PodcastsAlternative HealthThe Longevity & Lifestyle Podcast

The Longevity & Lifestyle Podcast

Claudia von Boeselager
The Longevity & Lifestyle Podcast
Latest episode

259 episodes

  • The Longevity & Lifestyle Podcast

    #257 Dr. Dale Bredesen — Can Alzheimer's Be Prevented? New Trial Results & Brain Biomarkers

    09/07/2026 | 55 mins.
    Ready to unlock your brain’s superpower? Download my free 5-Minute Brain Blueprint to boost mental clarity, sharpen focus, and support lifelong cognitive vitality → https://longevity-and-lifestyle.com/BRAIN

    What if cognitive decline is not as inevitable as we have been told?
    In this episode of the Longevity & Lifestyle Podcast, I welcome back Dr. Dale Bredesen, internationally recognized neurologist, bestselling author, and pioneer in the prevention and reversal of cognitive decline.

    Dr. Bredesen shares the findings from his latest randomized controlled trial, in which 90% of participants receiving a precision medicine protocol improved. We explore why Alzheimer’s may begin decades before symptoms appear, the biomarkers that can help identify risk earlier, and the lifestyle and medical factors that may influence cognitive health.

    We also discuss the role of sleep, insulin resistance, inflammation, toxins, ketones, peptides, stem cells, GLP-1 medications, psychedelics, and neuroplasticity.

    This conversation offers an important message: the earlier we understand what is driving cognitive decline, the greater the opportunity to act.

    In this episode, you’ll learn:
    • Why Alzheimer’s may begin decades before symptoms
    • What Dr. Bredesen’s latest trial revealed
    • The stages from prevention to dementia
    • Blood biomarkers linked to early decline
    • Insulin resistance, ketones, and brain energy
    • Sleep apnea and long-term brain health
    • Why there is no single cure

    TIMESTAMPS
    00:00 Introduction
    03:37 The Alzheimer’s trial where 90% improved
    06:35 What drives cognitive decline
    12:01 Why Alzheimer’s is no longer viewed as hopeless
    16:08 The four stages of cognitive decline
    18:22 Blood tests that may reveal risk earlier
    22:22 The key drivers of Alzheimer’s
    23:36 The seven foundations of brain health
    25:53 Sleep targets for cognitive longevity
    28:27 GLP-1s and Alzheimer’s risk
    31:35 Peptides for brain health
    35:59 Stem cells, exosomes, and regenerative medicine
    39:32 Is there hope at every stage?
    40:45 Inside the randomized clinical trial
    46:18 Psychedelics and neuroplasticity
    52:31 Dr. Bredesen’s final message

    CONNECT WITH DR. DALE BREDESEN
    Website: https://www.drbredesen.com
    Free cognitive assessment: https://www.mycqtest.com
    Brain biomarker testing: https://www.getabrainscan.com

    CONNECT WITH CLAUDIA
    Website: https://longevity-and-lifestyle.com
    Instagram: https://www.instagram.com/longevityandlifestyle
    LinkedIn: https://www.linkedin.com/in/claudiavonboeselager
    YouTube: https://www.youtube.com/@LongevityandLifestyle

    Subscribe to the Longevity & Lifestyle Podcast for more conversations with leading scientists, physicians, founders, and innovators shaping the future of health and human performance.

    #DaleBredesen #Alzheimers #BrainHealth #CognitiveDecline #DementiaPrevention #Longevity #PrecisionMedicine #Neuroplasticity #HealthyAging #LongevityPodcast
  • The Longevity & Lifestyle Podcast

    #256 Dr. Ian White — Repairing the Aging Body: Amniotic Fluid, Muse Cells & Regenerative Medicine

    01/07/2026 | 59 mins.
    What if the real key to longevity is not just preventing damage - but restoring the body’s ability to repair itself?

    In this episode, I sit down with Dr. Ian White, a leading expert in regenerative medicine, stem cell biology, tissue regeneration, and longevity science. We explore how amniotic fluid, Muse cells, and regenerative signaling may help support healing, reduce inflammation, and change the future of longevity medicine.

    We also break down what regenerative medicine actually is, how it differs from the way most people talk about stem cells, what matters most for safety, and how this field could reshape the way we think about aging and recovery.

    In this conversation, we cover:
    00:00 - The accidental discovery that changed regenerative science
    00:40 - Could the answer to longevity begin before birth?
    02:23 - Dr. Ian White’s path into regenerative medicine
    05:13 - Why some animals regrow tissue and humans do not
    07:26 - What changes in the body’s repair systems with age
    09:29 - Why amniotic fluid is so scientifically interesting
    12:55 - What regenerative medicine really means
    15:05 - Longevity, healing, and the biology of repair
    16:30 - Stem cells vs regenerative medicine
    21:05 - Regulation, safety, and responsible clinical use
    24:13 - Tissue repair and real-world applications
    28:37 - Brain health and regenerative medicine
    31:39 - Rejuvenation and the future of anti-aging medicine
    39:05 - Muse cells and why they matter
    43:40 - Who may benefit most from these therapies
    46:37 - How to approach regenerative medicine responsibly
    50:23 - Space aging research and the future of longevity science
    54:25 - Final thoughts on healing, aging, and what comes next

    If you enjoyed this episode, subscribe and share it with someone serious about living longer, healthier, and better.

    #Longevity #RegenerativeMedicine #StemCells #HealthyAging #Biohacking #TissueRepair #AntiAging #HealthOptimization
  • The Longevity & Lifestyle Podcast

    #256 Dr. Ian White — Repairing the Aging Body: Amniotic Fluid, Muse Cells & Regenerative Medicine

    01/07/2026 | 58 mins.
    What if the real key to longevity is not just preventing damage - but restoring the body’s ability to repair itself?

    In this episode, I sit down with Dr. Ian White, a leading expert in regenerative medicine, stem cell biology, tissue regeneration, and longevity science. We explore how amniotic fluid, Muse cells, and regenerative signaling may help support healing, reduce inflammation, and change the future of longevity medicine.

    We also break down what regenerative medicine actually is, how it differs from the way most people talk about stem cells, what matters most for safety, and how this field could reshape the way we think about aging and recovery.

    In this conversation, we cover:
    00:00 - The accidental discovery that changed regenerative science
    00:40 - Could the answer to longevity begin before birth?
    02:23 - Dr. Ian White’s path into regenerative medicine
    05:13 - Why some animals regrow tissue and humans do not
    07:26 - What changes in the body’s repair systems with age
    09:29 - Why amniotic fluid is so scientifically interesting
    12:55 - What regenerative medicine really means
    15:05 - Longevity, healing, and the biology of repair
    16:30 - Stem cells vs regenerative medicine
    21:05 - Regulation, safety, and responsible clinical use
    24:13 - Tissue repair and real-world applications
    28:37 - Brain health and regenerative medicine
    31:39 - Rejuvenation and the future of anti-aging medicine
    39:05 - Muse cells and why they matter
    43:40 - Who may benefit most from these therapies
    46:37 - How to approach regenerative medicine responsibly
    50:23 - Space aging research and the future of longevity science
    54:25 - Final thoughts on healing, aging, and what comes next

    If you enjoyed this episode, subscribe and share it with someone serious about living longer, healthier, and better.

    #Longevity #RegenerativeMedicine #StemCells #HealthyAging #Biohacking #TissueRepair #AntiAging #HealthOptimization
  • The Longevity & Lifestyle Podcast

    #255 Dr. Alexander Grinberg — Peptides Without Hype: What Actually Works & The Future of Longevity

    26/06/2026 | 57 mins.
    In this episode of the Longevity & Lifestyle Podcast, Claudia von Boeselager sits down with Dr. Alexander Grinberg, one of the few physicians who has worked with peptide therapeutics since the 1980s.
    Long before peptides became a social media trend, Dr. Grinberg was involved in clinical research using peptide bioregulators in patients with autoimmune disease, immune dysfunction, radiation exposure, viral illnesses, and regenerative medicine. Drawing on more than 35 years of clinical and scientific experience, he explains what peptides can realistically do, where the evidence is strongest, and why personalized medicine matters far more than following influencer protocols.

    They discuss the biggest mistakes people make when self-experimenting with peptides, why proper diagnostics are essential before starting treatment, cancer considerations, mitochondrial health, immune function, bioregulators, GLP-1 medications, and what the future of peptide medicine may look like.

    Whether you're curious about BPC-157, GHK-Cu, Epitalon, MOTS-c, SS-31, or simply want to separate scientific evidence from marketing hype, this conversation offers one of the most balanced and informative discussions on peptides available today.

    In this episode you'll learn:
    Why peptides are far more powerful than most people realize
    The biggest risks of self-prescribing peptide protocols
    Who should avoid certain peptides altogether
    The blood tests and biomarkers to check before starting
    Why longevity treatments should always be personalized
    The fascinating history of peptide medicine dating back to the 1980s
    How peptides may support healthy aging, immune health and regenerative medicine
    The future of peptide therapeutics and precision longevity medicine

    Timestamps
    00:00 Introduction
    01:18 Why peptides need to be treated like real medicines
    03:30 Blood tests and biomarkers before using peptides
    05:45 Cancer risks, contraindications and safety
    07:25 How Dr. Grinberg became one of the first peptide physicians
    12:10 The history of peptide research in the Soviet Union
    13:15 Personalized peptide medicine explained
    19:20 The dangers of self-experimenting with peptides
    20:00 Growth hormone peptides and cancer concerns
    22:00 How physicians evaluate peptide protocols
    25:00 Bioregulators vs modern peptides
    30:00 Autoimmune disease and peptide therapies
    36:00 Mitochondrial peptides and healthy aging
    42:00 GLP-1 peptides beyond weight loss
    48:00 The future of peptide medicine
    55:00 Final thoughts

    If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in longevity, regenerative medicine, and evidence-based health optimization.
    Connect with Claudia von Boeselager
    Website: https://llinsider.com
    Newsletter: https://llinsider.com/newsletter
    Follow the Longevity & Lifestyle Podcast for weekly conversations with the world's leading experts in longevity, health optimization, and performance.
    #Longevity #Peptides #Biohacking #HealthyAging #PrecisionMedicine
  • The Longevity & Lifestyle Podcast

    #254 Roger Love — Your Voice Is Shaping Your Life: Confidence, Authenticity & Human Connection

    19/06/2026 | 51 mins.
    My guest today is Roger Love - one of the world’s most renowned voice coaches. He has worked with top performers, executives, actors, and public figures, and his work sits at the intersection of voice, confidence, emotional expression, breath, nervous system regulation, communication, and identity. In this conversation, we explore how the way you sound shapes the way people perceive you and the way you perceive yourself.

    We get into Roger’s framework for mastering the five core voice variables — pitch, pace, tone, melody, and volume — and why most people unknowingly sound monotone, anxious, apologetic, or less confident than they really are.

    He explains how voice patterns influence emotion, why public speaking fear is really fear of judgment, and how changing the sounds of confidence can actually help build confidence in real life.

    We also discuss the connection between voice and longevity, Roger’s work using singing and airflow to help people with stuttering and post-stroke speech challenges, and why he believes your voice may be one of the most overlooked tools for improving relationships, self-expression, business, and quality of life.

    This episode is for anyone who wants to communicate with more clarity, warmth, authority, and authenticity.

    Timestamps
    00:00 Why your voice may be shaping your entire life
    00:59 Intro to Roger Love and why voice matters beyond performance
    02:54 Roger’s origin story — singing, happiness, and becoming a voice coach at 16
    08:02 The 5 core voice variables: pitch, pace, tone, melody, and volume
    09:50 How emotion shapes the way you should speak — fast vs. slow, loud vs. soft
    11:18 Why people remember how you make them feel more than the words you say
    16:00 Why monotone voices lose people — and how melody creates engagement
    19:23 The “leading tone” technique to keep people listening and prevent interruptions
    20:02 How vocal musicality creates emotion, attention, and connection
    21:20 Voice, relationships, and longevity — Roger’s perspective on why communication keeps us young
    23:14 Roger’s documentary Find Your Voice and the story of helping a lifelong stutterer
    25:23 “Solid airflow” and Roger’s approach to stuttering and speech transformation
    26:12 Singing, stroke recovery, and helping his mother speak again
    27:32 Why public speaking fear is really fear of being judged
    28:52 “The sound creates the reality” — how confident speech builds real confidence
    46:32 Why voice is a learnable skill, not a fixed trait
    47:34 Why nobody is stuck with the voice they have
    49:37 The voice makeover idea that could change your life

    #RogerLove #CommunicationSkills #PublicSpeaking #Confidence
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About The Longevity & Lifestyle Podcast
Claudia von Boeselager is here to empower you to live at your best and reach your highest potential by sharing groundbreaking strategies, tools, and practices for your longevity and lifestyle from the world’s pioneering experts. For more, visit: LLinsider.com Welcome to The Longevity & Lifestyle Podcast! Claudia is on a mission to help 1 billion people optimize their lives and reach their fullest potential so that they can make a positive impact in the world! Tune in to learn how to increase your healthspan, improve the quality of your life and lifestyle also around entrepreneurship, managing personal finances and investing, and much more. Topics include how to optimize your health in areas such as sleep, nutrition, cognition, metabolic health, reversing diabetes, intermittent fasting, biomarkers, gut health, hormones, the female biorhythm, skin, hair, biohacking tips, supplements, mastering your mindset, improve your relationships and overall happiness, meditation, how to perform better in business, optimize your daily routines, achieve peak performance, biohacking your age, and more. Claudia is a Peak Performance Coach and Serial Entrepreneur passionate about helping you thrive in all areas of your life & business! She knows what it’s like to feel close to burnout and not be at your best. Thanks to 10+ years of research, countless interviews with global pioneers, and hundreds of thousands spent, she continues to uncover how you, too, can achieve peak performance to live your life at its best - all while having lots of fun! So make sure to TUNE IN and start living the best version of yourself!
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