ResearchPod science podcasts connect the research community to a global audience of peers and the public, raising visibility and impact. www.researchpod.org. Al...
Can PBMCs be used as a tool for the identification of immune biomarkers in lung cancer?
Lung cancer is a leading cause of cancer-related deaths worldwide, with treatment responses varying widely among patients.Dr. Carminia Maria Della Corte from the University of Texas MD Anderson Cancer Center is at the forefront of research into using peripheral blood mononuclear cells (PBMCs) to identify immune biomarkers. Her work explores the cGAS/STING pathway, DDR gene mutations, and advanced 3D tumour models, offering insight into predicting immunotherapy responses and tailoring treatments for non-small and small cell lung cancer.Read the original research: doi.org/10.3390/biomedicines12040809
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PrivacyPrimer: Protecting privacy while supporting memory recall for older adults
Memory is a problem for many people as they age. To combat this, wearable devices may help older adults recall precious memories through what is called 'life-logging', despite these technologies raising significant privacy concerns.Researchers at Singapore Management University, led by Thivya Kandappu, have developed PrivacyPrimer, a tool designed to protect sensitive information captured by wearable cameras. Their approach uses selective image obfuscation to safeguard privacy, while preserving the ability to reminisce - striking a balance between memory recall and security.Read the original research: doi.org/10.1145/3476047
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Resilience, scepticism, and mRNA with Katalin Karikó
While we may associate Messenger RNA (mRNA for short) with the COVID-19 pandemic vaccination programme, its study in fact began over 60 years ago.Born in 1955 in rural Hungary, Katalin Karikó battled critics and scepticism for her research into mRNA for over 30 years before its role in the COVID-19 vaccination programme gained her recognition and, in 2023, a Nobel Prize in Physiology or Medicine. In this interview, Karikó tells us about this journey and why she loves biochemistry, what it’s like to win a Nobel Prize, and how she would advise young scientists today. Read Katalin's book: Breaking Through: My Life in Science Read more in Research OutreachImage credit for Thumbnail : OrionNimrod on Wikimedia commons
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Personalised genetic insights: A revolution in papillary thyroid cancer
While the management of papillary thyroid cancer (PTC) is guided by recurrence risk assessment, current methods cannot accurately predict disease recurrence.Professor Oliver Bathe and his collaborators at the University of Calgary, Canada, have developed a test that includes genetic data linked to recurrence. Together, they identified three molecular PTC subtypes, allowing more accurate risk assessment to guide clinical decision-making and treatment.Read more in Research FeaturesRead the original research: doi.org/10.3389/fendo.2023.1220617
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Early Action Review: Preventing local outbreaks from becoming pandemics
The COVID-19 pandemic was a wake-up call for governments and their global stakeholders to reform the management processes of infectious disease outbreaks. Dr Stella Chungong and Dr Landry Ndriko Mayigane of the Health Security Preparedness Department of the World Health Organization’s Health Emergencies Programme are encouraging countries to implement early action reviews (EARs) for disease outbreaks to assess their vigilance and planning, the responsiveness of their health systems, and to better prepare for outbreaks.Read more in Research OutreachRead the original research: doi.org/10.1016/S2214-109X(23)00167-5
ResearchPod science podcasts connect the research community to a global audience of peers and the public, raising visibility and impact. www.researchpod.org. All content is shared under the Creative Commons CCBY-NC-ND 4.0 licence. For further information, email [email protected]
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