The Dr Vonda Show

📩 Get Dr. Vonda's insights
Want to understand what's happening in your body — and what to do next?
Each week, Dr. Vonda shares science-backed guidance on strength, bone health, muscle, and longevity — the same way she speaks to her patients.
Clear. Practical. No noise.
👉 Join the newsletter: https://manage.kmail-lists.com/subscriptions/subscribe?a=YqJKtR&g=Ww3gx3&
 
Today I sat down with Cindy Eckert, founder and CEO of Sprout Pharmaceuticals and the woman behind Addyi, the first and only FDA-approved medication for low sexual desire in women, often called the "female Viagra." This conversation is about so much more than a pill: it's about biology, agency, and why a switch going out in your brain deserves a medical answer, not a euphemism.
 
What we explore:
- Why desire begins in the brain, not the body.
- How Addyi works on dopamine and serotonin to restore interest.
- What women say when they describe losing their libido.
- Why HSDD can affect women from their teens through their eighties.
- How the double standard in men's versus women's sexual health stalled the science for decades.
- What words to use with your doctor to be taken seriously.
- Why medical gaslighting shows up the same way in sexual health as it does in orthopedics.
- How "The Pink Pill" documentary exposes gender bias in healthcare.
- Why it's okay to fire a clinician who blows you off.
 
About Cindy Eckert:
Cindy Eckert is the founder and CEO of Sprout Pharmaceuticals, maker of Addyi, the first FDA-approved treatment for low sexual desire in women. A serial entrepreneur with over $1.5 billion in company exits, she was named to the TIME100 Health 2026 list, Glossy's inaugural Wellness Founder of the Year, and Sprout was named one of TIME's 10 Most Influential Health and Life Science Companies of 2026. Addyi was also featured in Oprah's Menopause Awards. She's now the subject of the documentary "The Pink Pill," streaming on Paramount+.
 
Read more:
TIME100 Health 2026:https://time.com/article/2026/04/27/time100-companies-health/
NYT Profile: https://www.nytimes.com/2025/11/16/style/cindy-eckert-pink-pill-addyi.html
Oprah's Menopause Awards: https://www.oprahdaily.com/life/health/a69978304/oprah-menopause-awards-2026/
 
Connect with Cindy Eckert:
Website: addyi.com 
Instagram: https://www.instagram.com/cindypinkceo/ 
 
Grab an Addyi coupon for your telemed appointment
Use promo code VONDA to get $10 off
👉 addyi.com 
 
Timestamps
00:00 Intro
01:42 Medical Gaslighting in Women's Health
03:40 Female Desire and the Brain
05:35 How Women Describe Low Libido
08:24 The Science of Dopamine and Serotonin
10:34 How Addyi's Effects Build Over Time
12:55 Desire and a Sense of Wholeness
16:17 HSDD Across the Lifespan
19:08 The FDA's Resistance to Addyi
22:26 The Double Standard in Sexual Health
25:08 What to Say to Your Doctor
28:14 When to Fire Your Clinician
33:00 Treating Sexual Health as Medicine
36:22 Making of "The Pink Pill" Documentary
41:00 Women's Health Conversations 2026

🎤 Women's Health Conversations 2026
Three days of world-class speakers, wellness activations, and 1,000+ women choosing themselves. Join us this November.
👉 Grab your spot: https://theunbreakablelifestyle.com/whc-2026
 
🧠 Start your Unbreakable journey
Most women are never given a clear plan for how to stay strong as they age.
The Unbreakable Lifestyle is where that changes.
This is the home of Dr. Vonda's method — built from 20+ years of clinical work and designed for real life.
Inside:
 
Unbreakable Assessment — know exactly where you stand
Training plans — build muscle, protect bone, improve performance
AI Dr. Vonda — get answers and guidance anytime
Community — women committed to staying strong and engaged
Exclusive education — what actually works, all in one place
This is not another program.
This is how you build strength — with direction.
👉 Join the Unbreakable Lifestyle: https://www.theunbreakablelifestyle.com/
 
🦴 Build stronger bones
Bone loss starts earlier than you think — and speeds up in midlife.
Dr. Vonda's Unbreakable Bone Health formula supports bone density, strength, and long-term skeletal health with clinically researched ingredients.
Foundational. Not optional.
👉  Shop now: https://shop.drvondawright.com/
 
Read the book
Unbreakable: A Woman's Guide to Aging with Power
A clear, science-backed roadmap to building strength, supporting your body, and taking control of how you age.
Get your copy: https://www.theunbreakablelifestyle.com/unbreakable-book 
 
🧬 About Dr. Vonda Wright
Dr. Vonda Wright is an orthopedic sports surgeon and leading expert in women's health and longevity.
For over 20 years, she has helped women build muscle, strengthen bone, and extend their health span — with science, not guesswork.
Her mission is simple: help women age with power.
🔗 Connect with Dr. Vonda
Instagram: https://www.instagram.com/drvondawright/
Substack: https://drvondawright.substack.com/
TikTok: https://www.tiktok.com/@drvondawright
LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374
Website: http://www.drvondawright.com/

📩 Get Dr. Vonda's insights
Want to understand what's happening in your body — and what to do next?
Each week, Dr. Vonda shares science-backed guidance on strength, bone health, muscle, and longevity — the same way she speaks to her patients.
Clear. Practical. No noise.
👉 Join the newsletter: https://manage.kmail-lists.com/subscriptions/subscribe?a=YqJKtR&g=Ww3gx3&

Most people know they should exercise. The data is irrefutable. But knowing and doing are two very different things.
In this video I'm introducing a concept called Sedentary Death Syndrome 33 chronic diseases that will take hold if we don't intervene with daily movement. And the shocking truth is there is only one "drug" that treats all 33 of them. It's not in a pharmacy.
I'm also giving you the exact exercise prescription I use for women in midlife and beyond. I call it the FACE Framework — and it covers everything your body actually needs to stay strong, mobile, and powerful as you age. Not just cardio. Not just weights. All of it, in the right dose, in the right order.
If you've been wondering exactly what to do and how to do it, this is your answer.


🎤 Women's Health Conversations 2026
 Three days of world-class speakers, wellness activations, and 1,000+ women choosing themselves. Join us this November.
👉 Grab your spot: https://theunbreakablelifestyle.com/whc-2026

...
🧠 Start your Unbreakable journey
Most women are never given a clear plan for how to stay strong as they age.
The Unbreakable Lifestyle is where that changes.
This is the home of Dr. Vonda's method — built from 20+ years of clinical work and designed for real life.
Inside:
Unbreakable Assessment — know exactly where you stand
Training plans — build muscle, protect bone, improve performance
AI Dr. Vonda — get answers and guidance anytime
Community — women committed to staying strong and engaged
Exclusive education — what actually works, all in one place
This is not another program.
This is how you build strength — with direction.
👉 Join the Unbreakable Lifestyle: https://www.theunbreakablelifestyle.com/
🦴 Build stronger bones
Bone loss starts earlier than you think — and speeds up in midlife.
Dr. Vonda's Unbreakable Bone Health formula supports bone density, strength, and long-term skeletal health with clinically researched ingredients.
Foundational. Not optional.
👉  Shop now: https://shop.drvondawright.com/

...
📖 Read the book
Unbreakable: A Woman's Guide to Aging with Power
A clear, science-backed roadmap to building strength, supporting your body, and taking control of how you age.
👉  Get your copy: https://www.theunbreakablelifestyle.com/unbreakable-book

...
🧬 About Dr. Vonda Wright
Dr. Vonda Wright is an orthopedic sports surgeon and leading expert in women's health and longevity.
For over 20 years, she has helped women build muscle, strengthen bone, and extend their health span — with science, not guesswork.
Her mission is simple: help women age with power.
🔗 Connect with Dr. Vonda
Instagram: https://www.instagram.com/drvondawright
Substack: https://drvondawright.substack.com/
TikTok: https://www.tiktok.com/@drvondawright
LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374
Website: http://www.drvondawright.com

📩 Get Dr. Vonda's insights
Want to understand what's happening in your body — and what to do next?
Each week, Dr. Vonda shares science-backed guidance on strength, bone health, muscle, and longevity — the same way she speaks to her patients.
Clear. Practical. No noise.
👉 Join the newsletter: https://manage.kmail-lists.com/subscriptions/subscribe?a=YqJKtR&g=Ww3gx3&
 
I sat down with Dr. Iñigo San Millán, one of the world's leading researchers in cellular metabolism and mitochondrial function and the scientist whose methods I use every day in my practice, to decode the real science of Zone 2, lactate, and why your mitochondria are the engine of your entire health span.
 
What we explore:
- Lactate threshold testing measures mitochondrial function, metabolic health and flexibility
- Zone 2 and sprint intervals optimize VO2 max, glycolytic capacity, and healthy aging.
- Elevated resting lactate signals mitochondrial dysfunction and insulin resistance
- The astrocyte-neuron lactate shuttle links brain metabolism, cognitive decline, and Alzheimer's disease.
- Skeletal muscle governs glucose metabolism, insulin sensitivity, and the origin of insulin resistance.
- Mitochondrial decline and bioenergetic dysfunction silently precede type 2 diabetes in sedentary individuals.
- Metabolic dysfunction and insulin resistance are reversible at any age through Zone 2 training and structured exercise.
 
About Dr. Iñigo San Millán:
Dr. Iñigo San Millán is an exercise physiologist and researcher at the University of Colorado School of Medicine whose work on mitochondrial function and cellular metabolism has shaped how both elite athletes and everyday people train for health and longevity. He is best known for pioneering the science of Zone 2 training and coaching Tour de France champion Tadej Pogačar.
 
Connect with Dr. Iñigo San Millán:
Instagram: https://www.instagram.com/inigosanmillan/
 
Timestamps
 
00:00 Intro 
03:58 Lactate Testing: Your Mitochondrial Stress Test 
05:38 Why Lactate Is Fuel, Not the Enemy 
12:07 Zone 2 Training: What the Science Actually Shows 
15:39 Why Elite Athletes Train Slow to Perform Fast 
19:40 Zone 2 Gets Harder as Your Fitness Improves 
24:29 Why Sprint Intervals Are Non-Negotiable 
31:10 Your Brain Prefers Lactate Over Glucose 
33:00 The CGM for Lactate: How Close Are We? 
36:54 Why Skeletal Muscle Is Your Longevity Organ 
40:53 Estrogen, Brain Energy, and Alzheimer's Risk 
46:10 Are Children Missing a Critical Metabolic Window? 
50:11 The Inside-Out Hypothesis: Hidden Metabolic Decline 
52:48 It's Never Too Late to Reverse Metabolic Disease
 
🧴 OneSkin
Target visible aging at the source with OneSkin's clinically proven OS-01 Peptide.
👉 Get 15% off with code DRVONDA at https://oneskin.co/DRVONDA

🎤 Women's Health Conversations 2026
Three days of world-class speakers, wellness activations, and 1,000+ women choosing themselves. Join us this November.
👉 Grab your spot: https://theunbreakablelifestyle.com/whc-2026
 
🧠 Start your Unbreakable journey
Most women are never given a clear plan for how to stay strong as they age.
The Unbreakable Lifestyle is where that changes.
This is the home of Dr. Vonda's method — built from 20+ years of clinical work and designed for real life.
Inside:
 
Unbreakable Assessment — know exactly where you stand
Training plans — build muscle, protect bone, improve performance
AI Dr. Vonda — get answers and guidance anytime
Community — women committed to staying strong and engaged
Exclusive education — what actually works, all in one place
This is not another program.
This is how you build strength — with direction.
👉 Join the Unbreakable Lifestyle: https://www.theunbreakablelifestyle.com/
 
🦴 Build stronger bones
Bone loss starts earlier than you think — and speeds up in midlife.
Dr. Vonda's Unbreakable Bone Health formula supports bone density, strength, and long-term skeletal health with clinically researched ingredients.
Foundational. Not optional.
👉  Shop now: https://shop.drvondawright.com/
 
Read the book
Unbreakable: A Woman's Guide to Aging with Power
A clear, science-backed roadmap to building strength, supporting your body, and taking control of how you age.
Get your copy: https://www.theunbreakablelifestyle.com/unbreakable-book 
 
🧬 About Dr. Vonda Wright
Dr. Vonda Wright is an orthopedic sports surgeon and leading expert in women's health and longevity.
For over 20 years, she has helped women build muscle, strengthen bone, and extend their health span — with science, not guesswork.
Her mission is simple: help women age with power.
🔗 Connect with Dr. Vonda
Instagram: https://www.instagram.com/drvondawright/
Substack: https://drvondawright.substack.com/
TikTok: https://www.tiktok.com/@drvondawright
LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374
Website: http://www.drvondawright.com/

📩 Get Dr. Vonda's insights Want to understand what's happening in your body — and what to do next? Each week, Dr. Vonda shares science-backed guidance on strength, bone health, muscle, and longevity — the same way she speaks to her patients. Clear. Practical. No noise.
👉 Join the newsletter: https://manage.kmail-lists.com/subscriptions/subscribe?a=YqJKtR&g=Ww3gx3&

Your shoulder hurts and you did nothing to injure it. Your knees ache. Your back is acting up. Everything feels inflamed and nobody is giving you a straight answer. You are not falling apart. You are not going crazy. There is a name for what is happening to you.
It is called the Musculoskeletal Syndrome of Menopause — and it is one of the most under-discussed, under-diagnosed conditions affecting women in midlife today. When estrogen walks out the door, it doesn't just affect your reproductive system. Every single part of your skeletal system — your muscles, your bones, your joints, your tendons, your cartilage, your spinal discs — has estrogen receptors. And when those receptors go unfilled, the cascade that follows is real, it is measurable, and it is happening to you right now whether you feel it or not. In this video I am breaking down exactly what is happening inside your body during this transition and what you can do to get in front of it before it becomes a crisis. 
 
🎤 Women's Health Conversations 2026 Three days of world-class speakers, wellness activations, and 1,000+ women choosing themselves. Join us this November. 👉 Grab your spot: https://theunbreakablelifestyle.com/whc-2026

🧠 Start your Unbreakable journey Most women are never given a clear plan for how to stay strong as they age. The Unbreakable Lifestyle is where that changes. This is the home of Dr. Vonda's method — built from 20+ years of clinical work and designed for real life. Inside:

Unbreakable Assessment — know exactly where you stand Training plans — build muscle, protect bone, improve performance AI Dr. Vonda — get answers and guidance anytime Community — women committed to staying strong and engaged Exclusive education — what actually works, all in one place This is not another program.
This is how you build strength — with direction. 👉 Join the Unbreakable Lifestyle: https://www.theunbreakablelifestyle.com/

🦴 Build stronger bones Bone loss starts earlier than you think — and speeds up in midlife. Dr. Vonda's Unbreakable Bone Health formula supports bone density, strength, and long-term skeletal health with clinically researched ingredients. Foundational. Not optional. 👉 Shop now: https://shop.drvondawright.com/

...
 
📖 Read the book Unbreakable: A Woman's Guide to Aging with Power A clear, science-backed roadmap to building strength, supporting your body, and taking control of how you age. 👉 Get your copy: https://www.theunbreakablelifestyle.com/unbreakable-book ...

🧬 About Dr. Vonda Wright Dr. Vonda Wright is an orthopedic sports surgeon and leading expert in women's health and longevity. For over 20 years, she has helped women build muscle, strengthen bone, and extend their health span — with science, not guesswork. Her mission is simple: help women age with power.

🔗 Connect with Dr. Vonda Instagram: https://www.instagram.com/drvondawright Substack: https://drvondawright.substack.com/ TikTok: https://www.tiktok.com/@drvondawright LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374 Website: http://www.drvondawright.com

Get Dr. Vonda's insights
Want to understand what's happening in your body — and what to do next?
Each week, Dr. Vonda shares science-backed guidance on strength, bone health, muscle, and longevity — the same way she speaks to her patients.
Clear. Practical. No noise.
Join the newsletter: https://manage.kmail-lists.com/subscriptions/subscribe?a=YqJKtR&g=Ww3gx3&
 
I sit down with Dr. Doris Day, board-certified dermatologist and clinical associate professor at NYU, to explore what perimenopause and menopause are really doing to your skin and what you can do about it from the inside out.
 
What We Explore:
 
- Why skin is the first organ to feel estrogen loss, sometimes years before other symptoms appear.
- How collagen collapse accelerates around menopause, with up to 30% lost in the first five years.
- Why facial bone resorption changes your orbital structure and jawline as you age.
- How simple facial posture exercises can preserve muscle tone without surgery.
- Why sugar and alcohol accelerate skin aging and how diet supports skin from the inside out.
- What hydrolyzed collagen supplements actually do in the body.
- How hormone therapy, retinoids, and topicals work together as a nighttime protocol.
- Why deep sleep and REM are among the most underrated factors in how your skin heals.
 
About Dr. Doris Day:
Dr. Doris Day, MD, is a board-certified dermatologist specializing in cosmetic and longevity dermatology. She is a Clinical Professor of Dermatology at NYU Langone Health, where she has been recognized with the Award for Dedication and Excellence in the Teaching of Dermatology. Her leadership in aesthetic dermatology has earned her the AAD Presidential Citation and the American Skin Association Award for leadership in dermatology.
 
Connect with Dr. Doris Day:
Website: https://dorisdaymd.com/
Instagram: https://www.instagram.com/drdorisday/
LinkedIn: https://www.linkedin.com/in/drdorisday
YouTube: https://www.youtube.com/c/DorisDayMDCosmeticDermatology

Timestamps
 
Intro (00:00)
Why Skin Is Your Most Important Organ (01:46)
Skin Loses Estrogen Before Your Brain Does (05:21)
How to Stop 30% Collagen Loss After Menopause (07:10)
Why Your Face Sinks: The Bone Changes Explained (09:34)
Stop Chasing Your 20s Face (11:25)
The Ear-Lift Trick That Replaces Forehead Botox (17:00)
What Hyaluronic Acid Actually Does (And What It Can't) (22:24)
Why One Treatment Will Never Be Enough (26:01)
Sugar Is Poison for Your Skin, Here's the Fix (28:33)
The mTOR Switch Making Your Skin Age Faster (36:23)
The 3 Ingredients Every Woman Over 45 Needs (44:07)
The Sleep Metric That's Aging Your Face (47:35)
What Women Who Age Powerfully All Have in Common (49:38)
 
🧴 OneSkin
Target visible aging at the source with OneSkin's clinically proven OS-01 Peptide.
👉 Get 15% off with code DRVONDA at https://oneskin.co/DRVONDA

🎤 Women's Health Conversations 2026
Three days of world-class speakers, wellness activations, and 1,000+ women choosing themselves. Join us this November.
👉 Grab your spot: https://theunbreakablelifestyle.com/whc-2026

Start your Unbreakable journey
Most women are never given a clear plan for how to stay strong as they age.
The Unbreakable Lifestyle is where that changes.
This is the home of Dr. Vonda's method — built from 20+ years of clinical work and designed for real life.
Inside:
- Unbreakable Assessment — know exactly where you stand
- Training plans — build muscle, protect bone, improve performance
- AI Dr. Vonda — get answers and guidance anytime
- Community — women committed to staying strong and engaged
- Exclusive education — what actually works, all in one place
This is not another program.
This is how you build strength — with direction.
Join the Unbreakable Lifestyle: https://www.theunbreakablelifestyle.com/

Build stronger bones
Bone loss starts earlier than you think — and speeds up in midlife.
Dr. Vonda's Unbreakable Bone Health formula supports bone density, strength, and long-term skeletal health with clinically researched ingredients.
Foundational. Not optional.
Shop now: https://shop.drvondawright.com/
 
Read the book
Unbreakable: A Woman's Guide to Aging with Power
A clear, science-backed roadmap to building strength, supporting your body, and taking control of how you age.
Get your copy: https://www.theunbreakablelifestyle.com/unbreakable-book 
 
About Dr. Vonda Wright
Dr. Vonda Wright is an orthopedic sports surgeon and leading expert in women's health and longevity.
For over 20 years, she has helped women build muscle, strengthen bone, and extend their health span — with science, not guesswork.
Her mission is simple: help women age with power.
 
Connect with Dr. Vonda
Instagram: https://www.instagram.com/drvondawright
Substack: https://drvondawright.substack.com/
TikTok: https://www.tiktok.com/@drvondawright
LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374
Website: http://www.drvondawright.com