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Clinical Changemakers

Inspiring Clinicians to Thrive
Clinical Changemakers
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  • From Evidence to Exit: Building Credible Health Tech | Dr Saira Ghafur (Co-Founder of Provea Health & Lead for Digital Health at Imperial College)
    “The market was flooded with all these new tools and technologies that people were using, but no real evidence base behind them. Now we’re in this space where we need evidence. — Dr Saira GhafurListen now on Apple, Spotify, YouTube or wherever you get your podcasts.Dr Saira Ghafur is a medical doctor specialising in respiratory medicine, an academic and expert in digital health at Imperial College London, and co-founder of two startups, including Prova Health, where she serves as Chief Medical Officer. Her work spans cybersecurity in healthcare, evidence generation for digital health technologies, and translating research into practical applications that improve healthcare systems.What you'll learn:* Why healthcare cybersecurity attacks have grown fivefold and become increasingly sophisticated and state-sponsored* The unique challenges of healthcare cybersecurity compared to other critical sectors like finance or energy* How to build resilient health systems that can continue providing care during cyberattacks* Why digital health technologies remain a "wild west" when it comes to evidence generation* The importance of gathering different types of evidence throughout a product's lifecycle—from qualitative user research to clinical outcomes and economic evidence* How simulation and synthetic patient data can help evaluate digital health tools in low-risk environments* The challenges of creating evidence for AI in healthcare and why data quality is fundamental* Lessons learned from founding two healthcare startups as a clinicianKey TakeawaysCybersecurity is healthcare's blind spot: Despite healthcare's increasing digitisation, research into cybersecurity resilience lags far behind other critical sectors, creating significant vulnerabilities.Resilience requires planning for multiple catastrophes: Healthcare organisations must prepare not just for cyber attacks but for compounding disasters, like a cyber attack followed by a mass casualty event.Evidence generation must match the product lifecycle: Early-stage technologies need qualitative user research, while mature products require real-world evidence gathering—one size doesn't fit all.Data accessibility is crucial but challenging: Access to high-quality healthcare data remains difficult, especially for smaller innovators who can't afford to clean and curate it properly.Secure data environments offer a path forward: Creating spaces where innovators can access data without it leaving the secure environment addresses both security concerns and patient fears.Economic evidence is increasingly essential: With constrained healthcare budgets, proving value for money has become non-negotiable for digital health technologies.Where to Find Dr Saira GhafurLinkedInIn This Episode00:00 - Introduction to cybersecurity in healthcare01:04 - How cyber threats have evolved in healthcare04:45 - Building resilient healthcare systems08:47 - The research landscape in healthcare cybersecurity11:17 - Digital health technologies and evidence generation15:48 - Regulatory challenges in digital health21:45 - Using simulation for evidence generation26:02 - Evidence generation for AI in healthcare31:44 - The importance of high-quality data34:32 - Economic evidence in digital health36:35 - Lessons learned as a clinician founderReferenced:* Challenges for the evaluation of digital health solutions - A call for innovative evidence generation approaches (Paper)* Safeguarding our healthcare systems: A global framework for cybersecurity (Paper)* FDA - Software as a medical device (Website)* NICE - Evidence standards framework (ESF) for digital health technologies (Website)* PECAN - Fast Track Digital Tools in France (Website)* DiGA - Fast Track Digital Tools in Germany (Website)* Prova Health (Website)* Generating economic evidence for digital health solutions (White paper)* Trust through evidence: Evidence generation for AI solutions in healthcare (White paper)* Be Smarter than your lawyer and your VC (Book)Contact Information:If you have any feedback, questions or if you'd like to get in touch, reach out at [email protected] Attribution: Music by AudioCoffee from Pixabay👍Hi, Jono here - if you're enjoying my work, please share it with a friend or colleague. Thank you for your support This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.clinicalchangemakers.com
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  • Customer Obsession in Healthcare: Primary Care Redefined | Dr Raj Behal (Amazon One Medical)
    "I think of quality as what is the patient's ‘job to be done’. What are they trying to get out of this encounter or from their help? What are they trying to achieve? Making quality about that."— Dr Raj Behal.Listen now on Apple, Spotify, YouTube or wherever you get your podcasts.Dr. Raj Behal is a medical doctor and Chief Quality Officer at Amazon One Medical. With a background in internal medicine, medical informatics, and public health, Dr. Behal has spent his career translating evidence into better care. Before joining One Medical, he worked with academic medical centers to improve quality metrics and patient outcomes. Today, he's focused on redefining quality in primary care through a blend of in-person visits, 24/7 virtual care, and digital health solutions.What you'll learn:* The #1 mistake in healthcare quality—focusing on metrics rather than the patient's "job to be done"* Why quality in healthcare requires solving the "three-body problem" of patients, providers, and payers simultaneously* The power of simple, targeted follow-up questions like "Are you better?" to measure what truly matters* How AI and large language models could transform healthcare by passively extracting quality signals from unstructured data* The vital importance of the "reservoir"—addressing pre-disease conditions before they become chronic illnesses* An ambitious vision for knocking heart disease from its decades-long position as America's #1 killer* How healthcare quality should encompass multiple dimensions: safety, timeliness, effectiveness, efficiency, equity, and patient-centerednessKey Takeaways* Quality is multidimensional: The Institute of Medicine defines healthcare quality through six domains—safe, timely, effective, efficient, equitable, and patient-centered—but these shouldn't be viewed as separate boxes to check.* Standard metrics aren't enough: HEDIS measures like cancer screening rates and diabetes control are important but capture only "a sliver of what people actually want from their health and healthcare providers."* Respect drives efficiency: One Medical starts appointments exactly on time not because of efficiency targets but out of genuine respect for patients' time—a cultural shift that transforms the care experience.* The coaching approach works: When hospitals received mortality data without guidance, nothing changed. When Dr. Behal worked directly with clinical teams to interpret the data and develop solutions, mortality rates dropped 20-25% in less than a year.* Technology should augment, not replace: The future isn't about AI diagnosing patients but about automating routine tasks—"about 80% of routine testing screenings can be ordered by a machine," freeing clinicians for higher-value work.Where to Find Dr BehalLinkedInIn This Episode00:00 - Introduction to quality in healthcare 02:57 - Defining comprehensive healthcare quality 07:19 - Approaches to meaningful healthcare measurement 14:00 - Using AI to extract quality signals from clinical data 19:51 - Importance of coaching in quality improvement 28:45 - The One Medical model and Amazon acquisition 33:31 - The "three-body problem" in healthcare delivery 40:47 - Ambitious goals for transforming heart disease preventionReferenced:* Six Domains of Healthcare Quality (Website)* The Healthcare Effectiveness Data and Information Set (HEDIS) (Website)* Failure mode and effects analysis (FMEA) (Website)* Amazon’s PR/FAQ process (Website)Contact information:If you have any feedback, questions or if you'd like to get in touch, reach out at [email protected] Attribution: Music by AudioCoffee from Pixabay👋Hi, Jono here - if you’re enjoying my work, please share it with a friend! Thanks for your support! This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.clinicalchangemakers.com
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  • The Economic Imperative: Why Health Equity Matters for Everyone | Prof. Bola Owolabi (NHS England Director)
    "The greatest legacy we can leave as this generation of leaders is to make meaningful progress in narrowing those health inequalities between communities."— Prof Bola Owolabi.Episode OverviewIn this episode, Professor Bola Owolabi, GP and National Director for Healthcare Inequalities at NHS England, shares her insights on health inequalities in England, how the COVID-19 pandemic exposed pre-existing disparities, her views on leadership and the innovative Core20Plus5 framework she's implementing to drive meaningful change across communities.What you'll learn:* How the COVID-19 pandemic exposed pre-existing health inequalities and acted as a catalyst for systemic change.* Why addressing health inequalities has both moral and economic imperatives, potentially saving healthcare systems billions annually.* The framework behind Core20Plus5 and how it provides focus, traction, and impact by targeting specific populations and clinical areas.* Why community engagement and listening are fundamental to designing effective healthcare interventions.* How a comprehensive ecosystem approach with multiple levers—including legislation, research, innovation, and funding—drives sustainable change.* The distinction between courage as an individual trait versus a function of supportive community and shared values.Some Key Takeaways* Health inequalities cost the NHS approximately £5 billion annually, with additional costs of £30 billion in productivity losses and another £30 billion in reduced tax revenue and higher welfare payments.* The COVID-19 pandemic didn't create health inequalities but exposed existing disparities: Black men experienced 2.2 times higher mortality in the second wave, while men from Bangladeshi backgrounds had 5 times higher mortality in the first wave.* Pre-pandemic data showed stark life expectancy gaps: 10-15 years for people with learning disabilities, 15-20 years for those with serious mental illness, and a 19.6-year difference in healthy life expectancy between the most and least affluent areas.* Core20Plus5 provides a clear framework for action by focusing on the 20% most socioeconomically deprived populations (Core20), plus specific underserved communities, across five clinical areas with significant mortality disparities.* Effective healthcare delivery requires meeting communities where they are—like mobile clinics for fishing communities whose livelihoods depend on unpredictable sea conditions.* Innovation for Health Inequalities Program (InHIP) leverages trusted community voices to increase uptake of approved treatments, resulting in a 70% rise in cholesterol-lowering medication use among Black African communities in Greater Manchester (UK).* Courageous leadership requires surrounding yourself with people who share your values but are willing to challenge you—creating psychological safety through "community and company rather than lonesome leadership."Where to find Professor Bola Owolabi* LinkedInIn This Episode* 00:01 - Introduction to Professor Bola Owolabi* 00:22 - Defining health inequalities and their impact* 01:36 - Distinction between inequality and inequity* 03:18 - How COVID-19 exposed pre-existing health inequalities* 08:44 - Community engagement experiences and listening to affected populations* 14:56 - Economic costs and business case for addressing health inequalities* 20:51 - How leadership enabled strategic focus on health inequalities* 25:18 - The importance of courage and support in leadership* 30:27 - Core20Plus5 framework explanation and implementation* 36:38 - Innovation for Health Inequalities Program examples* 44:16 - Scaling and sustaining change through a comprehensive ecosystem approachReferenced:* 8 Urgent actions to address inequalities in NHS provision and outcomes (Report)* Red Cross report on high use of emergency care utilization (Report)* Core20PLUS5 (Webpage)* Deloitte - US health care can’t afford health inequities (Report)* NIHR launches £50m ‘Challenge’ funding to tackle inequalities in maternity care (Webpage)* Health and Care Act of 2022 (Webpage)* Innovation for Healthcare Inequalities Programme (InHIP) (Webpage)Contact information:If you have any feedback, questions or if you'd like to get in touch, reach out at [email protected] Attribution: Music by AudioCoffee from Pixabay👋Hi, Jono here - if you’re enjoying my work, please share it with a friend, it would mean a lot to me!Thank you. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.clinicalchangemakers.com
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  • Money, Power, Health: How Corporations Shape Our Health | Dr. Nason Maani (Commercial Determinants Researcher)
    "The health impact of corporate power isn't just about products—it's about how commercial interests shape the entire landscape of health policy and research." — Dr Nason MaaniListen now on Apple, Spotify, YouTube or wherever you get your podcasts.Dr Nason Maani, lecturer in Inequalities and Global Health Policy at the University of Edinburgh, author of "The Commercial Determinants of Health," and host of the podcast “Money, Power, Health” discusses the complex interplay between commercial interests, power dynamics, and health outcomes.What You'll Learn:* How multinational corporations employ similar sophisticated strategies to influence health policy, including lobbying, revolving door employment, and strategic philanthropy* The specific ways commercial actors shape evidence through research funding priorities and selective publication of results* Why structural market failures in healthcare create environments where commercial interests can dominate public health concerns* How to identify and counteract corporate messaging that shifts responsibility for health from systems to individuals* The measurable impacts of commercial determinants on health inequities across different socioeconomic groups and geographic regionsSome Takeaways:* Understanding the commercial determinants of health is essential for addressing root causes of health issues* Corporate actors view their customer base very differently than we do, putting a high reliance on ‘super-users’* Public health approaches must consider the influence of commercial interests if they are to be successful* Transparency about financial interests in healthcare research and policy is crucial for building trustWhere to find Dr Nason Maani* LinkedInIn this episode, we cover:(00:00) Introduction to Dr. Nesimani(01:00) Overview of commercial determinants of health(05:30) The "Money, Power, Health" podcast journey(10:45) Key themes from "The Commercial Determinants of Health" book(15:20) Case studies of commercial influence on health policy(22:15) Strategies for clinicians to navigate commercial pressures(28:40) Global variations in commercial determinants(34:10) Future directions for research and advocacy(40:25) Practical tools for identifying commercial bias(49:19) Closing thoughts and resourcesReferenced:* Money, Power, Health (Podcast)* The Commercial Determinants of Health (Book)* The WHO - Commercial Determinants of health (Article)Contact information:If you have any feedback, questions or if you'd like to get in touch, reach out at [email protected] Attribution: Music by AudioCoffee from Pixabay This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.clinicalchangemakers.com
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  • Science Communication: Why the Basics Matter in an Age of Sound Bites | Dr Aaron Carroll (CEO of Academy Health)
    "I'd rather have people understand why they should believe something, not just that they should." — Dr Aaron CarrollListen now on Apple, Spotify, YouTube and or wherever you get your podcasts.Dr Aaron Carroll, pediatrician, professor, president and CEO of Academy Health, and renowned science communicator, discusses the art and science of effective communication in healthcare. Learn how he developed his skills through years of dedicated practice at the Incidental Economist, to global reach at the New York Times. He reflects on the challenges of translating complex research into accessible content, and why building trust is essential for changing minds.What You'll Learn:* Why repetition and consistency are fundamental to effective science communication* How to build trust through transparency, evidence-based reasoning, and admitting when you're wrong* Why the academic publishing model limits practical applications of research* The challenges of communicating during the COVID-19 pandemic and navigating controversial topics* How to balance personal storytelling with scientific rigor in public-facing contentSome Takeaways:* Science communication requires consistent practice and coaching, just like any other skill* Academic research often takes years or decades to translate into practice, often due to communication barriers* Many healthcare practices lack strong evidence, yet professionals often present all recommendations with equal confidence* Building trust requires explaining not just what to do, but why it matters and the evidence behind it* Personal stories can significantly increase audience engagement and build trust when balanced with scientific evidenceWhere to find Dr Aaron Carroll:* Twitter/X* LinkedInIn this episode, we cover:(00:00) Introduction to Dr. Aaron Carroll (01:00) Why science communication became his passion (02:30) The gap between academic and public communication(06:30) The limitations of peer-reviewed literature (08:33) How to develop science communication skills (13:16) Building trust through consistency and transparency (16:43) Institutional approaches to science communication (19:36) Addressing myths and biases in healthcare (23:40) Challenges with clinical decision support systems (28:33) Writing for the New York Times during COVID-19 (32:22) Navigating controversial healthcare topics (37:00) The power of personal storytelling in science writing (41:50) Balancing scientific rigor with accessibilityReferenced:* The Incidental Economist: https://theincidentaleconomist.com/wordpress/* Healthcare Triage: https://www.healthcaretriage.info/* Academy Health: https://academyhealth.org/* New York Times - Dr Carroll's articles: https://www.nytimes.com/by/aaron-e-carroll* About Aaron Carroll - https://academyhealth.org/about/people/aaron-e-carroll-md-ms* Dr Carroll’s BooksContact information: If you have any feedback, questions or if you'd like to get in touch, reach out at [email protected] Attribution: Music by AudioCoffee from Pixabay This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.clinicalchangemakers.com
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About Clinical Changemakers

Clinicians have trained in the art and science of medicine, and yet feel powerless to make a meaningful impact on the healthcare system. Clinical Changemakers is the podcast looking to bridge this gap by exploring inspiring stories of leadership, innovation and so much more. To learn more and join the conversation, visit: www.clinicalchangemakers.com www.clinicalchangemakers.com
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