I speak with Johnathan Jarecki, undergraduate science student and host of The Signal Podcast, on all things photobiology. We discuss the full solar spectrum and how ultraviolet, visible, blue, red and near-infrared light each affect human physiology, including the POMC pathway, nitric oxide and blood pressure, and the evidence on sunlight, skin cancer and the vitamin D paradox.
We also discuss how artificial light at night suppresses melatonin and disrupts the circadian control of DNA repair, cardiovascular health, and metabolism.
TIMESTAMPS
03:25 Dr. Max Gulhane
04:02 Dr. Gulhane's Love for Science and Medicine
09:01 What is Light?
12:52 Sunlight Broken Down as a Nutrient
14:02 Ultraviolet Light: Sunlight Is More Than Vitamin D
15:56 POMC
21:38 UVA/UVB on Cardiometabolic Health
24:40 Big Picture of UV Light
28:41 Sunlight, Skin Cancer, Dermatology Messaging, The Vitamin D Paradox
35:10 Blue Light, Artificial Light at Night (ALAN), Mechanisms
38:50 Sponsor: Daylight Computer
40:34 ALAN, Epidemiology, Cancer, Heart Disease
45:04 DNA Repair Mechanisms, Circadian Control
47:27 Melanopsin (OPN4), Blue Light, UV Susceptibility
53:25 Red, Infrared, Photobiomodulation, Metabolism
01:00:08 Blue Light, Metabolism, and the Built Environment
01:05:19 Photobiology of Atherosclerosis
01:10:11 Blue Light on Cardiovascular Function
01:12:25 Three M's of Circadian Health
01:18:43 Sunlight, Testosterone, and Reproductive Behavior
Full show notes: https://docs.google.com/document/d/15zOnh_l6WOe6237CbQrFPkeoQjUZXIm9Ul4ncQTNXDQ/edit?pli=1&tab=t.0
Show sponsors:
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DISCLAIMER: The content in this podcast is purely for informational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay in seeking it because of something you have heard on this podcast or YouTube channel. Do not make medication changes without first consulting your treating clinician.
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