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Your Brain On

Podcast Your Brain On
Drs. Ayesha and Dean Sherzai
A podcast about the neuroscience of everything. From neurologists, researchers, and public health advocates Drs. Ayesha and Dean Sherzai, explore every aspect o...
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5 of 35
  • Your Brain On... Ketamine
    For decades, ketamine has mainly been used as an anaesthetic, but in more recent years, it’s gained popularity in mental health treatment. Conversations around the benefits and risks associated with its therapeutic usage ignited towards the end of 2023, when actor Matthew Perry, star of the sitcom ‘Friends’, died from the acute effects of the ketamine he was using to treat anxiety. In this episode of ‘Your Brain On...’, we discuss: • The neurochemical mechanisms of ketamine, and its interplay with depression • What we know about the opportunities and pitfalls of using ketamine in mental health treatment • The potential for ketamine use in reducing the impacts of neurodegenerative diseases like Alzheimer’s and Parkinson’s • How technology and improvements in passive and active data collection are helping us better understand how ketamine affects cognition and neuroplasticity • The history of ketamine’s use as an antidepressant • How ketamine is actually administered, through various dosages and courses of treatment We’re welcoming two of the leading figures in this space to the podcast: Dr. Gerard Sanacora, who is a Professor of Psychiatry at Yale University and the Director of the Yale Depression Research Program, and Dr. John Krystal, also from Yale: a Professor of Psychiatry, Neuroscience, and Psychology. This is... Your Brain On Ketamine. ‘Your Brain On’ is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Ketamine’ • SEASON 4 • EPISODE 2 ——— LINKS DR. GERARD SANACORA Dr. Sanacora at Yale: https://medicine.yale.edu/profile/gerard-sanacora/ The Yale Depression Research Program: https://medicine.yale.edu/psychiatry/depression/ DR. JOHN KRYSTAL Dr. Krystal at Yale: https://medicine.yale.edu/profile/john-krystal/ ——— FOLLOW US Join the NEURO Academy: NEUROacademy.com Instagram: @thebraindocs Website: TheBrainDocs.com More info and episodes: TheBrainDocs.com/Podcast
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  • Your Brain On... Sex
    From the first spark of attraction, all the way to climax, sex sets off chemical fireworks in your brain. And yet, this beautiful, powerful act has become mired in shame and stigma. But through open conversation and deeper scientific understanding, we can cast off those shackles, and even embrace sex as a marker for cognitive and overall health. In this episode of ‘Your Brain On...’ — our Season 4 debut! — we discuss: • The neurological processes involved with sex, arousal, attraction, and desire • Why studying the cognitive effects of sexual stimuli can be so complicated • How our relationship with sex is altered as we age, and is affected by periods of change like menopause • The neuroscientific differences between masturbation and sex with a partner • The complex debate about pornography consumption, and the need for better sex education • The links between brain health, heart health, mental health, and sexual health • The benefits of good nutrition, exercise, and stress management for sexual health • Motivations and methods for freeing conversations about sex from stigmas and taboos — especially for women Joining us for this immensely important conversation are two fantastic guests: sexual behaviour expert and data scientist Dr. Nicole Prause, and sexual medicine expert and urogynecologist Rena Malik. This is... Your Brain On Sex. ‘Your Brain On’ is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Sex’ • SEASON 4 • EPISODE 1 (SEASON 4 DEBUT) — LINKS Dr. Nicole Prause at UCLA: https://www.uclahealth.org/departments/medicine/gastro/research/labs-and-programs/patel-laboratory Dr. Nicole Prause on Twitter: https://x.com/nicolerprause Dr. Nicole Prause on Bluesky: https://bsky.app/profile/nicolerprause.bsky.social Dr. Rena Malik’s website: https://renamalikmd.com/ Dr. Rena Malik on YouTube: https://www.youtube.com/@RenaMalikMD Dr. Rena Malik on Instagram: https://www.instagram.com/renamalikmd/ — FOLLOW US Join the NEURO Academy: NEUROacademy.com Instagram: @thebraindocs Website: TheBrainDocs.com More info and episodes: TheBrainDocs.com/Podcast  
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  • Your Brain On... Protein
    Protein — how much do we need? What’s the healthiest way to consume it? Can we get enough from plant-based diets? Until recent decades, protein hasn’t been quite as prominent in public health discussions as sugar and fats.  However, with longer lifespans emphasizing the importance of protein for long-term health, and growing confusion around the quality and quantity of protein needed, it has become a highly debated macronutrient. In ‘Your Brain On… Protein’, we explore: • The brain health benefits (and general health benefits) of protein • Plant-based protein vs. meat protein, and supplements like protein powders • How much protein we really need to eat every day • Ways we can all introduce more protein into our diets • Why ‘health’ influencers are suddenly recommending unusually  high levels of protein consumption • How we measure the quality of proteins, including digestibility and absorption In this episode, we’re joined by two fantastic nutrition experts: DR. MATTHEW NAGRA, nutritionist and science communicator. DR. ALAN FLANAGAN, esteemed nutrition scientist (previously featured in ‘Your Brain On… Sugar’ and ‘Your Brain On… Fats’ ‘Your Brain On’ is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. Drs. Ayesha and Dean are now welcoming patients via the Brain Health Institute: https://brainhealthinstitute.com/ ‘Your Brain On... Protein’ • SEASON 3 • EPISODE 10 (SEASON 3 FINALE!) ——— LINKS: Dr. Matt Nagra Instagram: https://www.instagram.com/dr.matthewnagra Website: https://drmatthewnagra.com/  Dr. Alan Flanagan Alan on Instagram: https://www.instagram.com/thenutritionaladvocate Alinea Nutrition: https://www.alineanutrition.com/ ——— REFERENCES: Dietary Patterns and Risk of Dementia: a Systematic Review and Meta-Analysis of Cohort Studies. https://doi.org/10.1007/s12035-015-9516-4 Dietary fat composition and dementia risk. https://doi.org/10.1016/j.neurobiolaging.2014.03.038 Dietary Protein and Amino Acids in Vegetarian Diets—A Review. https://pmc.ncbi.nlm.nih.gov/articles/PMC6893534/ Animal vs Plant-Based Meat: A Hearty Debate. https://pubmed.ncbi.nlm.nih.gov/38934982/ High-Protein Plant-Based Diet Versus a Protein-Matched Omnivorous Diet to Support Resistance Training Adaptations: A Comparison Between Habitual Vegans and Omnivores. https://pubmed.ncbi.nlm.nih.gov/33599941/ Vegan and Omnivorous High Protein Diets Support Comparable Daily Myofibrillar Protein Synthesis Rates and Skeletal Muscle Hypertrophy in Young Adults. https://pubmed.ncbi.nlm.nih.gov/36822394/ Digestibility issues of vegetable versus animal proteins: protein and amino acid requirements--functional aspects. https://pubmed.ncbi.nlm.nih.gov/23964409/ Soy and Isoflavone Consumption and Multiple Health Outcomes: Umbrella Review of Systematic Reviews and Meta-Analyses of Observational Studies and Randomized Trials in Humans. https://doi.org/10.1002/mnfr.201900751 No Difference Between the Effects of Supplementing With Soy Protein Versus Animal Protein on Gains in Muscle Mass and Strength in Response to Resistance Exercise. https://pubmed.ncbi.nlm.nih.gov/29722584/ Neither soy nor isoflavone intake affects male reproductive hormones: An expanded and updated meta-analysis of clinical studies. https://pubmed.ncbi.nlm.nih.gov/33383165/ The health effects of soy: A reference guide for health professionals. https://pmc.ncbi.nlm.nih.gov/articles/PMC9410752/ The Effect of Plant-Based Protein Ingestion on Athletic Ability in Healthy People—A Bayesian Meta-Analysis with Systematic Review of Randomized Controlled Trials. https://www.mdpi.com/2072-6643/16/16/2748 Effects of high-quality protein supplementation on cardiovascular risk factors in individuals with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials. https://doi.org/10.1016/j.clnu.2024.06.013 Vegan and Omnivorous High Protein Diets Support Comparable Daily Myofibrillar Protein Synthesis Rates and Skeletal Muscle Hypertrophy in Young Adults. https://pubmed.ncbi.nlm.nih.gov/36822394/
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  • Your Brain On... Misinformation
    The digital age has made it easier than ever to access health information, but how can we know which sources to trust? Social media is saturated with misinformation. Some of it is inadvertent — many bold pseudoscientific claims seem very convincing, and anyone could be forgiven for sharing it with the best intentions. But, a more deliberate manipulation of scientific information has become commonplace, often used to push certain narratives or turn a profit. Combating this misinformation machine can feel impossible. So, we assembled five experts from different corners of the science communication community to help equip you for the fight: Dr. David L. Katz, MD, MPH, a renowned figure in the field of preventive medicine, public health, and nutrition. (Website: https://davidkatzmd.com/) Steven Novella MD, clinical neurologist and associate professor at Yale University School of Medicine, a host of The Skeptics' Guide to the Universe podcast, and a founder of the New England Skeptical Society. (Website: https://theness.com/neurologicablog/) Dr. Jessica Steier PhD, public health scientist and host of the wildly popular Unbiased Science podcast. (Instagram: https://www.instagram.com/unbiasedscipod) Dr. Jonathan Stea PhD,  clinical psychologist and author of the book ‘Mind the Science’. (Instagram: https://www.instagram.com/dr_jonathan_stea/ / Website: https://www.jonathanstea.com/) Dr. Idrees Mughal, AKA ‘Dr. Idz’, one of the most popular online misinformation-debunking social media icons. (TikTok: https://www.tiktok.com/@dr_idz / Website: https://www.schoolofdridz.com/) Together, we discuss: • The telltale signs of pseudoscientific messaging. • Where misinformation comes from, and why it often spreads faster than evidence-based facts. • Why we can be so susceptible to believing misinformation. • Who profits by poisoning the science communication space. • How we can improve our scientific literacy and avoid echo chambers. • Ways academics can improve their public health communication. • ‘Your Brain On’ is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Misinformation’ • SEASON 3 • EPISODE 9
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  • Your Brain On: A Brain Health Revolution Summit Special
    20 incredible conversations with leading scientists, in one hour. We’re excited to present this special installment of Your Brain On, featuring highlights from some of the speakers talking at our first ever Brain Health Revolution Summit. Our first summit, running September 30 through October 6 2024, features seven days of hour-long discussions with the scientists who are actually conducting the studies, publishing the papers, and pushing public health policy reforms that are shaping our world. No matter when you’re listening to this episode, visit https://bhrsummit.com/ for more information about the summit — be it our first 2024 edition, or a future installment! Day 1: The Brain Health Landscape: From Insights to Action Day 2: Mental Health Matters and Heart Health for a Stronger Brain Day 3: Women’s Brain Health: Hormones, Longevity, and Vitality Day 4: Emerging Challenges in Brain Health Day 5: Fuel for Thought: Nutrition, the Gut, and the Brain Day 6: Move, Breathe, Thrive: Exercise and Stress Management Day 7: Recharge and Optimize: Sleep and Cognitive Performance This special episode includes excerpts of our conversations with:  Rachel Dolhun, MD Michael Okun, MD Charles DeCarli, MD Ari Tuckman, PsyD Amishi Jha, PhD Danielle Belardo, MD Margarett McCarthy, PhD Lisa Mosconi, PhD Lisa Genova Idrees ‘Dr. Idz’ Mughal, MBBS, MRes, DipIBLM Daniele Piomelli, PhD Frank Lin, MD, PhD Alan Flanagan, PhD Matthew Nagra, ND Stuart Phillips, PhD Natali Edmonds, PhD Satchin Panda, PhD Donn Posner, MD Sujay Kansagra, MD Yaakov Stern, PhD For more information about the Brain Health Revolution Summit, visit: https://bhrsummit.com/  The Brain Health Revolution Summit 2024 is presented in partnership with Healthy Minds Initiative: thymindsinitiative.org ‘Your Brain On’ is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai.
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