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Manifold

Steve Hsu
Manifold
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168 episodes

  • Manifold

    Iran, AI, and the Third World War (Crossover with Seeking Truth From Facts Podcast)

    30/07/2026 | 52 mins.
    This is a crossover episode with Alf Beckinsale, an Oxford University student who hosts the Seeking Truth From Facts podcast. The main topics are the US-Iran conflict, geopolitics, and US-China AI competition.
    Chapter Markers:

    (00:00) - Introduction

    (02:33) - No Off Ramp in Gulf

    (04:11) - Missile Stockpile Crisis

    (06:46) - Oil Shock and Reserves

    (14:07) - Israel Stays Out

    (29:34) - China Frontier AI Surge

    (43:25) - World War and Nukes


    Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

    Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. 

    Mechanize is hiring! 
    https://mechanize.work/b/hsu 

    Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. 

    For example: 

    Research Engineer, Alignment: Build evals that test for misaligned model behaviors  $500K salary 

    Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve  $300K salary 

    Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
  • Manifold

    State of AI, Summer 2026 – #116

    16/07/2026 | 51 mins.
    Steve discusses the state of AI in summer 2026. Topics covered include: AI in math and theoretical physics, Recursive Self-Improvement, Agent swarms and tokenomics, IPOs and US-China competition, documentary film Machine God.
    Machine God trailer: https://www.youtube.com/watch?v=5RSv3wmDIpY
    Theoretical Physics with Generative AI: https://stevehsu.substack.com/p/theoretical-physics-with-generative
    Chapter Markers:

    (00:00) - State of AI, Summer 2026

    (02:39) - AI in Math Physics

    (13:54) - Recursive Self-Improvement

    (21:08) - DeepSeek Hyperconnections

    (29:42) - Agent Swarms and Tokenomics

    (43:26) - Machine God Documentary


    Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

    Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. 

    Mechanize is hiring! 
    https://mechanize.work/b/hsu 

    Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. 

    For example: 

    Research Engineer, Alignment: Build evals that test for misaligned model behaviors  $500K salary 

    Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve  $300K salary 

    Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
  • Manifold

    Beff Jezos and Effective Accelerationism: Machine God of Loving Grace

    02/07/2026 | 1h 40 mins.
    Beff Jezos (Guillaume Verdon) is a Canadian physicist, quantum computing researcher, and tech entrepreneur. He is best known as the founder of the Effective Accelerationism (e/acc) movement.

    This interview was recorded in collaboration with John Greer and Lei Huang for the documentary film Machine God.

    John Greer: https://www.johncgreer.com/

    Chapter Markers:

    (00:00) - Meet Beff Jezos

    (01:56) - Hyperstition vs AI Doom

    (21:29) - Accelerate or Die

    (37:51) - Scaling Intelligence Upside

    (40:26) - Doomers Power Centralization

    (47:17) - EAC Physics Framework

    (01:10:10) - Debating Doom Narratives

    (01:16:13) - Beff Jezos Origin Story

    (01:28:06) - Pause Debate and Rapid Fire


    Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

    Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. 

    Mechanize is hiring! 
    https://mechanize.work/b/hsu 

    Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. 

    For example: 

    Research Engineer, Alignment: Build evals that test for misaligned model behaviors  $500K salary 

    Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve  $300K salary 

    Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
  • Manifold

    Razib Khan at Manifest 2026: Genetic Discoveries, AI, and Academia – #114

    18/06/2026 | 1h 20 mins.
    This episode was recorded live at Manifest 2026. Razib Khan is a prominent writer, population geneticist, and podcaster. He is best known for his extensive deep-dives into human evolutionary history, consumer genomics, culture, and ancient DNA. 
    https://x.com/razibkhan
    https://x.com/razibkhan?lang=en
    Chapter Markers:

    (00:00) - Razib Khan at Manifest 2026: Genetic Discoveries, AI, and Academia

    (01:18) - Manifest Q&A Kickoff

    (02:43) - Yamnaya: Ancient DNA Mysteries

    (15:01) - Yamnaya: Y Chromosome Conquests

    (22:10) - Embryo Screening and AI

    (42:15) - Conformity and Tenure

    (46:34) - Academia: Reforms

    (53:55) - Academia: Ideological Capture and Funding

    (58:19) - Controversies and Closing Q&A


    Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

    Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. 

    Mechanize is hiring! 
    https://mechanize.work/b/hsu 

    Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. 

    For example: 

    Research Engineer, Alignment: Build evals that test for misaligned model behaviors  $500K salary 

    Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve  $300K salary 

    Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
  • Manifold

    Letter from Beijing 2: Tsinghua University – #113

    04/06/2026 | 1h 21 mins.
    This special episode was recorded at Tsinghua University in Beijing, generally regarded as the top university in China. Our guests are 3 Americans studying and working at Tsinghua: Gabriel (undergrad), Justin (PhD student in AI), and Alex (Professor in AI research). Topics discussed include: Tsinghua University and elite human capital, AI in China, US-China competition, and the flow of human capital between the US and China

    Han Feizi, columnist at Asia Times and the guest from the previous "Letter from Beijing" episode, is also in the room. Letter from Beijing with Han Feizi: https://www.manifold1.com/episodes/letter-from-beijing-with-han-feizi-72

    Chapter Markers:

    (00:00) - Welcome to Tsinghua University

    (02:47) - Gabriel’s Undergrad Journey

    (12:35) - Justin’s PhD

    (25:10) - Professor Alex on AI and Rankings

    (42:51) - Second Chances and Status Signals

    (46:48) - China’s Exam Ladder Explained

    (50:20) - Infrastructure and Tech Competition

    (01:17:18) - Semiconductors, EUV, and Wrap Up


    Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

    Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. 

    Mechanize is hiring! 
    https://mechanize.work/b/hsu 

    Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. 

    For example: 

    Research Engineer, Alignment: Build evals that test for misaligned model behaviors  $500K salary 

    Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve  $300K salary 

    Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
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About Manifold
Steve Hsu is Professor of Theoretical Physics and Computational Mathematics, Science, and Engineering at Michigan State University. Join him for wide-ranging conversations with leading writers, scientists, technologists, academics, entrepreneurs, investors, and more.
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