On the Mind with The Weill Cornell Medicine Department of Psychiatry

In this episode of On the Mind, host Dr. Daniel Knoepflmacher speaks with Dr. Dhruv Khullar, a hospitalist and Associate Professor of Population Health Policy and Economics at Weill Cornell Medicine and a contributing writer for The New Yorker, about the promise and peril of artificial intelligence in mental health care. Their conversation explores the rapid expansion of AI into clinical documentation, diagnostic reasoning, and patient navigation, as well as the risks of cognitive de-skilling, sycophantic chatbots, and profit-driven apps that cloak commercial motives in the language of clinical care. They also discuss how AI's simulation of empathy and relational interaction is hacking the fundamental human bonds of attachment, trust, and genuine connection that lie at the core of effective psychotherapy and healthy human development. Dr. Khullar shares his thinking on the regulatory frameworks and research infrastructure needed to help ensure these technologies serve patients rather than exploit them.

In this episode of On the Mind, host Dr. Daniel Knoepflmacher speaks with Dr. Alyson Gorun, a reproductive psychiatrist and Acting Director of the Aaron Stern, M.D., Ph.D. Program in Psychodynamic Psychiatry at Weill Cornell Medicine, about mental health during the perinatal period. Dr. Gorun discusses the psychiatric conditions most commonly associated with pregnancy and the postpartum months, how pre-existing diagnoses can be destabilized by hormonal and psychosocial changes, and the complex risk-benefit considerations that guide medication decisions. She also addresses the psychological weight of new parenthood, structural disparities in perinatal care, and evidence-based approaches to both pharmacological and psychotherapeutic treatment.

In this episode of On the Mind, host Dr. Daniel Knoepflmacher speaks with Dr. Jeff Ha, Associate Program Director of Weill Cornell Medicine's Consultation-Liaison Psychiatry Fellowship Program, about the diagnosis and treatment of delirium. Their discussion covers the diagnostic criteria for delirium, its clinical presentations across the hyperactive, hypoactive, and mixed subtypes, and the underlying neurobiological mechanisms that produce its characteristic waxing and waning course. Listeners will learn about the significant morbidity and mortality associated with delirium, with particular attention to the underrecognized danger of hypoactive delirium, the often prolonged and incomplete trajectory of recovery, and the demographic and cultural factors that shape both risk and diagnosis. The episode also explores the full spectrum of treatment as well as the psychological sequelae that can persist long after the acute episode resolves, including Post-Intensive Care Syndrome.

Dr. Ha reflects on the therapeutic value of family presence and the importance of psychoeducation for both patients and caregivers. This episode provides a comprehensive and clinically grounded guide to one of the most common and consequential conditions seen by psychiatrists in medical settings.

In this episode of On the Mind, host Dr. Daniel Knoepflmacher speaks with Dr. Jeff Ha, Associate Program Director of Weill Cornell Medicine's Consultation-Liaison Psychiatry Fellowship Program, about the diagnosis and treatment of delirium. Their discussion covers the diagnostic criteria for delirium, its clinical presentations across the hyperactive, hypoactive, and mixed subtypes, and the underlying neurobiological mechanisms that produce its characteristic waxing and waning course. Listeners will learn about the significant morbidity and mortality associated with delirium, with particular attention to the underrecognized danger of hypoactive delirium, the often prolonged and incomplete trajectory of recovery, and the demographic and cultural factors that shape both risk and diagnosis. The episode also explores the full spectrum of treatment as well as the psychological sequelae that can persist long after the acute episode resolves, including Post-Intensive Care Syndrome.

Dr. Ha reflects on the therapeutic value of family presence and the importance of psychoeducation for both patients and caregivers. This episode provides a comprehensive and clinically grounded guide to one of the most common and consequential conditions seen by psychiatrists in medical settings.

In this episode of On the Mind, host Dr. Daniel Knoepflmacher speaks with Dr. Jonathan Avery, Vice Chair for Addiction Psychiatry at Weill Cornell Medicine, about gambling disorder — a condition that is far more prevalent than most people recognize, yet frequently overlooked and misunderstood. Dr. Avery traces the history of gambling disorder as a diagnosis and explains the neurobiology behind why gambling can become addictive, including how it activates the brain’s reward pathways in ways that parallel substance use disorders. Their conversation explores how the explosive growth of online and sports betting has expanded the reach of problematic gambling, particularly among younger adults. Dr. Avery also discusses the warning signs clinicians and loved ones should watch for, the shame and secrecy that often delay help-seeking, and the full range of evidence-based treatments available, including psychotherapy, 12-step programs, and medications such as naltrexone and GLP-1 agonists. This episode offers a clinically grounded and compassionate look at a disorder that is hiding in plain sight.