People, Parasites, and Plagues

The hosts sit down with Dr. Julie Fox, Chief of the Emerging Virus Immunity Unit at NIAID, National Institutes of Health, to explore the science of alphavirus immunity and what antibodies really do in the context of alphavirus infection.
From chikungunya virus and its debilitating joint disease to broader mosquito-borne alphaviruses, Dr. Fox explains why these viruses are powerful models for studying immune protection. We move beyond the traditional view of antibodies as simple neutralizers and examine Fc-mediated effector functions, viral escape, and how mechanistic immunology informs the design of more durable vaccines and antibody therapies.
Dr. Fox also shares her path into government research, what it takes to launch a lab at NIH, and the training programs available for graduate students and aspiring biologists interested in infectious disease research.

Parasitoid wasps are some of the most successful organisms on Earth, even if most of us never notice them.
In this episode, Dr. Michael Strand from the UGA Department of Entomology takes us inside the hidden world of parasitoid wasps. These insects lay their eggs in other insects and rely on domesticated viruses to suppress host immune systems and control development. We explore how these virus–wasp partnerships evolved over millions of years, why they have made parasitoid wasps incredibly diverse, and how their biology influences ecosystems and agricultural pest control.
From evolutionary arms races to real-world applications, this episode reveals a biological battle happening all around us, right under our noses.

What if your gut bacteria could become medicine?

In this episode, a UGA microbiologist, Greg Phillips, reveals how engineered probiotic E. coli can produce L-dopa, the frontline treatment for Parkinson’s, directly inside the gut. We explore the gut–brain connection, the power of the microbiome, and how living microbes could become the next generation of drug delivery systems.
From World War I probiotic strains to modern genetic engineering, this episode takes you inside a bold new frontier of microbiome-based medicine.

Dive into the world of chromatin and epigenetics with Dr. Zachary Lewis, an associate professor at the UGA Department of Microbiology. His research explores how chromatin structure and other epigenetic mechanisms shape genome organization, function, and long-term stability in eukaryotic cells. He particularly studies chromatin within fungal pathogens. In this episode, Dr. Lewis breaks down why these molecular systems matter, how they influence fungal disease, and the cutting-edge methods his lab uses to study them.

This episode takes us inside the lab of Dr. Drew Etheridge, an associate professor in the UGA Department of Cellular Biology. He walks us through his scientific path and his current work on endocytosis in Trypanosoma cruzi. This parasite is often overlooked, yet it is becoming increasingly prevalent in the United States as it moves north from Central and South America.