American Journal of Psychiatry Audio
American Journal of Psychiatry

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224 episodes
81: Psychiatric Risk Associated With Large Language Model Chatbots: An Emerging Concern
15/08/2026 | 26 mins.Amandeep Jutla, M.D., joins Dr. Dixon and Dr. Berezin, with guest host Dr. Matt Hirschtritt, to discuss concerns surrounding the use of large language model chatbots and psychiatric risk.
01:08Â Â Introduction
04:03Â Â Language models in 2019
05:18Â Â The appeal of chat-based AI for autistic adults
07:34Â Â Do you use chat-based AI models personally?
09:44Â Â Specific concerns of interacting with AI chat bots
11:07Â Â The illusion of speaking with a person
13:34Â Â Suggestions for clinicians and researchers
16:17Â Â Questions a clinician should ask
18:29Â Â Uses for AI models
20:11Â Â Can chat bots get good at providing advice?
21:30Â Â Regulations?
24:12Â Â Motivational interviewing
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Transcript
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E-mail us at psjournal@psych.orgAugust 2026: Cognitive, Electrophysiological, and Behavioral Presentation of First-Episode Psychosis With or Without Cannabis Exposure
01/08/2026 | 33 mins.Dr. Deepak Cyril D'Souza (Yale University School of Medicine) joins the podcast to discuss a study looking at two cohorts of patients hospitalized with first instances of psychosis, one with cannabis exposure and one without. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin takes us through the August issue of the Journal, which takes a look at issues surrounding schizophrenia spectrum disorder, from the clinical to basic science.
00:40 Â Â Â D'Souza interview
02:38Â Â Â Â Subtyping and schizophrenia spectrum disorder
04:19Â Â Â Â Relapse and long-term implications for cannabis induced psychosis
05:43Â Â Â Â Improvements in cognition
08:03Â Â Â Â Differences between the groups
09:26Â Â Â Â Greater access and greater potency of cannabis products
11:29Â Â Â Â Further research
13:45Â Â Â Â Kalin interview
13:59Â Â Â Â D'Souza et al.
21:34Â Â Â Â Forsyth et al.
27:36Â Â Â Â Enwright et al.
Transcript
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E-mail us at ajp@psych.orgJuly 2026: Social Determinants of Health in Psychiatric Disorders: Exciting Opportunities for Biopsychosocial Research and Clinical Care
01/07/2026 | 37 mins.Dr. Dilip Jeste (Social Determinants of Health Network, La Jolla, CA) joins the podcast to discuss how social determinants of health interact with treatment for psychiatric disorders. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin once again puts the rest of the July issue into context.
00:31Â Â Â Â Impacts of social determinants of health on psychiatric disorders, research, and clinical care
04:43Â Â Â Â Health related social needs versus social determinants of health
08:47Â Â Â Â Loneliness as a risk factor
12:36Â Â Â Â A clinician's role in societal factors
14:47Â Â Â Â Mechanistic understandings social determinants and the exposome
18:17Â Â Â Â Further research
22:25Â Â Â Â Kalin interview
22:30Â Â Â Â Jeste and Gyan
23:33Â Â Â Â Blundell et al.
28:03Â Â Â Â Yang et al.
32:20Â Â Â Â Van der Meer et al.
Transcript
Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it.
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E-mail us at ajp@psych.orgJune 2026: Low-Dose Buprenorphine Following Ketamine Treatment for Suicidal Ideation in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial
01/06/2026 | 29 mins.Dr. Jason Tucciarone and Dr. Alan Schatzberg (Stanford University, Stanford, CA) join AJP Audio to discuss the use of low-dose buprenorphine as an adjunctive therapy to extend the anti-suicidal effects of ketamine treatment in patients with major depressive disorder and suicidal ideation. AJP Editor-in-Chief Dr. Ned Kalin joins to discuss the rest of the June issue of the Journal, which takes a close look at issues surrounding suicide and severe depression.
01:20Â Â Â Â Tucciarone and Schatzberg interview
03:36Â Â Â Â Disparity between effects on suicidal ideation and antidepressant ratings
05:36Â Â Â Â Ethics of placebo and ketamine in patients with suicidal ideation
08:28Â Â Â Â Immediate clinical implications
11:40Â Â Â Â Limitations
14:10Â Â Â Â Further research
16:19Â Â Â Â Kalin interview
16:24Â Â Â Â Tucciarone et al.
20:39Â Â Â Â Rovers et al.
24:30Â Â Â Â Jelen et al.
Transcript
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E-mail us at ajp@psych.org- In this special episode of AJP Audio, AJP Editor-in-Chief Dr. Ned Kalin is joined by Dr. MarÃa Oquendo (Perelman School of Medicine at the University of Pennsylvania, Philadelphia), chair of APA's Future DSM Strategic Committee to discuss a series of commentaries published in the May issue of the Journal discussing the strategic vision for the future of DSM.
00:39Â Â Oquendo interview
03:07Â Â Size of the response
04:18Â Â Feedback
06:04Â Â Incorporating the feedback
07:57Â Â Emphasizing science with a title change for DSM
10:18Â Â A living document
12:35Â Â Changes from previous versions of DSM
16:08Â Â Changes in documentation and coding
18:51Â Â Lived experience
20:02Â Â Working with AJP
Links to the commentaries:Â
Initial Strategy for the Future of DSM
MarÃa A. Oquendo, M.D., Ph.D., et al.
The Future of DSM: A Report From the Structure and Dimensions Subcommittee
Dost Öngür, M.D., Ph.D., et al.
The Future of DSM: Are Functioning and Quality of Life Essential Elements of a Complete Psychiatric Diagnosis?
Karen Drexler, M.D., et al.
The Future of DSM: Role of Candidate Biomarkers and Biological Factors
Bruce Cuthbert, Ph.D., et al.
The Future of DSM: A Strategic Vision for Incorporating Socioeconomic, Cultural, and Environmental Determinants and Intersectionality
Milton L. Wainberg, M.D., et al.
Transcript
Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it.
Subscribe to the podcast here.
Listen to other podcasts produced by the American Psychiatric Association.
Browse articles online.
How authors may submit their work.
Follow the journals of APA Publishing on Twitter.
E-mail us at ajp@psych.org
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About American Journal of Psychiatry Audio
Each episode of AJP Audio brings you an in-depth look at one of the articles featured in that month's issue of The American Journal of Psychiatry, the official journal of the American Psychiatric Association. Wide-ranging interviews with article authors cover the background, rationale, main findings, and future implications of the research.
This podcast is subject to the Terms of Use at ww.psychiatry.org. The views and opinions expressed in this podcast are those of the individual speakers only and do not necessarily represent the views of the American Psychiatric Association, its officers, trustees, or members. The content of this podcast is provided for general informational purposes only and is not intended as, and shall not be understood or construed as, medical or any other type of professional advice nor does it represent any statement of the standard of care. We strongly recommend that any listener follow the advice of physicians directly involved in their care and contact their local emergency response number for any medical emergency. The information within this podcast is provided as-is and is not guaranteed to be correct, complete, or accurate.
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