A deep, unfiltered conversation with master cultivator Quentin Di Costanzo on genetics, living systems, and why working with plants demands humility, responsibility, and long-term vision rather than extraction and scale.
Quentin Di Costanzo is a master cultivator and internationally recognized expert in cannabis genetics, with more than 15 years of experience across pharmaceutical, medical, and recreational contexts. He is the founder of Aficionado French Connection and a partner of Aficionado Humboldt, having led cultivation and genetic research projects in the United States, Canada, Colombia, Turkey, and Portugal.
Formally trained in horticulture with a specialization in tissue culture and plant breeding, Quentin combines scientific rigor with a deep respect for ancestral and land-based knowledge. His work has taken him to remote regions of Africa, the Himalayas, and South America, where he has studied, collected, and helped preserve rare landrace genetics under ethical conservation frameworks.
Key topics in this episode:
- Growing up with plants, animals, and ecosystems as teachers
- Cultivation as a lifelong path rather than an industrial process
- The limits of modern agriculture and genetic optimization
- Living genetics, landraces, and biodiversity preservation
- The difference between controlling plants and collaborating with them
- Ethics, responsibility, and long-term stewardship in plant medicine
- Parallels between plant intelligence, traditional knowledge, and Bwiti principles
Quentin reflects on how his early fascination with reptiles, forests, and living systems shaped his understanding of cultivation as a dialogue rather than a domination. He explains why many industrial agricultural models fail: they prioritize yield, uniformity, and speed at the expense of resilience, diversity, and ecological balance.
Together with Raphael Nicolle, the conversation explores how true genetic work requires patience, deep observation, and respect for time scales that exceed human timelines. Quentin shares why landrace preservation is not nostalgia, but a critical response to genetic erosion driven by globalized markets.
The discussion also draws strong parallels between plant cultivation and traditional spiritual systems: both require lineage, transmission, and responsibility. Just as Bwiti cannot be reduced to a technique or product, living plants cannot be reduced to isolated molecules or traits without losing something essential.
“When you reduce a plant to a molecule, you stop working with life. You start working against it.”
At the Iboga Leadership Summit, Quentin Di Costanzo will bring a rare, grounded voice on cultivation, biodiversity, and ethics. His contribution will focus on how to protect living genetic heritage while navigating scientific research, modern agriculture, and global demand — without repeating extractive patterns that have already damaged countless plant lineages.
The Iboga Leadership Summit is hosted by Moughenda and the Bwiti community in Gabon, for physicians, pharmacists and providers, neuroscience researchers, farmers and agricultural technicians, students and community leaders, lawyers, policymakers and environmentalists — and everybody called to Bwiti, Ibogaine and Iboga.
21–24 June, Libreville, Gabon
Details and tickets:
www.ibogaleadershipsummit.com