PodcastsAlternative HealthPushing The Limits

Pushing The Limits

Lisa Tamati
Pushing The Limits
Latest episode

427 episodes

  • Pushing The Limits

    Your Immune System Is Aging Faster Than You Are

    05/07/2026 | 39 mins.
    Your Immune Age Is Lying To You. Here's How To Read Your Blood And Fix It.
    How old is your immune system, really?
    It's probably not the same age as you are — and that gap may be the single biggest hidden driver of how well you age, how fast you recover, and how long you stay healthy. In this episode I break down what actually happens to your immune system as the years tick over — immunosenescence (the immune system getting weaker) and inflammaging (the silent, smouldering inflammation that never switches off) — and why almost every disease of ageing sits somewhere on that spectrum.
    Then I get practical. I'll show you how to measure your immune age from a standard blood test you can get anywhere in the world, using seven scientifically validated ratios (NLR, PLR, MLR, LMR, SII, PIV and ELR) synthesised into a single Immune Resilience Index. We cover the cutting-edge science from Dr David Furman's 1000 Immunomes Project and the iAge inflammatory clock, the TRIIM and TRIIM-X thymus-regeneration trials, the gut-immune connection (70% of your immune cells live in your gut), the cytokines of ageing (IL-6, TNF-alpha, IL-1 beta, NF-kB and IL-10), and how our Re:juvenate Pro formulation was built to target exactly these pathways. If you want to stop guessing and start tracking the system that runs your healthspan, this one's for you
    RELATED EPISODES — WATCH THESE NEXT
    Dr David Furman | The 1000 Immunomes Project and the inflammatory clock of aging: https://www.youtube.com/watch?v=HFOSqEY7CNY
    Dr Rod Claycomb | Colostrum, immune proteins and immune resilience: https://www.youtube.com/watch?v=VyOfcx9gvbE
    Aevum Labs panel | Peter Lehrke, medical herbalist Mike Eyres and Dr Rod Claycomb: https://www.youtube.com/watch?v=EstwHB3p3nI
    Dr Elizabeth Yurth | Immune aging and how to slow it: https://www.youtube.com/watch?v=h_-_rFXcBIA
    THE SCIENCE + RE:JUVENATE PRO Re:juvenate Pro at Aevum Labs: https://aevumlabs.co.nz/products/re-juvenate Aevum Labs: https://www.aevumlabs.co.nz
    🌐 Website: https://www.lisatamati.com
    🛒 Supplements: https://shop.lisatamati.com
    🎙️ Podcast: https://www.lisatamati.com/podcast
    📧 Contact: support@lisatamati.com
  • Pushing The Limits

    Professor Julia Rucklidge: Micronutrients, Mental Health and Why the RDAs Are Broken

    12/06/2026 | 1h 7 mins.
    The link between micronutrients and mental health is one of the most overlooked stories in modern medicine, and Professor Julia Rucklidge has spent more than two decades proving it matters. In this episode of Pushing the Limits, she shares the research on micronutrients and mental health that has challenged psychiatry's drug-first model, showing that broad-spectrum vitamins and minerals can treat ADHD, depression and anxiety, often as effectively as medication and without the side effects. If you have ever wondered how deeply micronutrients and mental health are connected, this conversation will change how you think about your brain, your mood and the food you eat every day.
    Professor Julia Rucklidge is a clinical psychologist at the University of Canterbury and Director of Te Puna Toiora, the Mental Health and Nutrition Research Lab. She is co-author, with Bonnie Kaplan, of The Better Brain, and her work has been published in leading psychiatry journals and viewed by millions through her TEDx talk. She came into this field as a sceptic, trained to believe that nutrition was irrelevant to the brain, and changed her mind only when the evidence became impossible to ignore.
    In this conversation, Julia explains what her clinical trials actually found, and why 60 to 80 percent of people respond to a broad-spectrum approach once you move past the noise of a blinded study. We talk about why feeding the whole system beats chasing a single nutrient, what the biomarkers reveal about inflammation, methylation and the microbiome, and why the RDAs were never designed to support an optimally functioning brain. She makes the case that the recommended daily allowances we rely on were built to prevent deficiency diseases, not to help the brain thrive, and that this gap matters enormously for anyone struggling with their mental health.
    We also explore the bigger forces at play: depleted soils and what modern agriculture has done to the nutrient density of our food, the rise of ultra-processed food and why Julia calls it the cigarette of the twenty-first century, and the antidepressant withdrawal that so many people are never warned about. She shares her frustration with New Zealand's outdated supplement regulations, where a product can be effectively banned for containing a fraction too much of a nutrient, and a distributor can be threatened with serious penalties for selling something that genuinely works.
    Most of all, this is a hopeful conversation. It is about taking back control of your health through the food on your plate, understanding the real connection between what you eat and how you feel, and recognising that small, consistent changes can have a profound effect on the brain. Whether you are a parent navigating a child's behaviour, someone managing your own mental health, or simply curious about the science of nutrition and the brain, this episode will give you a new lens on what is possible.
    If you have ever been told that nutrition is irrelevant to your brain, this episode is for you.
    Resources and mentions:
    The Better Brain by Bonnie Kaplan and Julia Rucklidge
    What Your Food Ate by David Montgomery and Anne Biklé
    Te Puna Toiora, Mental Health and Nutrition Research Lab, University of Canterbury
    Biography: 
     




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    Claude responded: Professor Julia Rucklidge is a clinical psychologist at the University of Canterbury and Director of Te Puna Toiora, the Mental Health and Nutrition Research L…
    div]:bg-bg-000/50 [&_pre>div]:border-0.5 [&_pre>div]:border-border-400 [&_.ignore-pre-bg>div]:bg-transparent [&_.standard-markdown_:is(p,blockquote,h1,h2,h3,h4,h5,h6)]:pl-2 [&_.standard-markdown_:is(p,blockquote,ul,ol,h1,h2,h3,h4,h5,h6)]:pr-8 [&_.progressive-markdown_:is(p,blockquote,h1,h2,h3,h4,h5,h6)]:pl-2 [&_.progressive-markdown_:is(p,blockquote,ul,ol,h1,h2,h3,h4,h5,h6)]:pr-8"> _*]:min-w-0 gap-3 standard-markdown"> Professor Julia Rucklidge is a clinical psychologist at the University of Canterbury and Director of Te Puna Toiora, the Mental Health and Nutrition Research Lab. One of the world's leading researchers in nutritional psychiatry, she has spent more than two decades running placebo-controlled trials showing that broad-spectrum micronutrients can treat ADHD, depression, anxiety and stress, often as effectively as medication and without the side effects. She is co-author, with Bonnie Kaplan, of The Better Brain, and her TEDx talk on nutrition and mental health has been viewed millions of times. Based in Christchurch, New Zealand, she is on a mission to put nutrition where she argues it belongs: as a serious, evidence-based part of how we treat and prevent mental illness.
  • Pushing The Limits

    R3HBG: The Bioidentical Ketone That Bypasses the Liver | Mike Chesne, Tecton Founder

    30/05/2026 | 1h 40 mins.
    What if there was an exogenous ketone that didn't go through the liver, didn't cause the GI distress of other ketones, and delivered bioidentical BHB directly to your cells?
    In this episode, Lisa sits down with Mike Chesne, founder of Tecton and retired US Army Special Forces combat medic, who spent 25 years in special operations before developing R3HBG — a patented ketone molecule that's categorically different from everything else on the market.
    Mike's journey from battlefield medicine to biotech is extraordinary. After suffering multiple traumatic brain injuries from IED blasts during nearly three years of combat, he went through brain injury rehabilitation and discovered the neuroprotective potential of ketones. He asked one question that changed everything: "If I had been in ketosis when I got blown up, how much better would my outcome have been?"
    That question led him to Oxford University, to Dr Kieran Clarke's lab, and eventually to designing his own molecule — drawing it on a napkin and spending over a decade turning it into a manufactured, FDA-reviewed product.
    In this deep-dive episode we cover:
    Mike's military career and the brain injuries that changed his path
    The DARPA project that spent $10 million searching for a supplement to boost performance and cognition by 30%
    Why the brain in Alzheimer's and TBI can't access glucose but can still take up ketones
    R3HBG explained: how lipase (not alcohol dehydrogenase) breaks it down, and why that matters
    The differences between BHB salts, R-1,3-butanediol, the original ketone ester, and R3HBG
    The NLRP3 inflammasome and how BHB blocks the inflammatory cascade driving neurodegeneration
    HDAC inhibition and how BHB switches on your body's own antioxidant and longevity genes
    NDI #1354 and what FDA New Dietary Ingredient acceptance means
    The GLP-1 agonist connection for weight management and metabolic health
    Therapeutic dosing for cognition, endurance, and recovery
    Mike's vision to license R3HBG to every ketone company willing to use it
    Lisa's experience using ketones with her mother's brain injury and cancer recovery
    This is the most comprehensive ketone science episode we've ever produced.
    TECTON KETONES: Use this link for a discount https://tectonketones.com/discount/TAMATI
    While you're optimising your brain and metabolic health, give your body foundational support with Re:juvenate Pro, my advanced cellular health and longevity formula (https://shop.lisatamati.com/pages/rejuvenate), and explore my full curated range of anti-aging and longevity supplements at shop.lisatamati.com.
    CONNECT WITH LISA Website: lisatamati.com Shop: shop.lisatamati.com
    Newsletter: www.lisatamati.com/lisa
    Podcast: https://www.lisatamati.com/ptl-podcast/
    Books: https://shop.lisatamati.com/collections/books
    Pushing the Limits is brought to you by Lisa Tamati and the team at lisatamati.com.
  • Pushing The Limits

    INUSpheresis: Removing Toxins, Heavy Metals & Microplastics From Blood/ Tash Simons

    20/05/2026 | 52 mins.
    What if the reason you're not getting better isn't about what you're putting in — but what you can't get out?
    In this episode I sit down with Tash Simons from INUSpheresis Perth — the first clinic in Australia and the Southern Hemisphere to offer this advanced blood filtration therapy. We go deep into how double filtration plasmapheresis works, the two specialised filters (TKM58 and INUS 30), and the science behind removing autoantibodies, inflammatory cytokines, heavy metals, microplastics, PCBs, and oxidised LDL directly from your blood — without involving your kidneys or liver.
    We cover the clinical research across long COVID, ME/CFS, autoimmune conditions, Lyme disease, Alzheimer's, and cardiovascular risk including Lp(a) — one of the hardest lipid markers to shift. Tash shares the personal story of how a family member's chronic fatigue led her and Dr Robbie Simons to discover this therapy in Vienna, and the journey to bring it to Perth — from TGA registration and insurance approvals to Swiss certification and over 100 treatments completed.
    If you're dealing with a chronic condition that won't budge, carrying a toxic load, or thinking about longevity from a subtractive medicine perspective — this one's for you.
    Book a consult or submit a new patient form at inuspheresisperth.com.au
    Check out my supplement store at shop.lisatamati.com Rejuvenate Pro at shop.lisatamati.com/pages/rejuvenate My books at shop.lisatamati.com/collections/books Sign up for my newsletter at www.lisatamati.com/lisa Listen to more episodes at www.lisatamati.com/ptl-podcast/
    div]:bg-bg-000/50 [&_pre>div]:border-0.5 [&_pre>div]:border-border-400 [&_.ignore-pre-bg>div]:bg-transparent [&_.standard-markdown_:is(p,blockquote,h1,h2,h3,h4,h5,h6)]:pl-2 [&_.standard-markdown_:is(p,blockquote,ul,ol,h1,h2,h3,h4,h5,h6)]:pr-8 [&_.progressive-markdown_:is(p,blockquote,h1,h2,h3,h4,h5,h6)]:pl-2 [&_.progressive-markdown_:is(p,blockquote,ul,ol,h1,h2,h3,h4,h5,h6)]:pr-8"> _*]:min-w-0 gap-3 standard-markdown"> This episode is also brought to you by Rejuvenate Pro from Aevum Labs. If INUSpheresis is about taking the bad stuff out, Rejuvenate Pro is about protecting what stays behind. Featuring kawakawa, carnosic acid, Immunel colostrum extract and IDP (Immune Defense Protein), it targets the chronic systemic inflammation that silently drives aging. It's the first supplement in every protocol I build for my clients — and it should be in yours. Shop now at shop.lisatamati.com/pages/rejuvenate





     

     
     
     







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     🌐 Website: https://www.lisatamati.com
    🛒 Supplements: https://shop.lisatamati.com
     📧 Contact: support@lisatamati.com
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  • Pushing The Limits

    Copper, Mitochondria Grey Hair & Autism: The Missing Link No One Is Talking About

    15/05/2026 | 52 mins.
    Could a simple mineral deficiency be driving mitochondrial dysfunction in autism? In this episode I sit down with Melissa Atchley from MitoSynergy to hear her personal story of using BioCopper1 with her son on the autism spectrum — and the changes she saw that no one expected.
    I break down the science behind it: Dr Richard Frye's research showing Complex IV dysfunction in children with ASD, the brand new April 2026 Science Advances paper linking copper deficiency directly to ASD-like behaviours through mitochondrial damage and impaired myelination, and why the type of copper matters — Cu1+ vs Cu2+ — more than most people realise.
    We also cover MitoSynergy's new MitoActivator MAX (4x the strength of the standard formula), the hair greying reversal angle, athletic performance benefits, and practical dosing guidance. If you or someone you love is navigating autism, fatigue, grey hair, or just wants to understand why copper might be the most overlooked mineral in health — this one is worth your time.
    Get yours in my shop: https://shop.lisatamati.com/products/mitoactivator-max-max-strength-biocopper1-supplement-60-capsmitosynergy-mitoactivator-max?_pos=2&_sid=5c471c21c&_ss=r
     
    Or use code LisaTamati at Mitosynergy.com for your discount
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About Pushing The Limits
Pushing the limits - the show that gets deep into the psyche of limit pushers from all walks of life. Out the box thinker, elite athlete, successful entrepreneurs, social change innovators, scientists and more. Cutting to the chase to find out what makes them so successful, how they did it, what their life philosophies are and what gems of wisdom they can impart to us all. Hosted by Professional Adventure Athlete Lisa Tamati, author, producer, motivational speaker and mindset coach
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