The Metabolic Link

• The Mitochondrial Link to Mental Illness | Ana Andreazza, PhD | The Metabolic Link Ep.63

  Mitochondria do more than power our cells—they may hold the key to understanding and treating mental illness.In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Ana Andreazza, a leading expert in mitochondrial health at the University of Toronto.Dr. Andreazza has pioneered research linking mitochondrial dysfunction to psychiatric disorders like bipolar disorder, utilizing groundbreaking 3D brain organoid models to study neurotransmission. She also leads research on mitochondrial transplantation, a potential game-changer in regenerative medicine.Join us as we explore how mitochondria influence mood, metabolism, and overall health—and why optimizing mitochondrial function may be the future of medicine. Listen to the episode on any major podcast player or watch the interview on YouTube.Learn more about Dr. Andreazza's work here.Special thanks to our sponsors:Genova Connect: Get 15% off any Genova Connect test kits by using the code METABOLICLINK hereFatty15: Get 15% off their 90-day subscription Starter Kit with the code METABOLICLINK hereMUD/WTR: Start your new morning ritual & get up to 43% off your MUDWTR with code METABOLICLINK herePuori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Visit this link and use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

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• Optimizing Metabolic Health | MHS Panel Discussion | The Metabolic Link Ep. 62

  Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here.What’s the best way to optimize metabolic health? In this powerhouse episode of The Metabolic Link, we bring together leading experts including Dr. Ben Bikman, Dr. Richard Johnson, Dr. Jonathan Jun, Dr. Nick Norwitz, and Dave Feldman from our Optimizing Metabolic Health Symposium filmed at Metabolic Health Summit 2024 and hosted by Dr. Dominic D'Agostino.In this discussion, you'll dive into some of the biggest questions in metabolism, including:What are the long-term effects of GLP-1 medications on fat, muscle, and metabolism?Does long-term dieting slow metabolism? And if so, can you reverse it?How do diet and fasting influence neuropathy and nerve function? Exercise and lipid profiles—what makes an athletic metabolism different?Do high-protein diets really harm the kidneys, or is it a myth?What is the role of the microbiome in weight gain, fat loss, and metabolic adaptation?And much more! With insights from top scientists and researchers, this episode is packed with takeaways for anyone looking to improve their metabolic health.Special thanks to the sponsors of this episode:Genova Connect: Get 15% off any Genova Connect test kits by using the code METABOLICLINK hereMaui Nui Venison: Gain access to a limited collection of our favorite Maui Nui products hereZocdoc: Visit this link to find and instantly book a top-rated doctorPuori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

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• Targeting Cancer Metabolism: The Future of Oncology | Dr. Tomás Duraj | The Metabolic Link Ep. 61

  What if we could target cancer at its metabolic core? In this episode of The Metabolic Link, Dr. Dominic D’Agostino is joined by Dr. Tomás Duraj, a physician and cancer metabolism researcher working alongside Dr. Thomas Seyfried.Dr. Duraj is the lead author of a groundbreaking review on ketogenic metabolic therapy for glioblastoma, bringing together leading experts to explore how metabolic strategies could reshape cancer treatment.In this deep-dive conversation, they discuss the bioenergetics of cancer, the role of mitochondria, the Warburg effect, and why targeting glucose and glutamine metabolism may be the key to making standard cancer therapies more effective.Whether you’re a researcher, clinician, or someone interested in the latest advancements in cancer therapy, this episode is packed with insights that could redefine the way we think about cancer treatment. Watch the full episode here or listen on your favorite podcast player for this must-hear discussion on the future of metabolic therapy for cancer!Read Dr. Duraj's paper: Clinical research framework proposal for ketogenic metabolic therapy in glioblastomaAbout Dr. Tomás DurajDr. Tomás Duraj is a Czech physician-scientist, receiving his Medical Degree from the Rey Juan Carlos University and his PhD in Translational Medicine from the CEU San Pablo University (Madrid, Spain). His research focuses on studying the potential of bioenergetic modulation in cancer metabolism, with special emphasis on glioblastoma, the most aggressive and lethal primary brain tumor. After developing cancer research at the team of Dr. Ayuso Sacido, he joined Dr. Thomas N. Seyfried’s laboratory in Boston College. His goal is to advance our understanding of metabolic oncology on a rigorous, evidence-based background, making it part of the standard oncology toolkit.Special thanks to the sponsors of this episode:Puori: Get 20% off Puori supplements at https://puori.com/METABOLICLINK and use the code METABOLICLINKFatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to https://fatty15.com/METABOLICLINK and use code METABOLICLINK.MUDWTR: Get up to 43% off with code METABOLICLINK at https://mudwtr.com/METABOLICLINKIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

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• A Ketogenic Approach to Type 1 Diabetes | Dr. Ian Lake | The Metabolic Link Ep.60

  Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.com Can a ketogenic diet revolutionize the management of type 1 diabetes? In this episode of The Metabolic Link, Dr. Ian Lake, a UK-based physician and type 1 diabetes advocate, shares his personal and professional journey in using low-carb and ketogenic diets to improve metabolic control.Diagnosed with type 1 diabetes at 36, Dr. Lake initially followed conventional high-carb recommendations—until he discovered the power of nutritional ketosis. He breaks down how reducing insulin volumes, optimizing glucose levels, and becoming fat-adapted transformed his health and life.From running 700 miles while following a ketogenic diet to leading type 1 diabetes retreats, Dr. Lake shares actionable insights on metabolic flexibility, insulin sensitivity, and the real-world implications of a ketogenic approach.Special thanks to the sponsors of this episode:Puori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Visit https://puori.com/METABOLICLINK and use the code METABOLICLINKMaui Nui Venison: Gain access to a limited collection of Dom’s favorite Maui Nui products at https://mauinuivenison.com/METABOLICLINKZocdoc: Visit https://Zocdoc.com/METABOLICLINK to find and instantly book a top-rated doctorIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

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• Chad Vanags | Patient Perspective: Why I Don’t Trust You & How We Can Fix It | The Metabolic Link Ep.59

  Become a member of The Metabolic Initiative to access exclusive ad-free episodes, watch 100s of videos on metabolic health, and earn CMEs here.In this powerful and unfiltered episode of The Metabolic Link, we're sharing a full presentation by Chad Vanags, a former SaaS executive and entrepreneur who has turned his stage 4 lung cancer diagnosis into a mission to reshape the way we think about healing. Recorded live at Metabolic Health Summit in January of 2024, Chad shares his journey of becoming metabolically, physically, and mentally elite in the fight against cancer.Through his deeply personal story, Chad provides a rare and essential patient perspective, shedding light on the gaps in traditional cancer care—from nutrition and communication to the importance of mindset and metabolic health. His insights challenge clinicians, researchers, and patients alike to rethink the medical status quo, spark innovation, and inspire transformative conversations.This episode is more than just a story of resilience—it’s a call to action to integrate patient voices into the heart of healthcare and foster a collaborative approach to healing.Listen to this episode or watch on YouTube to explore Chad’s journey, the lessons he’s learned, and his hope for the future of patient-centered care.Special thanks to the sponsors of this episode:Fatty15: Get 15% off their 90-day subscription Starter Kit with the code METABOLICLINK at fatty15.com/METABOLICLINKMUD/WTR: Start your new morning ritual & get up to 43% off your MUDWTR with code METABOLICLINK at mudwtr.com/METABOLICLINKIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

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