LONGEVITY with Nathalie Niddam

📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/.

Today, I’m joined by Dr. Henry Mahncke, an innovative neuroscientist and the CEO of BrainHQ, who has dedicated over two decades to uncovering the powerful ways targeted training can help the brain process information faster and more efficiently. In our conversation, Dr. Mahncke shares his deeply personal motivation behind this work, recalling early experiences with his grandfather’s cognitive decline and how witnessing that loss inspired a lifelong mission to challenge outdated beliefs about the aging brain.

Visit BrainHQ.com/nat, and register for free with no credit card and receive one exercise per day, plus access to the BrainHQ brain-health blog.

Episode Timestamps:

The brain is not a fixed organ ... 00:00:00
Personal story: family and early memories of dementia ... 00:06:06
Origins of the myth that adult brains can’t change ... 00:08:30
Breakthrough research on neuroplasticity at UCSF ... 00:09:29
How processing speed underpins healthy cognitive function ... 00:16:37
Noisy, slow processing as a hallmark of aging brains ... 00:18:14
Speed training to synchronize and strengthen neural networks ... 00:19:32
Brain training as underlying “strength training” for cognition ... 00:20:40
Problems with current dementia research funding priorities ... 00:21:33
ACTIVE study: speed training reduces Alzheimer’s risk ... 00:24:46
Everyday, real-world benefits of brain training ... 00:28:04
Why brain training isn’t just crosswords and games ... 00:30:00
Neurochemistry of attention, reward, and adaptive challenge ... 00:31:16
Scientific rigor and industry skepticism ... 00:56:53
Expanding use: from seniors to athletes and special forces ... 01:00:12
Personal evolution in thinking about brain health ... 01:03:29
Brain training as an essential pillar for longevity ... 01:06:42

Learn more from Dr. Henry Mahncke below:

Website: BrainHQ.com/nat

LinkedIn: https://www.linkedin.com/in/henry-mahncke-3b89072/

Youtube: https://www.youtube.com/brainhq

Our Amazing Sponsors:

LongeFera by Regenerive - A precision-formulated ashwagandha supplement that isolates four key bioactive compounds to support a healthy stress response, cognitive function, balanced inflammation, and cellular longevity—without the fillers and inconsistent extracts found in many products. Head to regenerive.co and use code NAT25 for 25% off your order.

Countdown Insiders by Countdown — Join a community helping fund groundbreaking mitochondrial research while receiving exclusive events, science briefings, partner perks, and a voice in what Countdown does next. Get your first month free with code NATHALIE at joincountdown.org/membership.

Vampire Exosomes by Young Goose — an easy twice-daily serum designed to support smoother-looking, firmer, more hydrated, radiant skin, with 3 trillion quantified exosomes per bottle and a 90-day user study showing reported improvements in overall skin quality and fine-line smoothness. CLICK HERE and use code NAT10 to save on Vampire Exosomes.

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Dr. Bill Lawrence Episode

Today, I'm joined by Michael Feldstein, founder of Jasper and co-founder of Kindling Academy, who has spent years sounding the alarm about the hidden dangers lurking in our indoor air. Michael has a unique ability to connect the dots between our everyday exposures—to things like synthetic fragrances, mold, and poor air quality—and our long-term health, performance, and even the well-being of our children.

Go to http://Jaspr.co/nat and use code NAT for the next two weeks for $350 dollars off!

Learn more from Michael Feldstein below:

Website: https://Jaspr.co/nat

Instagram: https://www.instagram.com/jasprco/?hl=en

Episode Timestamps:

Welcome, guest intro, and focus on reducing environmental toxins ... 00:00:00
Rising awareness of indoor air and fragrance toxicity ... 00:06:07
Synthetic fragrance compared to secondhand smoke ... 00:10:18
Labeling, hidden chemicals, and home fragrance exposures ... 00:14:06
Market trends: Americans spend more to pollute air than clean it ... 00:17:19
Cumulative toxic exposures and easy home interventions ... 00:23:23
Steps for better sleep and air quality without big spending ... 00:25:14
Air quality often ignored in wellness and medicine ... 00:29:31
Selecting monitors and purifiers that actually work ... 00:40:54
Kindling Academy: principles of a healthier school ... 00:45:57
Air quality, absenteeism, and school performance ... 00:51:01
Empowering children through environment and agency ... 01:00:00
Balanced prevention vs. fear in wellness ... 01:03:00

Our Amazing Sponsors:

Metabolic Support Bioregulator Stack by Nature’s Marvels - A coordinated three-part system supporting vascular function, pancreatic metabolic signaling, and liver nutrient processing—because metabolism is a whole-body conversation, not a one-ingredient problem. Bioregulators from Nature’s Marvels are now available in the U.S.; Click HERE and use code NAT15 for 15% off your first order.

Magnesium Breakthrough Advanced 10 by BIOptimizers - A comprehensive magnesium formula with 10 bioavailable forms, active vitamin B6, and ionic trace minerals designed to support sleep, relaxation, recovery, stress, and metabolic health. Head to bioptimizers.com/bionat and use code BIONAT for 15% off, exclusive bonuses, and free shipping on select orders.

PW1 Grass-Fed Whey Protein by Puori - A clean, travel-friendly protein powder with 21 grams of protein, just five ingredients, and real Madagascar Bourbon Vanilla, with every batch third-party tested against 200+ contaminants. Go to puori.com/NAT and use code NAT for 32% off when you start a subscription, plus a free $30 shaker.

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Original Instagram

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Dr. Bill Lawrence Episode

📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/.

This week, I’m bringing you a special episode—a quarterly recap packed with some of the most fascinating conversations I’ve had recently on the future of health and longevity. From cutting-edge personalized skincare and breakthroughs in genetic responses to GLP-1 medications, to what you can really do about microplastics in your body, these are moments that genuinely excited me about where we’re headed.

Listen to the FULL episodes Mentioned:

From ‘Tan Maxing’ To The Growing Debate Over Sunscreen I Dr. Teo Soleymani I Ep #453

Personalizing GLP-1 Medications: The Role of Genetics in Weight Loss I Dr. Noura Abul-Husn I Ep #465

Microplastics: The INVISIBLE Threat | Heather Hutchens & Dr. Debra Kimless | Ep #470

3 Simple Habits to Reverse Aging Eyes I Dr. Bryce Appelbaum, OD, FOVDR I Ep #475

Breast Cancer: The Hidden COSTS And Radical Resilience I Dr. Laura James I Ep #466

The Revolutionary Case for NATURAL GLP-1s | Fat Loss Without Muscle Loss I Sarah Kennedy I Ep #477

Episode Timestamps:

Welcome and episode recap intro ... 00:00:00
Dr. Teo Soleymani: future of personalized skincare ... 00:05:12
Personalized genomics in dermatology and oncology ... 00:06:53
Emerging stem cell and anti-aging skin treatments ... 00:07:27
Precision dermatology and personalized approaches ... 00:09:37
Dr. Nora Abdul-Hussein: genetic variation in GLP-1 response ... 00:10:13
GLP-1 receptor gene and weight loss/nausea findings ... 00:11:19
Dosing implications and setting expectations for GLP-1s ... 00:13:14
Combining genetic and clinical factors in personalized care ... 00:15:44
Avoiding genetic determinism in medical language ... 00:17:03
Microplastics: widespread exposure and reducing risks ... 00:19:33
Emotional impact and hope for change in food systems ... 00:21:43
Bryce Applebaum: distinction between vision and eyesight ... 00:25:29
Preventing and reversing age-related vision decline ... 00:26:53
Women’s health, breast cancer, and self-care challenges ... 00:30:15
Feminist issues and autonomy in cancer care ... 00:31:45
Cancer as an opportunity for post-traumatic growth ... 00:36:25
Sarah Kennedy: clinical trials on natural appetite regulation ... 00:38:13
Long-term effects and usage patterns of Calocurb ... 00:39:14
Gut-brain axis, hunger hormones, and behavioral change ... 00:40:19

Our Amazing Sponsors:

GLP-1s From Collective - makes doctor-prescribed compounded GLP-1s more affordable, with medication starting at $59 a month at every dose, plus real-doctor messaging and licensed nutritionist support—without locked-in subscriptions or surprise price jumps. Start your 21-day free trial at collective.org/NAT.

Sunlighten’s mPulse Intelligent Sauna - lets you personalize your sauna sessions with independently controlled far-, mid-, and near-infrared wavelengths, goal-based programs, and the new Amplify RED for higher-heat, full-spectrum sessions. Save up to $2,100 plus free shipping at sunlighten.com with code NATLONGEVITY.

NMN+G Rx Advanced Formula by Wizard Sciences - combines NMN, Panax ginseng-derived ginsenosides, and apigenin to support healthy NAD+ levels and cellular energy. Click HERE and use code NAT15 for 15% off.

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Dr. Bill Lawrence Episode

📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/.

Today, I’m joined by the insightful Dr. Victoria Mazzei, an integrative medicine physician and author of Heal Faster, for a conversation that’s all about practical recovery—when real life throws you a curveball. Dr. Mazzei brings decades of clinical wisdom to the table, blending cutting-edge science with the fundamentals of what our bodies actually need to heal after surgery, illness, or injury. She opens up about the untapped potential of preparing your body—physically, emotionally, and nutritionally—well before you ever reach an operating room.

Episode Timestamps:

Introduction: Extending Healthspan and Episode Focus ... 00:00:00
Prehabilitation: preparing body and mind for surgery ... 00:05:07
Why supplements are stopped before surgery ... 00:06:31
Building resilience with nutrition, sleep, and fitness ... 00:07:29
Starting healing before surgery with protein and micronutrients ... 00:07:54
Managing anesthesia, pain, and non-opioid strategies ... 00:09:54
Integrative pain solutions: acupuncture, imagery, and devices ... 00:11:30
Science behind prehab for faster and safer recovery ... 00:13:04
Physical, emotional, and nutritional pre-op readiness ... 00:14:41
Psychological prep for breast cancer and cardiac surgery ... 00:20:43
Role of food sensitivities and elimination diets ... 00:28:20
Reversing frailty: protein and resistance training ... 00:37:47
Essential amino acids and antioxidants for healing ... 00:41:09
Supplements to avoid and importance of transparency ... 00:46:19
When to restart supplements after surgery ... 00:51:11
Inflammation's healing role, and when to use ice ... 00:54:05
Environmental toxins, hormone disruption, and healing ... 01:00:11
Detox principles: reduce exposure, support elimination ... 01:06:28
Vagus nerve, stress, and enhancing recovery with breathwork ... 01:09:25

Learn more from Dr. Victoria Maizes below:

Website: https://www.drvictoriamaizes.com/

Website: https://awcim.arizona.edu/body_of_wonder.html

Website: https://awcim.arizona.edu/publicListingSearch/fip.html

Our Amazing Sponsors:

Mitopure Gummies by Timeline – Supports healthier cellular energy, muscle strength, recovery, and healthy aging with clinically proven Urolithin A—without artificial sweeteners, colors, flavors, or unnecessary fillers. Head to timeline.com/nat20 to get Mitopure starting at just $99 and save an additional 20% on your order.

GHK-Cu Skin Cell Restorative Serum by Vitali - These copper peptide formulas support collagen, elasticity, skin recovery, and mature skin, and can be paired with Vita Zero Age Exosome Complex for a more complete regenerative skincare routine. Head over to VitaliSkincare.com and use code NAT20 for 20% off your order.

VO2-MAX and Crevolution by LVLUP Health — a smart longevity-focused pairing to support oxygen use, exercise resilience, muscle energy, strength, recovery, and cognitive performance. CLICK HERE and use code NAT for 15% off your order.

Nat's Links:

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Original Instagram

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Dr. Bill Lawrence Episode

📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/.

Today, I’m joined by the extraordinary Dr. Richard Horowitz, a board-certified internist, renowned Lyme disease specialist, and the author of Ending Chronic Illness—a book that’s become my new favorite reference guide for understanding the true roots of chronic disease. Dr. Richard Horowitz opens up about his journey from treating diabetes in upstate New York to becoming a medical detective in the heart of the country’s largest Lyme-endemic area, where standard medical training simply wasn’t enough. Patient by patient, he pieced together a radical new model for uncovering where inflammation really comes from—one that’s now transforming lives well beyond Lyme.

Take this FREE Questionnaire https://cangetbetter.com/symptoms/ to determine your likelihood of having Lyme and associated tick-borne disorders. His book then lays out what kind of testing and care could help.

Episode Timestamps:

Episode introduction and guest background ... 00:00:00
How Dr. Horowitz’s approach began with key patient cases ... 00:04:59
Developing the 16-point MSIDS model for inflammation ... 00:09:39
Impact of emotional trauma and mind-body connection ... 00:13:11
Addressing vagus nerve dysfunction and healing ... 00:15:22
Overlap among chronic diseases and resilience ... 00:24:41
The 16 factors behind chronic illness ... 00:25:32
Accelerated aging and inflammaging ... 00:27:13
Can healing reverse biological age? ... 00:28:06
Understanding inflammation’s dual role ... 00:33:08
Immune dysfunction and chronic illness ... 00:34:38
Annual checkups: new biomarkers and prevention ... 00:37:24
Alzheimer’s disease, infection, and amyloid ... 00:47:48
Practical use of the MSIDS model for symptoms ... 00:58:34
Essential lifestyle habits for healthspan ... 01:16:59

Learn more from Dr. Richard Horowitz below:

Website: https://cangetbetter.com/

Symptoms Questionnaire:  https://cangetbetter.com/symptoms/

Our Amazing Sponsors:

Quantum Upgrade - This 24/7 energy service is backed by placebo-controlled research, including a 256-channel EEG and HRV study that found lower stress-linked brainwaves and improved markers of stress adaptability during 5G exposure. Try it free for 15 days—no credit card required—at quantumupgrade.io/NAT and use code NAT15.

Stress Relief Kit by BEAM Minerals - A thoughtfully designed mineral-support system for busy, active, and stressful seasons, with liquid fulvic and humic complexes plus Electrolyze, Micro-BOOST, Happy-Lytes, and BooBoo-Lytes for everyday hydration and recovery. Head to beamminerals.com/NAT20 and use code NAT20 for 20% off your first order.

Probiotics + Digestive Bitters by Just Thrive - This gut-health pairing combines a spore-based probiotic designed to arrive alive in the gut with pre-meal bitters to support more comfortable digestion and less bloating. Buy a 90-day supply of probiotics and get three months of Digestive Bitters free—a $90 value—at JustThriveHealth.com/nat20 with code NAT20.

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Dr. Bill Lawrence Episode