Huberman Lab

In this Huberman Lab Essentials episode, my guest is Dr. Casey Halpern, MD, a professor of neurosurgery at the Perelman School of Medicine at the University of Pennsylvania. We discuss how deep brain stimulation and other neuromodulation approaches are being used to treat Parkinson's disease, obsessive-compulsive disorder (OCD), binge eating disorder and depression-related symptoms. We also explore the brain circuits that drive compulsions, cravings and impulsivity, as well as emerging non-invasive tools for predicting and treating harmful behaviors.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

Function: https://functionhealth.com/huberman

Rorra: https://rorra.com.huberman

Timestamps

(00:00:00) Casey Halpern

(00:00:20) Neurosurgery, Deep Brain Stimulation

(00:04:19) Obsessive-Compulsive Disorder (OCD) & Treatments

(00:10:11) Sponsor: Function

(00:11:49) OCD Brain Areas, Addiction

(00:14:12) Nucleus Accumbens, Risk & Rewards; Binge Eating Disorder

(00:18:28) Sponsor: AG1

(00:19:46) Non-Invasive Brain Stimulation, Transcranial Magnetic Stimulation

(00:27:31) Sponsor: Rorra

(00:28:46) Awareness of Cravings, Severe Binge Eating Disorder

(00:32:51) Artificial Intelligence/Machine Learning & Predicting Impulsive Behavior

(00:36:57) Acknowledgements

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Dr. Paul Conti, MD, is a board-certified psychiatrist and an expert in how to improve mental health and increase your sense of agency and wellbeing. He is also an expert in trauma treatment. We discuss practical tools you can use to gain insight into your natural strengths and to make better life choices on your own behalf. We explore how these tools can help overcome low motivation, intrusive thoughts and self-destructive bad habits. We also discuss how to balance internal reflection and external action to ensure you move your life forward in the right directions.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

Helix Sleep: https://helixsleep.com/huberman

BetterHelp: https://betterhelp.com/huberman

Function: https://functionhealth.com/huberman

Rorra: https://rorra.com/huberman

Timestamps

(00:00:00) Paul Conti

(00:02:51) Self View; Tool: What's Going Right?; State Dependence

(00:10:03) Sponsors: Helix Sleep & BetterHelp

(00:12:44) Tool: Compassionate Curiosity; Falseness; Social Media

(00:21:00) Doing vs Thinking; Self-Reflection

(00:29:55) External vs Internal Processing, Balance

(00:40:42) Sponsor: AG1

(00:42:26) Quiet vs Verbal; Questions to Learn About Self

(00:53:17) Examined Life & Reflection; Changing Unwanted Behavior

(01:02:54) Making Positive Changes, Problem Solving

(01:07:26) Sponsor: Function

(01:09:03) Behavior Pattern Insight & Reclaiming Agency

(01:17:06) Agency & Control; Getting in Your Own Way

(01:22:49) Trauma, Living Intentionally; Internal Turmoil

(01:29:08) Intrusive Thoughts, Tool: Self Talk Awareness; Dreams

(01:34:10) Sponsor: Rorra

(01:35:23) Trauma & Emotions; Healing Childhood Trauma

(01:43:32) Photographs, Positive Climate for the Mind; Spirituality, Good & Evil

(01:52:53) Happiness & Expectations; Death, Living a Good Life

(02:03:10) Book Writing; Acknowledgements

(02:07:25) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

Disclaimer & Disclosures
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In this Huberman Lab Essentials episode, I explain how the body senses and uses sugar, and why understanding those mechanisms can help reduce sugar cravings. I discuss different types of sugar and how they are processed by pathways in the gut and the brain to shape appetite and the desire for specific foods. I also share many science-based tools to help curb sugar cravings and support healthy blood sugar regulation.

Read the show notes at hubermanlab.com.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

Lingo: https://hellolingo.com/huberman

LMNT: https://drinklmnt.com/huberman

Timestamps

(00:00:00) Sugar

(00:00:37) Hunger, Hormones & Blood Glucose

(00:03:03) Fructose vs Glucose, Controlling Hunger

(00:06:30) Sponsor: AG1

(00:07:54) Brain Circuits: Sweet Taste & Nutritive Pathways

(00:10:51) Sweet Taste & Dopamine

(00:13:22) Gut & Blood Glucose; Tool: Sugar Cravings & Hidden Sugars

(00:15:44) Sponsor: Lingo

(00:16:53) Glycemic Index, Tool: Food Choices, Fiber & Sugar Intake

(00:20:55) Glutamine Supplementation, Leaky Gut & Sugar Cravings

(00:23:17) Tool: Lemon Juice to Blunt Blood Glucose

(00:26:44) Sponsor: LMNT

(00:28:16) Tool: Reduce Blood Sugar Cravings with Cinnamon

(00:29:10) Berberine & Potent Molecules to Regulate Blood Glucose

(00:30:52) Tool: Quality Sleep & Sugar Cravings

Disclaimer & Disclosures
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Scott Galloway is a professor of marketing at New York University's Stern School of Business. We discuss masculine roles and obligations of past, present and future. We explore which are timeless and which are changing, and positive steps boys and men can take to create meaning and stability in their lives. We cover work, finances, health and relationships to build a grounded, purposeful life. We also discuss tech, social media, alcohol, cannabis and porn. Throughout, we emphasize specific daily practices for building mental, physical and economic resilience, compassion for others, and for navigating key life decisions in every realm.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

David: https://davidprotein.com/huberman

Wealthfront*: https://wealthfront.com/huberman

Function: https://functionhealth.com/huberman

LMNT: https://drinklmnt.com/huberman

Timestamps

(00:00:00) Scott Galloway

(00:02:45) Mentoring Young Men

(00:06:16) Positive Masculinity Defined

(00:13:37) Sponsors: David & Wealthfront

(00:16:33) Men & Goals, Role Models, Technology; Relationships

(00:26:34) Elon Musk; Big Tech

(00:31:53) Varying Role Models, Flaws; Criticism, Big Tech & Incendiary Content

(00:43:33) Sponsor: AG1

(00:44:57) Fear, Dating & Rejection, Relationship Dynamics

(00:53:39) Social Media Impacts on Kids; Regulation

(01:06:03) Phone, Dopamine & Pseudo-OCD; Solutions

(01:14:03) Sponsor: Function

(01:15:14) Naval Academy & Lifestyle Protocols, Mandatory National Service

(01:23:08) Alcohol Phones & Professional Considerations

(01:33:43) Drinking Age; Cannabis, THC

(01:37:16) Sponsor: LMNT

(01:38:36) Cannabis; Porn, Addiction

(01:46:14) Anger; Testosterone; Aspirational Masculinity, Toxic Femininity

(01:56:25) Advocating for Young Men, Economic Opportunity, Gerontocracy

(02:04:43) Generation Gaps, Retirement, "Vampire" Generation

(02:10:30) Bet on Unremarkable, Universities & Vocations; Gerontocracy

(02:18:48) Aging; Paying it Forward & Male Mentorship

(02:25:33) Seeking Mentors, Young Men; Acknowledgments

(02:33:13) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

*This experience may not be representative of other Wealthfront clients, and there is no guarantee of future performance or success. Experiences will vary. Andrew Huberman receives cash compensation from Wealthfront Brokerage for paid testimonials in his podcast, creating a conflict of interest. The Cash Account, which is not a deposit account, is offered by Wealthfront Brokerage LLC, member FINRA/SIPC.  Wealthfront Brokerage is not a bank. The base APY is 3.30% on cash deposits as of January 30, 2026, is representative, subject to change, and requires no minimum. If eligible for the overall boosted rate of 4.05% offered in connection with this promo, your boosted rate is also subject to change if the base rate decreases during the 3 month promo period. Additional terms and conditions apply, which can be found on Wealthfront.com/Huberman.  Funds in the Cash Account are swept to program banks, where it earns the variable APY. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Investment advisory services are provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, bank-guaranteed or FDIC-insured, and may lose value.

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In this Huberman Lab Essentials episode, my guest is Dr. Erich Jarvis, PhD, a professor and Head of the Laboratory of Neurogenetics of Language at Rockefeller University and an investigator at the Howard Hughes Medical Institute (HHMI). We discuss the brain circuits and genes underlying spoken language and why the ability to learn and produce vocalizations is extraordinarily rare in the animal kingdom. We also explore why song likely evolved before language, how gesture and movement share deep neural roots with speech, the neurobiology of stuttering, why childhood is the optimal window for language acquisition, and how physical movement — including dance — may help preserve speech and cognitive function across a lifetime.

Read the show notes at hubermanlab.com.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

Function: https://functionhealth.com/huberman

Eight Sleep: https://eightsleep.com/huberman

Timestamps

(00:00:00) Speech & Language

(00:00:23) Speech vs. Language; Brain Pathways for Communication

(00:01:57) Gesture, Hand Movement & Speech Evolution

(00:04:31) Sponsor: Function

(00:05:59) Innate Vocalizations vs. Learned Speech

(00:08:01) Evolution of Spoken Language; Neanderthals & Vocal Learning

(00:09:29) Birdsong & Human Speech; Brain Circuit Parallels

(00:13:22) Hummingbirds; Vocal Learning Species & Complex Traits

(00:14:32) Critical Periods & Learning Your Native Song

(00:16:50) Pidgin Language & Cultural-Genetic Convergence

(00:18:36) Sponsor: AG1

(00:20:01) Genes Specialized in Speech Circuits

(00:23:05) Critical Period for Language Learning; Multilingualism

(00:25:17) Music, Emotion & Semantic vs. Affective Communication

(00:28:14) Sponsor: Eight Sleep

(00:29:49) Facial Expression & Speech Circuitry

(00:31:07) Written Language & Neural Pathways

(00:32:47) Stuttering; Basal Ganglia & Neurobiological Basis

(00:35:03) Texting & Language Evolution

(00:36:36) Tool: Movement, Dancing & Singing to Maintain Cognitive Health

(00:38:43) Recap

Disclaimer & Disclosures
Learn more about your ad choices. Visit megaphone.fm/adchoices