Faces of Digital Health

In this episode, Dipak Kalra, President of the European Institute for Innovation through Health Data, joins Faces of Digital Health to break down the real progress (and real gaps) in European health data, from legacy “hybrid” paper/digital workflows to the underused potential of clinical decision support that depends on structured data. We explore what EHDS changes—especially the promise of a standardized, downloadable patient dataset—and what it could unlock for patient-facing apps, analytics, and more active self-management. We also tackle the hard questions: how to protect citizens from misuse and scams, how opt-out choices might create bias in research and AI, why “beating clinicians with a stick” won’t fix data quality, and why delays aren’t just bureaucratic—they can translate into avoidable harm. 02:00 The State of Healthcare Data in Europe 07:59 Challenges in Data Interoperability 12:31 The Role of Patients in Data Management 16:37 AI and Data Privacy Concerns 22:01 Patient Consent and Data Usage 28:00 Optimism for the Future of Health Data 31:03 Optimistic Futures for EAGDS 33:02 Preparing for EHDs: Readiness and Challenges 35:48 Data Quality and Workforce Challenges 37:58 Delays and Future Discussions on EHDs 39:53 The Urgency of Health Data Readiness 42:38 The Evolving Role of Patients in Healthcare 50:19 Building Trust Among Healthcare Stakeholders 57:58 The Future of Healthcare Data Discussions

Ali Parsa is a serial entrepreneur known for founding companies that challenge traditional models of healthcare delivery. Over two decades, he has built organizations at the intersection of healthcare, technology, and systems redesign—each shaped by an ambition to make care more efficient, accessible, and equitable. In this episode, Tjasa Zajc and Ali Parsa explore how agentic AI is redefining healthcare and what it really takes to build transformative companies in a fast-shifting world.Ali dives into why healthcare remains stuck in an economic imbalance—unlimited demand but constrained clinical supply—and why autonomous, real-time AI agents may finally rebalance the system by taking over 20–30% of routine clinical tasks. He explains how Quadrivia builds agents that can talk to patients, follow multi-step workflows, and operate within strict guardrails to avoid hallucinations and workflow drift.But this episode goes far beyond technology. Ali opens up about entrepreneurship:• why speed is the only real advantage startups have,• how to hire “missionaries, not mercenaries,”• why products must be excellent from day one,• how processes must be simplified and rebuilt for speed,• and why losing control—even briefly—can cost a company everything. 04:00 The Quest for Differentiation in Healthcare 09:21 AI Agents: Revolutionizing Clinical Tasks 12:42 Building a Reliable Knowledge Base 15:17 Ensuring Workflow Integrity in AI 19:46 Global Expansion Strategy of Quadrivia 22:58 Navigating Trust and Cultural Differences 26:04 Competing with Giants in the AI Space 30:22 Agility in Decision Making 31:15 Lessons from Babylon's Legacy 33:08 The Importance of Speed in Entrepreneurship 35:59 Navigating Failure and Success 39:44 Optimizing People, Product, and Processes 41:25 The Role of Luck in Entrepreneurship 47:14 The Birth of Quadrivia 49:04 Insights from Global Healthcare Markets www.facesofdigitalhealth.com http://fodh.substack.com/

In this episode of Faces of Digital Health, we sit down with Anne Forsyth, Hospital leader in clinical applications from Women's College Hospital in Canada, to explore how AI — especially generative AI — is reshaping daily clinical practice. Over the past two years, enthusiasm for AI has skyrocketed inside hospitals, with clinicians themselves requesting new tools rather than resisting them. We discuss the cautious but deliberate rollout of AI scribes, the still-emerging trust in decision-support AI, and the safety and change-management considerations that mirror (and sometimes exceed) traditional IT implementations. Anne offers an honest look at the financial challenges of sustaining AI tools in publicly funded health systems and shares practical advice for hospitals navigating funding models, clinical buy-in, and responsible innovation. Show notes: 01:50 – Current AI Implementations 03:21 – Safety and Risk Considerations 04:00 – Comparing AI Rollouts to Traditional IT Tools 05:10 – The Business Equation: Funding AI in Public Healthcare 06:20 – Advice for Hospitals on Sustainable AI Adoption 06:40 – Looking Ahead: The Future of AI in Clinical Applications www.facesofdigitalhealth.com https://fodh.substack.com/

In this Faces of Digital Health episode Dr. David Dodick, Chief Science and Medical Officer at the Atria Health Institute and Co-Chair of the Atria Research Institute talks about brain health, dementia prevention, the rapidly evolving science of Alzheimer’s, and how digital tools and AI are transforming care. We also cover why women face higher Alzheimer’s risk, the microvasculature’s role in cognition, and the biggest leap in migraine treatment: CGRP-targeting therapies. A must-watch if you’re curious about prevention, personalized risk, and which consumer tech is actually useful today. Dr. David Dodick trained at the Mayo Clinic and served on the faculty there for more than three decades. At the Mayo Clinic, he founded the Neurology Residency Program, the Headache Fellowship Program, the Sports Neurology and Concussion Program, the Migraine and Headache Program, and co-founded the Vascular Neurology/Stroke Program. What you’ll learn: 1. How much dementia is realistically preventable—and how to lower your risk 2. Why amyloid ≠ destiny, and what “biological vs. clinical” Alzheimer’s means 3. The role of sleep, hearing, blood pressure, metabolic health, and social connection 4. Smart wearables that matter (AFib, BP, CGM) and what’s just hype 5. How AI “diagnostic orchestrators” could supercharge clinicians and empower patients 6. Migraine red flags (when to go to the ER) and the CGRP revolution in treatment

Stephen Ryu, a neurosurgeon and key figure in the Stanford Neuroprosthetics Lab joins Tjaša Zajc on Faces of Digital Health to demystify brain–computer interfaces (BCIs): how they work, why invasive systems outperform non-invasive ones, realistic use cases (motor control and speech), timelines and durability, safety and MRI trade-offs, cybersecurity, business models, and what Paradromics is building as a high-bandwidth BCI platform. Throughout, Stephen separates science fact from sci-fi, stressing near-term potential to restore communication and movement for people living with paralysis, while noting earlier-stage areas like mental health and pain. What we cover: - Invasive vs. non-invasive BCIs, and why electrode proximity to neurons matters for performance - Decoding motor intent and speech: training, language considerations, and LLM-enabled synthesis - Safety, surgery, and durability (why 10-year implant lifespans are a meaningful target) - MRI/CT compatibility trade-offs (and parallels to pacemakers/DBS) - Cybersecurity realities (what BCIs can not do today) - Business models, regulation, and reimbursement paths for medical-grade BCIs - Paradromics’ differentiation: a high-bandwidth platform designed to scale across use cases - Future indications: pain, sensory restoration; earlier stage: mental health biomarkers - The human impact: restoring connection for people who can’t move or speak Chapters: 01:37 How BCIs work; signals, decoding, invasive vs. non-invasive 07:13 Surgery basics, risks, and why proximity boosts performance 09:36 Decoding speech & language considerations 13:31 What’s most advanced today: motor + speech 14:58 Mental health: biomarkers and why it’s early 17:48 Longevity, MRI/CT limits, realistic replacement intervals 21:16 Patient perception: fear, performance, and value vs. alternatives 25:04 Paradromics’ platform & high-bandwidth approach 29:22 Platform use cases by brain area (motor, auditory, etc.) 31:18 Cybersecurity: risks today vs. sci-fi 32:35 Business models, regulation, and access 36:42 Trials landscape; Paradromics’ timeline 37:53 Biggest concerns: hype vs. reality 39:50 Three things everyone should know about BCIs 42:10 Potential in pain management 44:41 Role of AI/ML in decoding and assistive apps 46:36 Final thoughts www.facesofdigitalhealth.com Newsletter: https://fodh.substack.com/