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Modern Thyroid and Wellness

McCall McPherson, PA-C
Modern Thyroid and Wellness
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92 episodes

  • Modern Thyroid and Wellness

    92: Could Chronic Inflammation Be the Missing Link? The Science Behind Sulforaphane, Detoxification, and Cellular Health with David Roberts & Dr. John Gildea

    30/07/2026 | 53 mins.
    What if the key to better thyroid health, metabolism, and longevity starts at the cellular level?
    In this episode of Modern Thyroid and Wellness, McCall McPherson is joined by David Roberts and Dr. John Gildea, the founders of Mara Labs, to explore the science behind chronic inflammation, oxidative stress, detoxification, and why bioavailability is one of the most overlooked factors in nutritional supplementation.
    David shares the deeply personal story that inspired Mara Labs after his wife Mara's battle with breast cancer, while Dr. Gildea explains how his own scientific research led him to develop innovative ways to improve the absorption of powerful natural compounds like sulforaphane and curcumin. Together, they discuss how environmental toxins, poor nutrition, gut barrier dysfunction, and chronic inflammation may contribute to many of today's chronic health conditions—and why supporting the body's natural detoxification pathways is more important than ever.
    Key Topics Covered
    The personal story behind the founding of Mara Labs
    Why bioavailability matters more than simply taking supplements
    What sulforaphane is and why it has become one of the most researched plant compounds
    The role of chronic inflammation in long-term health
    Oxidative stress and its relationship to chronic disease
    Understanding NRF2 and the body's natural antioxidant defenses
    Phase I, Phase II, and Phase III detoxification
    How gut barrier function influences toxin exposure
    Environmental toxins, microplastics, and endocrine disruption
    Practical ways to reduce your toxic burden
    The connection between inflammation and thyroid hormone function
    How sulforaphane and curcumin may support healthy cellular function
    Why personalized medicine matters
    The science behind GLPerfect™, BrocElite®, CurcuElite®, BerbElite®, and Microplast-X™

    From Personal Tragedy to Purpose
    Mara Labs was born from an incredibly personal journey.
    After David Roberts' wife Mara was diagnosed with breast cancer, he partnered with scientist Dr. John Gildea to better understand natural compounds that could support cellular health. Their research led them to sulforaphane, a compound naturally found in broccoli sprouts, but they quickly discovered that creating a stable, bioavailable form was one of the biggest scientific challenges.
    Following Mara's passing, David and John committed themselves to bringing scientifically formulated, highly bioavailable nutritional supplements to market in her honor.
    Why Bioavailability Matters
    One of the biggest themes throughout the conversation is that the quality of a supplement depends on much more than the ingredient listed on the label.
    Many natural compounds show remarkable results in laboratory studies but are poorly absorbed by the human body.
    David and Dr. Gildea explain how Mara Labs focuses on improving bioavailability so these compounds can actually reach the cells where they are intended to work.
    Rather than simply increasing dosage, their research has centered on improving delivery.
    Chronic Inflammation Starts Long Before Disease
    The conversation explores how chronic disease often develops years before a formal diagnosis.
    Dr. Gildea explains that declining nutrient density, increasing environmental toxin exposure, oxidative stress, and chronic low-grade inflammation gradually affect cellular function over time.
    Whether those changes eventually appear as thyroid disease, metabolic dysfunction, autoimmune conditions, or another chronic illness often depends on an individual's genetics, lifestyle, and overall resilience.
    Detoxification Is More Than a Trend
    Detoxification is often misunderstood.
    The guests explain that true detoxification involves multiple phases that occur throughout the body—not just in the liver—and depends on properly transforming, processing, and eliminating toxins.
    They also emphasize that reducing exposure remains just as important as supporting the body's detoxification pathways.
    Simple strategies discussed include improving indoor air quality with HEPA filtration, drinking filtered water, choosing less processed foods, and purchasing food from trusted local sources whenever possible.
    NRF2: The Master Switch for Cellular Protection
    A major focus of the episode is NRF2, one of the body's primary cellular defense pathways.
    The guests explain how sulforaphane activates NRF2, supporting antioxidant production, Phase II detoxification, cellular resilience, and healthy inflammatory responses.
    Curcumin is also discussed as another compound that complements these pathways while supporting a balanced inflammatory response.
    Together, these compounds may help support overall cellular health through multiple biological mechanisms.
    Environmental Toxins and Microplastics
    David and Dr. Gildea discuss the growing concern surrounding microplastics and endocrine-disrupting chemicals.
    They explain how microplastics may carry additional toxins into the body while potentially interfering with normal hormonal signaling.
    The conversation also introduces Microplast-X™, a newer Mara Labs product designed to support the body's natural ability to remove accumulated microplastics.
    Supporting Metabolic Health
    The discussion also explores GLPerfect™, a supplement developed to support healthy metabolism using highly bioavailable natural compounds.
    Rather than replacing prescription GLP-1 medications, the product was designed as a nutritional approach that supports several pathways involved in appetite regulation, blood sugar balance, fat metabolism, and muscle preservation.
    The conversation highlights the importance of viewing metabolism through a broader lens than weight loss alone.
    Thyroid Health and Cellular Function
    McCall connects many of the concepts discussed back to thyroid health.
    She explains that many patients produce adequate thyroid hormone but struggle with activation, conversion, or cellular utilization.
    Reducing inflammation, supporting antioxidant defenses, and improving overall cellular health may help create a healthier environment for thyroid hormone function.
    The discussion also explores the relationship between inflammation and Hashimoto's thyroiditis and why supporting the body's underlying physiology may benefit overall wellness.
    Final Takeaway
    David Roberts and Dr. John Gildea remind us that long-term health begins long before disease is diagnosed.
    Supporting healthy cellular function, reducing chronic inflammation, minimizing toxic exposures, and improving nutrient bioavailability all contribute to building a stronger foundation for lifelong health.
    Rather than searching for a single miracle solution, lasting wellness often comes from consistently supporting the body's natural systems and choosing interventions backed by thoughtful science.
    About the Guests
    David Roberts is the co-founder and Managing Partner of Mara Labs. Inspired by his wife Mara's battle with breast cancer, he helped establish the company to develop highly bioavailable nutritional supplements focused on supporting cellular health, detoxification, and longevity.
    Dr. John Gildea is the co-founder and Chief Science Officer of Mara Labs. A molecular biologist and researcher, his work focuses on cellular biology, oxidative stress, nutrient bioavailability, inflammation, and the development of innovative nutritional compounds that support healthy aging.
    Resources & Links
    🌐 Mara Labs
    📸 Mara Labs Instagram
    🎙️ Mara Labs Podcast

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  • Modern Thyroid and Wellness

    91: When Standard Treatment Isn’t Enough: How Root-Cause and Regenerative Medicine Changed Nicole Peterson Doran’s Health

    23/07/2026 | 39 mins.
    What if PCOS, thyroid dysfunction, chronic inflammation, fertility concerns, and post-viral illness aren’t completely separate health problems, but connected chapters of a much bigger story?
    In this episode of Modern Thyroid and Wellness, McCall McPherson sits down with Nicole Peterson Doran, co-founder of PUR-FORM and host of The Healthspan Collective podcast. Nicole shares her personal journey from being diagnosed with PCOS at just 16 and later hypothyroidism to discovering functional and integrative medicine, preparing for pregnancy, navigating long COVID and mast cell activation syndrome, and ultimately helping build businesses focused on personalized health optimization and regenerative medicine.
    Together, McCall and Nicole explore why there is no one-size-fits-all approach to healing, how foundational habits and personalized care can work together, and how emerging tools such as GLP-1 medications, peptides, EBO2, and regenerative therapies are becoming part of a broader conversation around complex health challenges.
    🔑 Key Topics Covered
    Nicole’s PCOS diagnosis at age 16
    Developing hypothyroidism after her PCOS diagnosis
    Weight gain, inflammation, fatigue, brain fog, and hormonal symptoms
    Why birth control and metformin did not address everything she was experiencing
    How functional and integrative medicine changed her health journey
    Moving beyond calorie counting toward whole-food nutrition
    Why bio-individuality matters in nutrition and treatment
    The importance of sleep, blood sugar balance, nutrition, and stress management
    Nicole’s fertility fears after being diagnosed with PCOS
    How she prepared her body before trying to conceive
    Her experience becoming pregnant after years of worrying about fertility
    How severe stress and COVID triggered another health crisis
    Long COVID and mast cell activation syndrome (MCAS)
    The relationship between gut health, immune regulation, stress, and inflammation
    Nicole’s personal experience with microdosed GLP-1 therapy
    Thymosin alpha-1 and larazotide discussed during her recovery
    EBO2 and its role in Nicole and McCall’s personal health journeys
    Regenerative medicine and stem cell therapies at PUR-FORM
    PUR-FORM’s newly launched MUSE cell offering
    Therapeutic plasma exchange and health optimization
    Why finding one practitioner who truly listens can change your health journey

    Nicole’s Health Journey Started at 16
    Nicole had been a healthy athlete when her health suddenly changed during her teenage years.
    Within months, she gained approximately 30 pounds, developed facial hair and irregular periods, struggled with severe fatigue, and experienced significant brain fog.
    After seeing multiple specialists, her mother took her to a trusted OB/GYN who decided to investigate her hormones and thyroid more deeply. Nicole was diagnosed with PCOS and, a year or two later, hypothyroidism.
    She was prescribed birth control and metformin. While these treatments addressed certain aspects of her condition, Nicole still struggled with her weight, inflammation, and energy.
    She knew she needed to look deeper.
    Discovering a Different Approach to Health
    A major turning point came after college when Nicole began working with a health coach.
    Instead of obsessively tracking calories and macros, she shifted her attention toward whole foods and began exploring how nutrition, stress, mindfulness, and emotional wellbeing influenced her health.
    She noticed her inflammation gradually improving.
    The experience ultimately inspired Nicole to study at the Institute for Integrative Nutrition, where she was introduced to a concept that became central to her approach to health: bio-individuality.
    What works for one person may not work for another.
    Nicole personally thrives living gluten-free, but she emphasizes that this does not mean everyone needs to eliminate gluten. Intermittent fasting may transform one person’s health while being completely wrong for someone else.
    McCall sees the same principle in thyroid care. There is no universally “best” thyroid medication or diet because each person’s physiology and needs are different.
    However, certain foundations remain important for almost everyone: whole-food nutrition, balanced blood sugar, quality sleep, movement, and stress management.
    PCOS, Fertility, and Preparing for Pregnancy
    When Nicole was diagnosed with PCOS as a teenager, she was told becoming pregnant might be difficult.
    The message stayed with her because she had always wanted to become a mother.
    Years later, when pregnancy became a priority, Nicole intentionally focused on creating the healthiest foundation she could.
    Working with her practitioners, she focused on lowering inflammation and supporting her overall health through personalized nutrition and supplementation. She discusses CoQ10 and fish oil, reducing sugar, eliminating alcohol, continuing her gluten-free lifestyle, temporarily removing dairy, and significantly reducing travel and stress.
    Perhaps most importantly, she gave herself permission to slow down.
    Nicole became pregnant after approximately three months of trying.
    She acknowledges that fertility is complex and that no lifestyle strategy can guarantee pregnancy. Still, her experience offers an encouraging perspective for women who fear that a PCOS diagnosis automatically means they will be unable to conceive.
    When Long COVID Triggered a New Health Crisis
    By 2023, Nicole felt healthier than she had in years.
    Then she contracted COVID during an intensely stressful period surrounding the launch of her business and her wedding.
    She became severely ill just days before getting married. After the acute infection passed, unusual symptoms remained.
    Nicole began experiencing significant histamine reactions, inflammation, weight changes, brain fog, fatigue, and irritability.
    Eventually, a practitioner recognized symptoms consistent with mast cell activation syndrome in the context of her post-viral health challenges.
    This became another turning point in how Nicole understood her body.
    Her immune system, gut health, inflammation, stress, and metabolic health were not operating independently. They were deeply interconnected.
    GLP-1s, Peptides, and Personalized Medicine
    Nicole worked with practitioners to explore different strategies during her recovery.
    She shares her personal experience with microdosed tirzepatide, a GLP-1-based medication, which she describes as an important tool for her own inflammation and metabolic health.
    She also discusses peptides, including thymosin alpha-1 in the context of immune support and larazotide in relation to gut barrier health.
    Gut health has been a recurring theme throughout Nicole’s health journey. She describes how periods of intense stress seemed to coincide with worsening inflammation and digestive health, reinforcing her belief that the body must be viewed as an interconnected system.
    The larger message is not that everyone needs the same medication, peptide, diet, or intervention.
    Personalized medicine means selecting tools according to the individual.
    What Is EBO2?
    McCall and Nicole also discuss EBO2, short for extracorporeal blood oxygenation and ozonation.
    Nicole explains that PUR-FORM offers EBO2 and trains other clinics in the protocol. The procedure involves circulating blood outside the body through a system involving filtration, oxygen, and ozone before returning it to the patient.
    Nicole shares that EBO2 has been part of her own health strategy outside of pregnancy.
    The topic is also deeply personal for McCall, who shares that she underwent EBO2 while struggling significantly with long COVID and credits the treatment as an important turning point in her own recovery.
    Their experiences lead to a broader conversation about the evolving field of regenerative medicine and the need to evaluate advanced therapies based on each patient’s individual circumstances.
    From Patient to Entrepreneur
    Nicole’s difficult health experiences eventually became part of her professional mission.
    She remembers working incredibly hard on her health while feeling as though her body simply would not respond.
    Years of inflammation, fatigue, weight struggles, and frustration also contributed to an unhealthy relationship with food at different points in her journey.
    Today, Nicole is running multiple businesses while preparing to become a mother.
    Her transformation inspired a commitment: if she could better understand her own health, she wanted to help other people avoid some of the confusion and frustration she experienced.
    That mission became part of the work behind PUR-FORM.
    Regenerative Medicine at PUR-FORM
    PUR-FORM is a comprehensive health optimization clinic based in Boca Raton, Florida.
    Nicole discusses working with orthopedic surgeon Dr. Joseph Purita and her family to expand access to integrative and regenerative therapies.
    Services discussed during the episode include:
    Stem cell and regenerative therapies
    EBO2
    Therapeutic plasma exchange
    IV therapies
    Red light therapy
    Infrared sauna
    Cold plunge
    Cryotherapy

    Nicole also shares an important new development: PUR-FORM recently launched a MUSE cell offering as part of its regenerative medicine services.
    She
  • Modern Thyroid and Wellness

    90: Too Much Iron Can Be Just as Dangerous as Too Little – The Hidden Condition Behind Fatigue, Heart Disease, and Thyroid Problems with Dr. Christy Sutton

    16/07/2026 | 34 mins.
    What if one of the most overlooked causes of fatigue, joint pain, thyroid dysfunction, and even heart disease wasn't iron deficiency, but iron overload?
    In this episode of Modern Thyroid and Wellness, McCall McPherson welcomes Christy Sutton, chiropractor, functional medicine clinician, educator, and author of The Iron Curse. Inspired by her husband's diagnosis with hereditary hemochromatosis, Dr. Sutton has dedicated her work to helping patients recognize and address iron overload before it leads to serious long-term health complications.
    Together, McCall and Dr. Sutton explore why hereditary hemochromatosis is far more common than many people realize, why millions of people may unknowingly carry high-risk genes, and how excess iron can silently damage the liver, heart, pancreas, brain, thyroid, and other organs. McCall also shares her own personal experience with iron overload, walking through her lab work live during the episode while Dr. Sutton explains what the results reveal and why early detection can make all the difference.
    Whether you're experiencing unexplained fatigue, elevated ferritin, thyroid issues, or have a family history of iron overload, this episode offers practical guidance on testing, treatment, and understanding one of the most underdiagnosed conditions in modern medicine.

    🔑 Key Topics Covered
    What hereditary hemochromatosis is and why it's commonly missed
    Why iron overload can be just as dangerous as iron deficiency
    The three HFE gene variants associated with hereditary hemochromatosis
    Why being told you're "just a carrier" may not tell the full story
    How excess iron creates oxidative stress throughout the body
    The connection between iron overload and liver disease
    How excess iron may contribute to cardiovascular disease and plaque formation
    Iron overload and its relationship with thyroid dysfunction
    Why iron can accumulate in the brain, pancreas, pituitary gland, and joints
    The impact of iron overload on hormone production and fertility
    Why women often develop iron overload after menopause or uterine ablation
    McCall's personal lab review and genetic results
    Understanding ferritin, transferrin saturation, and inflammatory markers
    Why ferritin should always be interpreted alongside CRP
    The role of therapeutic blood removal in treatment
    Blood donation versus therapeutic phlebotomy
    Dietary strategies to help manage iron overload
    Why vitamin C supplementation may increase iron absorption
    Foods and beverages that influence iron absorption
    Supplements that may support healthy iron regulation
    The relationship between celiac disease genes and iron metabolism
    Why family history plays an important role in early detection


    🩸 Iron Overload Is More Common Than Most People Think
    When most people think about iron, they think about deficiency.
    But according to Dr. Sutton, hereditary hemochromatosis affects far more people than many realize, with a significant portion of the population carrying one or more HFE gene variants that can increase iron absorption.
    Because the body has very limited ways to eliminate excess iron, levels can gradually increase over decades, especially after menstruation ends or blood loss decreases.

    🧬 Why Excess Iron Can Damage the Entire Body
    Iron is essential for life, but too much can become harmful.
    Dr. Sutton explains that excess iron contributes to oxidative stress, allowing iron to accumulate within tissues where it may damage organs over time.
    Areas commonly affected include:
    Liver
    Heart
    Pancreas
    Brain
    Thyroid
    Pituitary gland
    Joints

    Because this process develops slowly, many people don't recognize the problem until significant health issues appear.

    👩 Why Women Often Don't Develop Symptoms Until Midlife
    Premenopausal women naturally lose iron through monthly menstrual cycles.
    As a result, many women remain protected from iron accumulation for years.
    However, after menopause, hysterectomy, uterine ablation, or other situations that reduce menstrual blood loss, iron levels may begin rising much more rapidly.
    McCall shares her own experience of seeing her iron markers increase after uterine ablation, creating an opportunity to discuss how these laboratory changes may appear before significant symptoms develop.

    🩺 Looking Beyond a Single Lab Value
    One of the most educational moments of the episode comes when Dr. Sutton reviews McCall's laboratory results in real time.
    She explains why evaluating multiple markers together provides a more complete picture, including:
    Ferritin
    Transferrin saturation
    Complete blood count
    Red blood cell markers
    C-reactive protein (CRP)

    Because ferritin can rise with both inflammation and excess iron, understanding the broader laboratory context becomes essential when determining the underlying cause.

    ❤️ Iron Overload and Heart Health
    The discussion also explores the relationship between excess iron and cardiovascular health.
    According to Dr. Sutton, elevated iron may contribute to oxidative stress that damages blood vessels and promotes inflammation.
    Over time, this process may play a role in plaque formation and increase cardiovascular risk in susceptible individuals.
    McCall also shares the personal story of losing her brother unexpectedly to a heart attack, highlighting why this topic carries such deep personal significance for her family.

    💉 Treatment Starts by Reducing Iron
    The primary treatment for hereditary hemochromatosis involves removing excess iron through therapeutic phlebotomy or blood donation when medically appropriate.
    By removing blood, the body uses stored iron to produce new red blood cells, gradually lowering overall iron stores.
    Dr. Sutton explains that treatment plans should always be individualized and that blood removal is not appropriate for everyone.

    🥩 Everyday Habits That Influence Iron Levels
    In addition to therapeutic blood removal, lifestyle choices can influence iron absorption.
    Dr. Sutton discusses strategies such as:
    Moderating red meat intake when iron levels are elevated
    Pairing iron-rich meals with tea or coffee, which may reduce iron absorption
    Avoiding unnecessary vitamin C supplements with iron-rich meals
    Supporting overall health through individualized nutrition and supplementation

    She also discusses compounds such as curcumin, green tea extract, quercetin, and alpha-lipoic acid that are being studied for their role in supporting healthy iron regulation.

    🌟 Final Takeaway
    Iron deficiency deserves attention, but so does iron overload.
    Because hereditary hemochromatosis often develops silently over many years, understanding your genetics, reviewing your laboratory markers, and paying attention to family history may help identify problems before long-term complications develop.
    As Dr. Sutton explains throughout this conversation, awareness is one of the most powerful tools we have.
    Early testing, thoughtful interpretation of laboratory results, and individualized treatment can help protect long-term health while preventing unnecessary organ damage.

    👤 About the Guest
    Christy Sutton is a chiropractor, functional medicine clinician, educator, and author specializing in genetics, iron metabolism, and chronic disease prevention. Inspired by her husband's diagnosis with hereditary hemochromatosis, she developed educational resources to help patients and practitioners better understand iron overload, genetic risk factors, and root-cause approaches to long-term health.

    🔗 Resources & Links
    📖 The Iron Curse by Dr. Christy Sutton
    The Iron Curse Book
    🎓 The Iron Curse Educational Workshop
    The Iron Curse Workshop
    🌐 Website:
    Dr. Christy Sutton
    📸 Instagram:
    Dr. Christy Sutton Instagram
    🎵 TikTok:
    Dr. Christy Sutton TikTok
    💼 LinkedIn:
    Dr. Christy Sutton LinkedIn
    📲 Follow McCall McPherson & Modern Thyroid and Wellness
    💻 Website: modernthyroidclinic.com
    🐦 X / Twitter: @thyroidexpert
    🌐 Host Website: mccallmcpherson.com
    📺 YouTube:
  • Modern Thyroid and Wellness

    89: Autoimmune Disease Is Rising Faster Than Ever – The Root Causes Conventional Medicine Still Misses with Dr. Amy Myers

    09/07/2026 | 53 mins.
    What if autoimmune disease isn't something you're destined to live with forever, but a signal that your body needs help addressing deeper root causes?
    In this episode of Modern Thyroid and Wellness, McCall McPherson welcomes longtime mentor, friend, and functional medicine pioneer Amy Myers. A two-time New York Times bestselling author and internationally recognized functional medicine physician, Dr. Myers shares her personal journey from being diagnosed with Graves' disease during medical school to becoming one of the leading voices in autoimmune and thyroid health.
    Together, they explore why autoimmune diseases continue to rise, why women are disproportionately affected, and why many patients spend years searching for answers before receiving a diagnosis. Dr. Myers explains the role of gut health, environmental toxins, infections, stress, trauma, and nutrition in autoimmune disease while sharing practical strategies for supporting immune health and addressing root causes. She also introduces the newly revised edition of The Autoimmune Solution, featuring updated research and expanded guidance for today's changing health landscape.
    Whether you're living with Hashimoto's, Graves' disease, or another autoimmune condition, this conversation offers hope, practical tools, and a reminder that healing begins by understanding the "why" behind your symptoms.
    🔑 Key Topics Covered
    Dr. Amy Myers' personal journey with Graves' disease
    Why autoimmune diseases continue to rise worldwide
    The connection between environmental toxins and autoimmune disease
    Why women are disproportionately affected by autoimmune conditions
    Common reasons autoimmune diseases are missed for years
    The impact of medical gaslighting on thyroid and autoimmune patients
    How long autoimmune disease can develop before diagnosis
    Why antibodies should be checked even before symptoms become severe
    The autoimmune spectrum and recognizing early warning signs
    Genetics versus environment: what really drives autoimmune disease
    The four pillars of autoimmune healing
    Why gut health is foundational for immune regulation
    The role of leaky gut in autoimmune disease
    Candida, SIBO, parasites, and hidden gut infections
    Food triggers including gluten and processed foods
    Environmental toxins, plastics, mold, and chemical exposure
    Supporting the body's natural detoxification pathways
    The relationship between chronic infections, stress, trauma, and autoimmunity
    Why Hashimoto's remission looks different than stopping thyroid hormone
    Monitoring thyroid antibodies over time
    Hope for reversing autoimmune disease through root-cause medicine

    🌿 From Graves' Disease to Functional Medicine
    Dr. Myers' journey into functional medicine began with her own health crisis.
    While attending medical school, she developed severe anxiety, tremors, insomnia, weight loss, and other symptoms that were initially dismissed as stress.
    After insisting on additional testing, she was diagnosed with Graves' disease.
    Although conventional treatment successfully managed her thyroid, she realized no one had addressed why her immune system attacked her thyroid in the first place.
    That experience ultimately led her to discover functional medicine and dedicate her career to helping patients identify and address the root causes of autoimmune disease.
    🧬 Why Autoimmune Disease Is Becoming More Common
    According to Dr. Myers, autoimmune disease isn't simply being diagnosed more often.
    She believes multiple environmental factors are contributing to a true increase in autoimmune conditions.
    Among the biggest contributors discussed are:
    Environmental toxins
    Chronic infections
    Processed foods
    Plastic exposure
    Chronic stress
    Gut dysfunction
    Modern lifestyle changes

    She explains that while genetics influence susceptibility, environmental exposures often determine whether those genes become active.
    👩 Why Women Are More Commonly Affected
    Women account for the majority of autoimmune diagnoses.
    Dr. Myers explains that significant hormonal transitions often coincide with the development or worsening of autoimmune disease.
    Common life stages include:
    Pregnancy
    Postpartum
    Perimenopause
    Menopause

    These hormonal shifts can influence immune regulation and may contribute to the onset of autoimmune symptoms in genetically susceptible individuals.
    ⏳ Autoimmunity Often Begins Years Before Diagnosis
    One of the most important messages in this episode is that autoimmune disease develops long before many people receive a diagnosis.
    Dr. Myers explains that antibodies may be present for years before symptoms become severe enough to trigger additional testing.
    During this time, people often experience symptoms such as:
    Fatigue
    Brain fog
    Hair loss
    Joint pain
    Digestive problems
    Weight changes

    Unfortunately, these symptoms are frequently attributed to stress, aging, or hormonal changes rather than early autoimmune disease.
    🩺 The Four Pillars of Autoimmune Healing
    Dr. Myers describes a comprehensive approach that focuses on identifying and addressing the underlying drivers of immune dysfunction.
    Her four pillars include:
    Heal the Gut
    Supporting digestion and restoring the intestinal barrier through nutrition, digestive support, probiotics, and treatment of underlying gut infections.
    Improve Nutrition
    Removing inflammatory foods while emphasizing nutrient-dense whole foods that support immune balance.
    Reduce Toxic Burden
    Minimizing exposure to environmental toxins while supporting the body's natural detoxification pathways through hydration, sweating, regular bowel movements, and targeted nutritional support.
    Address Hidden Triggers
    Identifying chronic infections, reducing stress, and addressing unresolved trauma that may contribute to persistent immune activation.
    Together, these pillars form the foundation of her functional medicine approach to autoimmune health.
    🦠 Why Gut Health Comes First
    Dr. Myers refers to the gut as "the gateway to health."
    She explains that many people with autoimmune disease also experience:
    Leaky gut
    Candida overgrowth
    SIBO
    Parasites
    Poor digestion

    Before attempting to rebuild the microbiome, she emphasizes identifying and treating these underlying issues while also removing inflammatory foods that may continue to drive immune dysfunction.
    🧪 Monitoring Thyroid Antibodies
    For thyroid patients, Dr. Myers emphasizes that antibody testing provides valuable information beyond standard thyroid hormone levels.
    She recommends:
    Establishing baseline antibody levels
    Monitoring antibodies more frequently during active treatment
    Periodic long-term monitoring once antibodies remain stable

    She also notes that patients who have undergone thyroid ablation or thyroid surgery may still produce thyroid antibodies and should continue monitoring when appropriate.

    🌟 Final Takeaway
    Autoimmune disease is not simply a matter of bad luck or genetics.
    As Dr. Myers explains, our environment, nutrition, gut health, stress, infections, and daily habits all influence how our immune system functions.
    While every autoimmune journey is unique, understanding and addressing these root causes can create meaningful opportunities for healing and improved quality of life.
    Most importantly, a diagnosis doesn't have to mean giving up hope.
    With the right approach, many people can reduce inflammation, improve symptoms, and support long-term immune health.
    👤 About the Guest
    Amy Myers is a physician, certified functional medicine practitioner, founder of Amy Myers MD®, and a two-time New York Times bestselling author. After overcoming her own battle with Graves' disease, she became a leading voice in autoimmune and thyroid health, helping thousands of people address root causes through functional medicine. She is the author of The Autoimmune Solution, The Thyroid Connection, and The Autoimmune Solution Cookbook.
    🔗 Resources & Links
    🌐 Official Website:
    Amy Myers MD
    🌐 Personal Website:
    Dr. Amy Myers
    📺 YouTube:
    Amy Myers MD YouTube
    📚 Books:
    Dr. Amy Myers Amazon Author Page
    🎙️ Podcast: Take Back Your Health
    🎁 Free Gift for MTW Listeners:
    Amy Myers MD / McCall Resource Page
    📲 Follow McCall McPherson &...
  • Modern Thyroid and Wellness

    88: Your Home Could Be Affecting Your Health More Than You Realize – The Hidden Impact of Air, Water, and Everyday Toxins with Helen Christoni

    02/07/2026 | 34 mins.
    What if one of the most powerful ways to support your thyroid, hormones, gut, and long-term health isn't another supplement or medication, but improving the air you breathe and the water you use every day?
    In this episode of Modern Thyroid and Wellness, McCall McPherson welcomes Helen Christoni, Senior Vice President of Ideal Living, the parent company behind AirDoctor and AquaTru. Helen shares her personal health journey, including experiencing early menopause and severe osteoporosis in her early forties, and how that experience led her to become passionate about reducing environmental toxins in the home.
    Together, McCall and Helen explore why clean air and clean water are foundational to health, how everyday environmental exposures contribute to toxic burden, and practical, affordable steps families can take to create a healthier home without feeling overwhelmed.
    🔑 Key Topics Covered
    Helen's personal story of early menopause and severe osteoporosis
    How toxic burden can affect long-term health
    Why clean air and clean water are foundational to wellness
    How to check the quality of your local tap water
    Common contaminants found in municipal water
    Why boiling water can increase contaminant concentration
    Reverse osmosis vs. standard water filters
    Understanding chlorine and chloramine exposure
    Why shower water affects skin, lungs, and overall health
    The growing concern around microplastics and thyroid health
    Simple ways to reduce plastic exposure at home
    Why indoor air is often more polluted than outdoor air
    Wildfires, VOCs, mold, and hidden indoor air contaminants
    Why HEPA filtration alone isn't enough
    The importance of activated carbon in air purification
    How cooking, candles, and personal care products affect indoor air quality
    Creating a healthier bedroom for better sleep and recovery
    Practical healthy-home swaps anyone can start today

    🌿 Helen's Journey to Environmental Wellness
    Helen's passion for clean air and clean water grew out of her own health crisis.
    While working in the beauty industry, she developed severe osteoporosis and entered menopause unexpectedly in her early forties. After multiple fractures and searching for answers, she was encouraged to look beyond conventional health advice and consider the role environmental toxins might be playing in her overall health.
    That experience ultimately brought her back to Ideal Living, where she now focuses on educating families about simple, practical ways to reduce their everyday toxic burden.
    💧 Your Water May Contain More Than You Think
    Many people focus on eating organic foods but rarely consider the quality of the water they drink or cook with.
    Helen explains that municipal water supplies can contain numerous contaminants, including naturally occurring heavy metals and chemical byproducts.
    One of the biggest misconceptions is that boiling water makes it safer.
    Instead, many contaminants become more concentrated as water evaporates during cooking, meaning foods like pasta, rice, soups, and vegetables may contain even higher concentrations than the original tap water.
    She also explains why reverse osmosis filtration removes a broader range of contaminants than standard carbon filters, making it one of the most comprehensive options for drinking and cooking water.
    🚿 Your Shower Is Another Source of Exposure
    Water quality doesn't only matter when you drink it.
    Every shower exposes your body to chlorine, chloramine, and other contaminants through both skin absorption and inhalation.
    Because skin is the body's largest organ, these daily exposures may contribute to:
    Dry skin
    Eczema
    Psoriasis
    Skin irritation
    Increased overall toxic burden

    Helen recommends shower filtration as another simple improvement that supports healthier skin while reducing everyday chemical exposure.
    🌬️ Indoor Air Quality Deserves More Attention
    Most people think about outdoor pollution.
    But according to Helen, indoor air can often be even more polluted because contaminants become trapped inside modern, energy-efficient homes.
    Indoor air may contain:
    Wildfire smoke
    Volatile organic compounds (VOCs)
    Mold spores
    Pet dander
    Household cleaning chemicals
    Cooking emissions
    Personal care product chemicals

    Since most people spend the majority of their day indoors, improving indoor air quality can significantly reduce overall environmental exposure.
    Helen also explains why effective air purification requires both HEPA filtration and activated carbon, since many harmful gases and VOCs cannot be captured by HEPA filters alone.
    🏡 Small Changes Add Up
    One of the biggest messages throughout this conversation is that creating a healthier home doesn't require perfection.
    Helen encourages listeners to focus on simple, repeatable habits like:
    Filtering drinking and cooking water
    Improving bedroom air quality
    Ventilating while cooking
    Choosing cleaner household products
    Reducing plastic use whenever possible
    Selecting organic bedding and textiles when practical

    Rather than trying to change everything overnight, she recommends building healthier habits one step at a time.
    🌟 Final Takeaway
    The environment inside your home influences your health every single day.
    The water you drink.
    The air you breathe.
    The products you use.
    The choices you repeat.
    As Helen explains, reducing toxic burden isn't about creating fear or chasing perfection. It's about making practical improvements that support your body's natural ability to thrive.
    Sometimes the most powerful health interventions aren't found in a prescription bottle.
    They're found in the everyday choices that quietly shape your health for years to come.
    👤 About the Guest
    Helen Christoni is the Senior Vice President of Ideal Living, the parent company of AirDoctor and AquaTru. She is passionate about educating families on environmental wellness, helping people reduce everyday toxic exposures through cleaner air, purified water, and practical healthy-home solutions. Helen is also the co-host of the Make Time Podcast, where she shares conversations focused on wellness, longevity, and intentional living.
    🔗 Resources & Links
    🌐 LinkedIn: Helen Christoni LinkedIn
    📸 Instagram: Helen Christoni Instagram
    🎙️ Podcast: Make Time Podcast with Emma and Helen
    💧 Check Your Local Water Quality:
    Is My Water Safe?
    🌬️ Learn About Air Quality & Why AQI Matters:
    Why Knowing Your AQI Is Essential in Today's Wildfire Era
    📲 Follow McCall McPherson & Modern Thyroid and Wellness
    💻 Website: modernthyroidclinic.com
    🐦 X / Twitter: @thyroidexpert
    🌐 Host Website: mccallmcpherson.com
    📺 YouTube: McCall McPherson Channel
    📘 Facebook: McCall McPherson PAC
    📸 Instagram: @mccallmcphersonpa
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About Modern Thyroid and Wellness
Unlock the latest insights into thyroid health and wellness with McCall McPherson, PA-C. Through expert interviews, personal stories, and actionable advice, this podcast dives deep into thyroid disorders, exploring how they impact everything from energy levels to mental clarity. Whether you're navigating your own thyroid journey or seeking cutting-edge solutions for optimal health, you'll find practical tips and holistic strategies to support your well-being. Join McCall as she empowers listeners to take control of their thyroid health and live a more vibrant life.
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