018 BCMA Bispecific antibodies - Novel immunotherapies for relapsed myeloma
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
This episode explores bispecific antibodies — how they work, the benefits they bring, and the key side effects patients and carers need to know about.
📌Key Takeaways:
Bispecific antibodies ‘wake up’ your immune system to fight myeloma — and response rates are higher than ever before.
Early side effects (like fever or low blood pressure) usually settle quickly with the right care.
Infections are the main long-term risk — but regular antibody infusions and vigilance make treatment much safer.
This podcast is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for personalised medical guidance regarding your health concerns
ABOUT YOUR HOSTS
Dr. Jam Kothari
Dr Jam Kothari (@myeloma_medic) is an Oxford based blood cancer doctor, specialising in the treatment of multiple myeloma and associated conditions. He has been a consultant for a decade, and leads the provision of myeloma care for Oxford and neighbouring areas. He lectures regionally and nationally and leads clinical trials investigating the use of new treatments for myeloma. He is a strong believer in patient based, holistic care, delivered with warmth, clarity and integrity.
Dr. Sally Moore
Dr Sally Moore is a Bristol based consultant who specialises in treating patients living with multiple myeloma and other plasma cell disorders. She oversees the delivery of clinical research studies for myeloma patients and has academic interests in how to maximise quality of life for patients and improve outcomes in older, less fit patients. She frequently contributes to myeloma related educational events for fellow doctors and healthcare professionals at a local, regional and national level and is an active member of the UK Myeloma Research Alliance and an executive member of the UK Myeloma Society.
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40:48
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40:48
017 The Myeloma Transplant Journey: A Nurse’s Guide to What Really Happens
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
Specialist nurse Alex Scott walks patients and carers through every step of the autologous stem cell transplant process, from preparation to recovery, with clarity, compassion, and practical advice.
📌Key Takeaways:
It’s not just medical – emotional and practical support is essential to navigating a transplant.
From ice lollies to PICC lines, every detail is planned to keep you safe and supported.
Transplants can be tough – but knowing what to expect makes all the difference.
This podcast is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for personalised medical guidance regarding your health concerns
ABOUT YOUR HOSTS
Dr. Jam Kothari
Dr Jam Kothari (@myeloma_medic) is an Oxford based blood cancer doctor, specialising in the treatment of multiple myeloma and associated conditions. He has been a consultant for a decade, and leads the provision of myeloma care for Oxford and neighbouring areas. He lectures regionally and nationally and leads clinical trials investigating the use of new treatments for myeloma. He is a strong believer in patient based, holistic care, delivered with warmth, clarity and integrity.
Dr. Sally Moore
Dr Sally Moore is a Bristol based consultant who specialises in treating patients living with multiple myeloma and other plasma cell disorders. She oversees the delivery of clinical research studies for myeloma patients and has academic interests in how to maximise quality of life for patients and improve outcomes in older, less fit patients. She frequently contributes to myeloma related educational events for fellow doctors and healthcare professionals at a local, regional and national level and is an active member of the UK Myeloma Research Alliance and an executive member of the UK Myeloma Society.
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54:35
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54:35
016 Life After Transplant: Maintenance Treatment in Myeloma Care
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
This episode explores what happens after a stem cell transplant in multiple myeloma, focusing on consolidation and maintenance treatments - especially the use of lenalidomide - and how these therapies aim to sustain remission and quality of life.
📌Key Takeaways:
Maintenance therapy isn't just more treatment - it's your path to a longer, better-quality remission.
Side effects like diarrhoea and cramps are common - but manageable, and shouldn't be suffered in silence.
A future with shorter or even time-limited maintenance might be closer than you think.
This podcast is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for personalised medical guidance regarding your health concerns
ABOUT YOUR HOSTS
Dr. Jam Kothari
Dr Jam Kothari (@myeloma_medic) is an Oxford based blood cancer doctor, specialising in the treatment of multiple myeloma and associated conditions. He has been a consultant for a decade, and leads the provision of myeloma care for Oxford and neighbouring areas. He lectures regionally and nationally and leads clinical trials investigating the use of new treatments for myeloma. He is a strong believer in patient based, holistic care, delivered with warmth, clarity and integrity.
Dr. Sally Moore
Dr Sally Moore is a Bristol based consultant who specialises in treating patients living with multiple myeloma and other plasma cell disorders. She oversees the delivery of clinical research studies for myeloma patients and has academic interests in how to maximise quality of life for patients and improve outcomes in older, less fit patients. She frequently contributes to myeloma related educational events for fellow doctors and healthcare professionals at a local, regional and national level and is an active member of the UK Myeloma Research Alliance and an executive member of the UK Myeloma Society.
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33:59
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33:59
015 Inside the Transplant: What to Expect from an Autologous Stem Cell Transplant
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
This episode walks you through every stage of an autologous stem cell transplant for myeloma - from preparation and chemotherapy to recovery and going home.
📌Key Takeaways:
You’ll get high-dose chemotherapy (melphalan) followed by your own stem cells - not someone else’s.
Expect a tough week of diarrhoea, fatigue and infection risk - but recovery does come.
From ice lollies to sweetcorn smells, it’s a challenging but proven path to deeper remission.
This podcast is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for personalised medical guidance regarding your health concerns
ABOUT YOUR HOSTS
Dr. Jam Kothari
Dr Jam Kothari (@myeloma_medic) is an Oxford based blood cancer doctor, specialising in the treatment of multiple myeloma and associated conditions. He has been a consultant for a decade, and leads the provision of myeloma care for Oxford and neighbouring areas. He lectures regionally and nationally and leads clinical trials investigating the use of new treatments for myeloma. He is a strong believer in patient based, holistic care, delivered with warmth, clarity and integrity.
Dr. Sally Moore
Dr Sally Moore is a Bristol based consultant who specialises in treating patients living with multiple myeloma and other plasma cell disorders. She oversees the delivery of clinical research studies for myeloma patients and has academic interests in how to maximise quality of life for patients and improve outcomes in older, less fit patients. She frequently contributes to myeloma related educational events for fellow doctors and healthcare professionals at a local, regional and national level and is an active member of the UK Myeloma Research Alliance and an executive member of the UK Myeloma Society.
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35:34
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35:34
014 Stem cells : what they are, mobilisation and collection.
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
During this episode, Jam & Sally give an in-depth, patient-friendly guide to stem cell mobilisation - the essential step before undergoing an autologous stem cell transplant for multiple myeloma.
📌Key Takeaways:
Stem cells are collected from your blood - not your bone marrow - thanks to clever modern techniques.
Daily injections (GCSF) help ‘mobilise’ these vital parent cells for collection and storage.
Most people collect enough cells for transplant in just one or two days - with minimal discomfort.
This podcast is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for personalised medical guidance regarding your health concerns
ABOUT YOUR HOSTS
Dr. Jam Kothari
Dr Jam Kothari (@myeloma_medic) is an Oxford based blood cancer doctor, specialising in the treatment of multiple myeloma and associated conditions. He has been a consultant for a decade, and leads the provision of myeloma care for Oxford and neighbouring areas. He lectures regionally and nationally and leads clinical trials investigating the use of new treatments for myeloma. He is a strong believer in patient based, holistic care, delivered with warmth, clarity and integrity.
Dr. Sally Moore
Dr Sally Moore is a Bristol based consultant who specialises in treating patients living with multiple myeloma and other plasma cell disorders. She oversees the delivery of clinical research studies for myeloma patients and has academic interests in how to maximise quality of life for patients and improve outcomes in older, less fit patients. She frequently contributes to myeloma related educational events for fellow doctors and healthcare professionals at a local, regional and national level and is an active member of the UK Myeloma Research Alliance and an executive member of the UK Myeloma Society.
New Zealand