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Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health

Joanne Kennedy
Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health
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  • 27. Why Blood Tests & Functional Medicine Tests Aren’t the Full Story: Gut, Histamines, Genes, Hormones & More!
    In this episode of The Histamine Well Podcast, host Joanne Kennedy and guest Mariella Gebhardt unpack the nuances of medical testing in functional medicine—and why lab results alone don’t always tell the full story.From histamine intolerance and methylation issues to gut health, Candida, mold exposure, and hormone imbalances, Joanne and Mariela explore the limitations and benefits of testing while emphasizing the importance of case history, symptoms, and environmental factors in shaping treatment.They break down popular tests—including organic acids tests (OAT), microbiome testing, genetic testing, thyroid panels, iron tests, and hormone testing—highlighting when they’re useful, what they may miss, and how to interpret them in real-world practice.Whether you’re curious about functional medicine, women’s hormones, SIBO, oxalates, DAO enzyme activity, or vitamin B12 deficiency, this episode offers clarity on when testing helps—and when it can be misleading.What You’ll Learn in This Episode:Why clinical context matters more than test results aloneHow to approach Candida, mold, and mycotoxin testingThe role of the DAO enzyme in histamine breakdownPitfalls of genetic and gene testing for methylationHow to interpret iron tests, thyroid panels, and hormone markersInsights on organic acids, oxalates, and gut health testingIf you’ve ever wondered whether your test results reflect the whole picture—or how to navigate functional medicine testing with confidence—this conversation will help you understand the bigger picture.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!
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  • 26. Mold & Chronic Illness: Symptoms, Testing, and Detox Strategies with Melanie Peers
    Could mold be the missing link in your chronic health puzzle?In this episode of The Histamine Well Podcast, Joanne speaks with Melanie Peers about the hidden impact of mold illness and how it can silently drive histamine intolerance, food sensitivities, and long-term inflammation.You’ll discover how mold exposure can:Raise histamine levels and trigger mast cell activationDisrupt methylation and detoxification pathwaysCause oxalate buildup and sulfur imbalancesLead to neurological, digestive, respiratory, and skin symptomsMelanie shares how to spot the difference between everyday mold allergies and systemic mold-related illness, how to test for mold in your home and body, and what a mold detox protocol can look like in real life.Whether you’re a health practitioner or someone struggling with unexplained symptoms, this episode gives you practical strategies for identifying mold, removing exposure, and supporting recovery.What You’ll Learn in This EpisodeKey symptoms of mold illness you might be missingHow mold drives histamine intolerance and CIRS (Chronic Inflammatory Response Syndrome)The mold–oxalate connection and why it matters for gut healthEffective mold testing for your home and bodyMold detox strategies and the role of sulfur in recoveryEnvironmental tips for reducing mold exposureReal-life case studies of mold-related illness and recovery✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!
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  • 25. Energy Healing Essentials for Perimenopause: A Discussion with Claire Tait
    Perimenopause isn’t just a physical transition — it’s an emotional, spiritual, and energetic shift. In this empowering episode of The Histamine Well Podcast, Joanne speaks with Claire Tait, a holistic kinesiologist and intuitive energy healer, about how to navigate perimenopause with greater balance, calm, and self-awareness.Claire shares her expertise on how kinesiology, reiki, acupressure, yoga, and other holistic practices can support women during this powerful life stage. You’ll learn how to regulate your nervous system, address anxiety naturally, and embrace the spiritual metamorphosis of perimenopause.This conversation is filled with practical rituals, personal insights, and empowering perspectives to help you surrender to the changes, reconnect with yourself, and thrive during midlife.What You’ll Learn in This Episode:Emotional & spiritual transitions of perimenopauseHow self-awareness supports hormonal and emotional healthKinesiology: blending Eastern and Western healing methodsReiki, acupressure, and yoga for grounding and calmNatural approaches to easing anxiety during perimenopauseThe role of the nervous system in healingHow intermittent fasting impacts women’s healthEmbracing aging and rejecting societal pressuresThe energetics of female empowerment✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!
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  • 24. Histamine & Anxiety – How High Histamine Triggers Fight-or-Flight Symptoms
    Can histamine be the hidden reason behind your anxiety?In this episode, I break down how histamine acts as a neurotransmitter in the brain — and why an overload can leave you wired, anxious, and unable to relax. We dive into how methylation, estrogen, mold, and gut inflammation (including SIBO and oxalates) all feed into the histamine-anxiety loop.Whether you're a practitioner treating patients with anxiety or someone who’s tried everything to feel better — this episode gives you a deeper lens into the hidden biochemical drivers of mental health symptoms.If you've ever felt overstimulated, panicked, or like anxiety hits out of nowhere, you're going to want to hear this one.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!
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  • 23. Could Your Histamine Intolerance Actually Be Sulfur Intolerance?
    We break down how disrupted sulfur metabolism can mimic histamine symptoms—severe bloating, crushing fatigue, joint pain, brain fog, skin flushing—and why reactions to garlic, onions, eggs, brassicas, NAC, and glutathione are key clues.You’ll learn the roles of sulfite/sulfide vs. sulfate, SUOX + molybdenum, B12, mitochondria, hydrogen sulfide overgrowth, and environmental drivers like mold and oxalates. We also cover testing pointers (homocysteine, stool, OAT), why low-sulfur diets are only a short-term tool, and practical next steps for practitioners and patients.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!
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About Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health

The Histamine Well is a podcast for health practitioners and patients alike, bridging the gap between complex science and practical understanding. With a focus on histamine, methylation, and related health topics, the show translates advanced concepts into actionable insights for practitioners while empowering patients with accessible, evidence-based knowledge.Your host, Joanne Kennedy, is a naturopath and expert in histamine intolerance, MTHFR, and methylation. She is also an author and runs an online group coaching program for practitioners and students on histamine and methylation. Jo loves breaking down complex science into clear, easy-to-understand language, offering practical tips and the latest insights to empower you to take charge of your health.
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