting supplements.
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Viktor Frankl wrote that the last of the human freedoms is “to choose one’s attitude in any given set of circumstances.” But when we're going through challenges, our emotions show up automatically, so what can we actually choose?
In this episode, Carly draws on Frankl’s Man’s Search for Meaning and Morita Therapy to explore what choosing our attitude looks like in practice. We can’t choose our first reaction. We can choose what we do next.
Carly is a counsellor and coach who specialises in building psychological hardiness, which is the ability to navigate challenge, stay engaged, and take meaningful action under pressure. Her work integrates modern psychology with Eastern and Stoic approaches, helping people build resilience, live with purpose, and respond to life’s challenges with greater clarity, courage and steadiness.
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In this episode, Dr Paul Taylor talks with integrative practitioner Dr Christobelle Yeoh about protecting cognitive health. They start with the rise of early cognitive decline, brain fog and stress, including during menopause. Dr Yeoh's central idea is that thinking depends on the body. Cognition rests on the lower-order systems that feed the brainstem: the gut, vascular tone, blood chemistry, breathing and the cranial nerves that read signals of safety. They explain how chronic stress and the brain's constant threat prediction affect it. They also cover why top-down approaches like CBT work best alongside bottom-up, body-based ones. The second half is practical. They look at common mismatches and what to do about them: get morning sunlight and keep a circadian rhythm, eat at regular times in daylight hours and prioritise protein and whole foods, and fix the basics before relying on supplements such as DHA, creatine and ubiquinol. They also cover CO₂-tolerance breathing, and movement that challenges balance and coordination to support neuroplasticity.
Key takeaways
Brain and body are not separate. Cognition depends on the health of the body's regulation systems.
Get outside for morning light soon after waking, and top up with light through the day.
Eat in daylight hours, include protein early, favour seasonal whole foods, and cut ultra-processed food.
Sort out the basics (light, food, sleep, hydration) before relying on supplements.
Combine top-down tools like CBT and ACT with bottom-up work like breathing, movement and gut health.
Choose movement that challenges balance and coordination, such as boxing combinations, dancing or crawling.
Start gently with breathwork. CO₂ tolerance practice is a safe place to begin, and cathartic breathwork needs guidance.
Time Stamps
0:59 Why cognitive health matters, with dementia now overtaking cardiovascular disease in Australia 1:34 What's going on: brain fog, early cognitive decline (MCI), and stress in menopause 4:02 Is getting more forgetful in your 40s, 50s and 60s a warning sign? 5:35 Reframing cognition as an emergent property of whole-system regulation 10:52 Chronic stress, the brain as a prediction engine, and early-life influences 17:20 Five key inputs to the brainstem: cranial nerves, gut, vascular tone, blood pH/redox, and breathing 21:59 Threat vs challenge stress appraisal, and cortisol vs adrenaline 24:48 Top-down (CBT, ACT) and bottom-up (body-based) approaches, and neuroplasticity 27:23 Functional brain networks, and why complex, cross-body movement matters 31:52 The big mismatches: circadian biology, supplements before fundamentals, cell membrane and bioelectricity, CO₂ tolerance, and psychology without physiology 40:31 Circadian basics: morning sunlight, "clocking in" with the sun, ditching sunglasses 43:30 Red and near-infrared light, and light-based therapy for neurodegenerative conditions 47:07 Food timing, protein and the protein leverage idea, seasonal eating, leptin and insulin resistance 51:54 Supplements: DHA, phospholipids, organ meats and liver capsules, electrolytes and minerals 54:09 Creatine and hydration, including the dehydration and cortisol study 57:14 Ubiquinol: dosing and its role in the electron transport chain 58:31 Urolithin A, B vitamins, and matching supplements to the person 1:00:12 Breathing: CO₂ tolerance and Buteyko-style training vs cathartic and holotropic breathwork 1:05:23 Psychology–physiology mismatch: somatic work, vitamin D, creatine and psychotherapy
Mentioned in this episode
Dr Dale Bredesen's work on reversing cognitive decline
UCLA Health: news release on the original 2014 study. The paper was “Reversal of cognitive decline: A novel therapeutic program” (UCLA/Buck Institute, 2014).
ScienceDaily: the 2016 follow-up study. It used quantitative MRI and neuropsychological testing before and after the program, following a protocol called ‘metabolic enhancement for neurodegeneration’.
Dr Stephen Porges (polyvagal theory and neuroception)
stephenporges.com: official site and timeline. The first paper describing the theory was Porges (1995), “Orienting in a defensive world,” published in Psychophysiology.
Prof. Mark Seery (challenge and threat appraisal)
Seery’s lab publications, University at Buffalo. The two key papers are Seery (2013), “The biopsychosocial model of challenge and threat: Using the heart to measure the mind,” and Seery (2011), “Challenge or threat? Cardiovascular indexes of resilience and vulnerability to potential stress in humans”
Dr Konstantin Buteyko and Patrick McKeown (CO₂ tolerance breathing)
Oxygen Advantage: how to measure your BOLT score
Oxygen Advantage: McKeown on breath-holding and the science behind it
Buteyko Clinic International podcast. McKeown founded the clinic in 2002
Dr Rosalba Courtney (breath and healing)
rosalbacourtney.com
The Human Connectome Project
humanconnectome.org
Previous episode with Dr Yeoh on mitochondria
Omny – Part 1 - Why You Need To Be A MITOchondriac Part 1 with Dr. Christabelle Yeoh
Omny – Part 2 - Why You Need to be A MITOchondriac Part 2 with Dr. Christabelle Yeoh
Resourses:
Next Practice Genbiome, Sydney (genbiome.nextpracticehealth.com)
Mitocore, Sydney (mitocore.com.au)
This episode is for general education and isn't personal medical advice. Speak with a qualified practitioner before changing your health routine or starting supplements.
See omnystudio.com/listener for privacy information.

See omnystudio.com/listener for privacy information.