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Dhru Purohit Show

Podcast Dhru Purohit Show
Dhru Purohit
Hi, I'm Dhru (like Drew), and every week, I interview the top experts in health, medicine, and mindset to provide you with in-depth, step-by-step protocols to t...

Available Episodes

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  • Supercharge Your Sleep and Improve Your Longevity Using the Power of Intermittent Fasting & Circadian Biology (Rebroadcast)
    This episode is brought to you by  Bon Charge and Momentous. We used to think circadian rhythm only applied to sleep. But emerging science has revealed a link between our circadian rhythm and metabolism, cognition, risk for chronic diseases, and many other crucial aspects of our health. Our biology was designed to live in sync with a natural light-dark cycle, but modern-day society has disrupted this natural balance.  Today on The Dhru Purohit Show, we’re revisiting one of our favorite episodes with Dr. Satchin Panda. Dr. Panda dives deep into his groundbreaking circadian biology research and shares how leveraging your circadian rhythm can dramatically improve your sleep, lower your risk of chronic disease, and improve your cognitive function. They also discuss how time-restricted eating, exercise, and light can be used to help program your circadian rhythm and why it’s especially important for shift workers to take advantage of these tools.  Dr. Panda is pioneering circadian biology research. He is a professor at the Salk Institute for Biological Studies, a Pew Biomedical Scholar, founder of the UC San Diego Center for Circadian Biology, and recipient of the Julie Martin Mid-Career Award in Aging Research. Dr. Panda has spoken at conferences around the world about his work on circadian rhythms and diabetes, including Diabetes UK, the American Diabetes Association, the Danish Diabetes Association, and the professional diabetes societies of Europe and Australia. In this episode, Dhru and Dr. Panda dive into: Why late-night eating is so detrimental to our health (2:15) Organ systems that have a circadian rhythm (8:24) Common ailments that could be related to circadian rhythm disturbances (14:11) Night-shift work and cancer risk (20:19) How poor sleep perpetuates bad food choices (27:00) What happens in the body when you rely on an alarm clock (44:01) Why you need to accumulate sleep debt for better sleep (51:25) Time-restricted eating and sleep (1:00:40) How to combat fragmented sleep (1:15:35) The best time to work out (1:55:50) The link between exercise and cancer (2:07:55) Positive changes for better sleep health on a global scale (2:17:20) Strategies for night-shift workers to combat circadian rhythm disruption 02:45:10) Dr. Panda’s research in firefighters (2:48:46) Tips for optimizing your circadian rhythm (3:14:20) Where to follow and support Dr. Panda's work (3:27:50) Also mentioned in this episode: The Circadian Code: Lose Weight, Supercharge Your Energy, and Transform Your Health from Morning to Midnight The Circadian Diabetes Code: Discover the Right Time to Eat, Sleep, and Exercise to Prevent and Reverse Prediabetes and Diabetes Download the MyCircadianClock app Try This: 6 Crazy Facts About Sleep Try This: How Exercise Helps Fight Cancer For more on Dr. Satchin Panda, follow him on Twitter @SatchinPanda, Instagram @satchin.panda, or his Website. This episode is brought to you by Bon Charge and Momentous. Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Go to livemomentous.com and enter promo code DHRU to get 20% off any order.  Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • Don't Let The Scale Run Your Life: The Power of Focusing on Body Composition
    This episode is brought to you by Fatty15 and Blueland. When it comes to weight loss, most people rely on the usual strategies—cutting calories and exercising more. But what happens when these methods don’t work? And how do we ensure we’re losing fat, not muscle? It’s time to rethink our approach. Instead of just focusing on the number on the scale, we should prioritize body recomposition—building a stronger, healthier body that supports longevity and resilience as we age. Today on The Dhru Purohit Show, we bring you a special compilation episode featuring Dhru's conversations with leading experts on why body composition is more important than your scale weight.  Sal Di Stefano, Mind Pump co-founder and fitness expert, explains why body composition matters more than the number on the scale. He breaks down the most efficient and sustainable ways to exercise and highlights the crucial role muscle plays in overall health. Sal also reveals why lasting motivation for a healthier lifestyle must come from within. By adopting practical, sustainable strategies, we can boost energy, improve well-being, and achieve our fitness goals—all while promoting longevity. JJ Virgin shares her top strategies for weight loss, muscle building, and vibrant aging, emphasizing the power of resistance training for sustained fat loss and the importance of tracking personal goals for long-term motivation. Sal Di Stefano began his fitness journey at just 18, quickly rising to prominence as a trainer and opening some of the largest big-box gyms in the California Bay Area. By 24, he launched a wellness-focused fitness studio that combined expertise in hormones, nutrition, gut health, and fitness training. Today, Sal is a highly sought-after expert known for his practical, easy-to-apply insights. As co-host of the Mind Pump Podcast—the world’s top fitness and health podcast—he’s appeared on hundreds of leading shows and frequently speaks at events for trainers and health practitioners. JJ Virgin is a renowned health and fitness expert, bestselling author, and prominent media personality. With over three decades of experience in the field, she has become a trusted authority in nutrition, weight loss, and wellness. She is the author of four New York Times bestsellers. Virgin actively contributes to the health and wellness community through speaking engagements, online programs, and her podcast, Well Beyond 40.  In this episode, Dhru and his guests dive into: Why weight loss matters less than body composition (1:08) Reframing our approach to exercise and the body's adaptation to fitness (12:41) Hacks to help with fat loss versus weight loss (22:43) Tracking movement and progress (26:10) Testing body composition and the importance of prevention (29:27) Tracking food intake to optimize protein, fiber, and sleep quality (33:09) Aging powerfully and the new normal (44:01) The misconception about bulking up and the reality of muscle building (47:56) Also mentioned: Full episode with Sal Di Stefano Full episode with JJ Virgin Virginia MacColl Oldest Ninja Warrior episode This episode is brought to you by Fatty15 and Blueland. Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. Get a clean home while keeping a clean planet with Blueland. Right now, get 15% off your first order by going to blueland.com/dhru. Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • Step Out of Fear and Hive Mindset and Into Nuanced, Free Thinking with Kaizen Asiedu
    This episode is brought to you by Cozy Earth, Manukora Honey, and Aqua Tru. Political and social discussions have become increasingly divisive today, often leaving little room for nuance or open dialogue. Differing viewpoints are frequently shut down, met with hostility, or dismissed outright, despite the fact that real growth comes from curiosity and engaging with opposing perspectives. Today’s guest joins us to explore the courage it takes to question our beliefs, understand where they come from, and embrace complexity in a world that often demands rigid certainty. Today on The Dhru Purohit Show, Dhru sits down with cultural commentator Kaizen Asiedu to explore the importance of understanding our beliefs, where they come from, and the courage it takes to question them. Kaizen shares his personal journey of challenging lifelong beliefs and embracing alternative perspectives. He also discusses how this willingness to question ideas is often missing in today’s political climate, where fear of dissent has led to tribalism and dehumanization. Additionally, he shares his insights on the MAHA movement, health and wellness discussions, and the concept of antifragility. Kaizen Asiedu is a cultural commentator dedicated to empowering people by simplifying complex political and social issues into messages that leave listeners informed and appreciative of nuance. After earning a philosophy degree from Harvard, he entered the gaming industry, ultimately becoming Head of Global Esports Events at Riot Games. While leading the League of Legends World Championship and winning an Emmy, he felt a growing restlessness—a desire for a deeper, more personal purpose. Today, he helps high achievers who feel burnt out or lost transition from unfulfilling careers to meaningful work, whether as entrepreneurs or in roles that excite them as much as playing their favorite game or reading a beloved book. In this episode, Dhru and Kaizen dive into: Recognizing that you are in the “Matrix” of living a life expected of you (00:00:25) The ideas Kaizen was called to question (2:50) Fear-based conditioning and morality (7:40) RFK’s confirmation hearing and steelmanning concerns about his positions (20:20) The discouragement of open conversations and the rise of cancel culture (30:10) The rejection of humanity and the divisions it has caused (40:36) Red flags that indicate we are stuck in tribalism (44:36) Kaizen’s views that diverge from the current administration (47:46) Kaizen’s personal journey and the significance of "kaizen" in Japanese culture (54:16) The role of psychedelics, mindfulness, and shifting belief systems (58:56) Engaging with people as they are in the present moment (01:07:46) The intersection of lifestyle choices and systemic issues (01:14:46) Respecting alternative viewpoints, embracing different perspectives, and the concept of antifragility (01:19:16) Final thoughts (01:34:46) For more on Kaizen, follow him on Instagram, X/Twitter, TikTok, and YouTube. This episode is brought to you by Cozy Earth, Manukora Honey, and Aqua Tru. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP. Upgrade to the creamiest honey, packed with antioxidants and prebiotics. Just go to manukora.com/dhru to get $25 off the Starter Kit and boost your energy, immunity, and digestive health today! AquaTru is a countertop reverse osmosis purifier with a four-stage filtration system that removes 15x more contaminants than the bestselling water filters out there. Go to dhrupurohit.com/filter/ and get $100 off when you try AquaTru for yourself.  Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • Having Low Levels of this Miracle Molecule Puts You At Risk of a Heart Attack. The Best and Worst Habits to Increase Nitric Oxide Production with Dr. Nathan Bryan
    This episode is brought to you by Levels and Fatty15. When we think about long-term health and longevity, nitric oxide production probably isn’t the first thing that comes to mind. But today’s guest explains why this crucial molecule plays a key role in our bodies—and the tell-tale signs of low production that can ultimately contribute to chronic disease. Today on The Dhru Purohit Show, Dhru sits down with Dr. Nathan Bryan to explore why nitric oxide is the holy grail of molecules for long-term health—and the top lifestyle factors that can make or break its production. Dr. Bryan ranks the biggest disruptors of nitric oxide, including alcohol, poor sleep, a sedentary lifestyle, ultra-processed foods, and chronic stress, and dives into the latest research on how they impact your body. He also breaks down the critical role nitric oxide plays in disease prevention, from chronic illness to Alzheimer’s. If you’re looking for a masterclass on how to boost nitric oxide production and what habits you need to tweak, this episode is a must-listen. Dr. Nathan Bryan is a renowned biomedical researcher known for his groundbreaking work on nitric oxide (NO) biology. Dr. Bryan's research has significantly advanced our understanding of NO's critical roles in cardiovascular health, immune function, and neurobiology. Beyond academia, he advocates for public health, translating his research into practical solutions for improving human health. His new book is The Secret of Nitric Oxide.  In this episode, Dhru and Dr. Bryan dive into: How alcohol impacts nitric oxide production (00:31) Why nitric oxide is crucial for health (03:12) The dangers of nicotine and smoking on nitric oxide (04:36) The controversy around seed oils (10:17) How dangerous are ultra-processed foods (18:43) How nitric oxide is created and what chronic stress does to production (26:10) Sedentary lifestyle and its impact on health risks (33:39) Nightly desserts and glucose monitoring (42:10) Intermittent fasting and the importance of meal personalization (50:15) Antiseptic mouthwash, bad breath, and the microbiome (54:09) Nitric oxide benchmarks and what test strips measure (58:50) Lack of optimal sun exposure (01:11:57) Eating nitrate-rich foods and carnivore diet concerns (01:15:14) Hydration’s role in nitric oxide levels (01:21:27) Ibuprofen, inflammation, and nitric oxide (01:23:11) N101 products and final thoughts (01:29:22) Also mentioned in this episode: Dr. Nathan Bryan’s book - The Secret of Nitric Oxide https://www.n101nutrition.com/ Try This-Firefighter Study For more on Dr. Nathan, follow him on Facebook, Instagram, X/Twitter, YouTube, and his Website. This episode is brought to you by Levels and Fatty15. Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link, levels.link/DHRU. Make moves on your metabolic health with Levels today.  Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • A Silent But Deadly Killer: How Poor Air Quality is a Driver of Chronic Disease and What We Can Do to Protect Ourselves Now
    This episode is brought to you by BiOptimizers, Bon Charge, and Maui Nui. Every year, seven million people die prematurely due to poor air quality. While it may not be obvious, the air we breathe directly impacts our health—contributing to allergies, autoimmune conditions, lung diseases, and even neurodegenerative disorders. Today’s guest joins us to explain why air quality should be a key part of the conversation on toxin exposure and how to reduce our risk of toxic air. Today on The Dhru Purohit Show, Dhru sits down with Dr. Elroy Vojdani to discuss the critical link between air quality and the rise in severe health conditions. Dr. Vojdani explains why air quality isn’t discussed enough, how to monitor it, and how to adjust your daily activities accordingly. He also breaks down the best ways to support detoxification, the top supplements for recovering from toxin exposure, and practical tips for improving indoor air quality at home and in the office. In this episode, Dhru and Dr. Elroy Vojdani dive into: The conditions linked to poor air quality (00:28) Why air quality isn’t widely discussed—and what makes it so harmful (02:17) The link between diagnosis and uncovering the true cause of toxin exposure (09:25) Key fundamentals to minimize exposure (12:46) How to measure and monitor air quality to adjust daily activities (15:51) How poor air quality can contribute to autoimmune conditions (30:01) The after-effects of the LA fires and essential precautions (38:34) The connection between hearing loss and Alzheimer’s risk (45:29) How Bryan Johnson’s trip to India sparked a conversation about air quality (50:49) Evidence-based supplements for detoxification and the role of sweating (52:49) Avoiding misinformation and a ‘doom and gloom’ mentality (58:22) Why outdoor air is often cleaner than indoor air (1:02:22) Dr. Elroy’s advice on advocating for air filters in schools (1:04:32) Final thoughts (1:05:44) Also mentioned in this episode: Atmo Air Monitor Aware Indoor Air Quality Monitor Nithin Kamath with Bryan Johnson viral video AquaTru and Air Doctor Filters  IQ Air  Freakanomics Air Quality Podcast Dr. Elroy’s book - When Food Bites Back: Taking Control of Autoimmune Disease For more on Dr. Elroy, follow him on Instagram, Facebook, X/Twitter, YouTube, and his Website. This episode is brought to you by BiOptimizers, Bon Charge, and Maui Nui. Go to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order of Sleep Breakthrough and find out this month’s gift with purchase.  Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Right now, Maui Nui Venison is offering my community 15% off your first purchase. Just go to mauinuivenison.com/DHRU or enter the code DHRU at checkout to get 15% off and up your high-quality protein today. Offer ends 2/28/2025.  Learn more about your ad choices. Visit megaphone.fm/adchoices
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About Dhru Purohit Show

Hi, I'm Dhru (like Drew), and every week, I interview the top experts in health, medicine, and mindset to provide you with in-depth, step-by-step protocols to take your health to the next level.
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