LONGEVITY with Nathalie Niddam

Today, I'm joined by Dr. Aimie Apigian, an innovative leader in the biology of trauma, whose work bridges the worlds of science, medicine, and lived experience. In our conversation, Dr. Apigian opens up about her journey from conventional medicine—where symptom management was the norm—to uncovering the physiological roots of trauma and the crucial role our nervous system plays in resilience and healing. She shares how her own health struggles, her work with adopted children, and a relentless curiosity led her to re-examine everything she thought she knew about stress, autoimmunity, and capacity.
The 7-Day Somatic Healing for Stored Emotions - https://traumahealingaccelerated.mykajabi.com/a/2148170319/wdrhGYaY
21-Day Journey, a daily live session program that helps participants understand how much trauma their body may be holding - https://traumahealingaccelerated.mykajabi.com/a/2147704575/wdrhGYaY

Episode Timestamps:
Introduction, host's mission, and episode theme ... 00:00:00
Science behind trauma, limits of traditional medicine, and autoimmune experiences ... 00:06:11
Attachment, symptom management, functional medicine, and healing journey ... 00:08:17
Mold exposure, state triggers, brain inflammation, and capacity blocks ... 00:14:22
Medical gaslighting, trauma validation, and biological capacity ... 00:18:25
Safety, resilience, and chronic survival state effects ... 00:19:32
Misconceptions about chronic stress—emergency brake and vagus nerve ... 00:22:27
Attachment patterns, autoimmunity, and shrinking world ... 00:28:47
Chronic survival loop, exhaustion, coping strategies, and shutdown ... 00:31:11
Moving to repair: phases of healing and gentle approaches ... 00:34:08
Somatic practices, art therapy, and different expressions of trauma ... 00:39:01
Shifts in sleep, digestion, anxiety, and felt safety ... 00:42:06
Tracking nervous system state: strategies and awareness ... 00:46:41
Therapy limitations: biology and somatic integration ... 00:48:42
Retraining vs. managing symptoms, stabilization, and healing ... 00:54:53
Capacity, resilience, lessons from centenarians, and longevity ... 01:00:06
Trauma's impact on mitochondria, telomeres, and generational health ... 01:06:27
Gut microbiome and trauma: two-way connection ... 01:08:03
 
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Mitopure Longevity Gummies by Timeline — Clinically backed Urolithin A supports mitochondrial health to boost energy, recovery, and healthy aging, all in an easy daily gummy instead of another pill; go to timeline.com/nat20 for 20% off Mitopure Gummies.
 
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Dr. Bill Lawrence Episode

Today, I'm joined by the inspiring Leslie Kenny, Oxford-based longevity expert and a living example of turning adversity into vitality. After being told at 39 that she had lupus, rheumatoid arthritis, and just five years to live, Leslie defiantly forged a new path—reversing her diagnoses, restoring her thyroid health, and even welcoming a healthy baby girl at 43. Her story is a testament to the power of questioning the status quo, honoring the wisdom within our bodies, and refusing to accept decline as inevitable.
 
Leslie has a generous offer for you, when you visit oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout you'll get 20% off.
 
Episode Timestamps:
Welcome, show intro, and overview ... 00:00:00
Leslie Kenny's health journey and reversing disease ... 00:00:30
Biological vs. chronological age and the immune system ... 00:04:55
Impact of trauma and stress on aging ... 00:11:51
Overcoming prognosis: lifestyle and scientific interventions ... 00:18:02
Diet, tracking, and removing triggers ... 00:22:21
The overlooked importance of thyroid health ... 00:32:23
Dangers of overdoing fasting and hormesis ... 00:40:21
Autophagy basics and the cellular cleanup crew ... 00:44:06
Spermidine's role, sourcing, and supplement quality ... 01:10:19
 Optimizing longevity habits and daily routines ... 01:29:44
 
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Dr. Bill Lawrence Episode

Today, I'm joined by the extraordinary Dr. Natalie Yivgi-Ohana, a pioneering scientist whose passion for mitochondria unlocks new frontiers in longevity medicine. Our conversation truly blew my mind—Dr. Yivgi-Ohana brings decades of expertise to demystify these tiny, ancient powerhouses that fuel every cell in our bodies, impact our hormones, drive immunity, and, as it turns out, play a central role in how we age.
 
Episode Timestamps:
Welcome to the Longevity Podcast and today's focus on mitochondria ... 00:00:00
Maternal inheritance and critical functions of mitochondria ... 00:05:56
Mitochondria as energy producers and hormone regulators ... 00:07:03
Aha moments: mitochondria control life, death, and disease ... 00:08:55
Endosymbiotic theory: how mitochondria originated ... 00:10:19
Chronic disease, aging, and the connection to mitochondria ... 00:16:10
Substrate fuels: carbs, fats, and importance of metabolic flexibility ... 00:20:18
Mitochondria's control over immune system and signaling ... 00:26:39
Mitochondrial transfer: how cells share organelle "powerhouses" ... 00:32:42
Groundbreaking therapy: transplanting mitochondria for rare diseases ... 00:36:40
Expanding mitochondrial therapies to age-related diseases ... 00:42:57
Aging in women: hormones, mitochondria, and inflection points ... 00:51:00
Stem cell exhaustion and cellular renewal ... 00:52:24
Biomarkers: ways to measure mitochondrial health ... 01:03:11
Supplements, lifestyle, and emotional health for mitochondria ... 01:15:47
Medication choices and minimizing mitochondrial toxicity ... 01:24:04
 
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O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off.
 
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Dr. Bill Lawrence Episode

Today, I'm joined by the insightful Courtney Van Bussum, a biomedical engineer and entrepreneur who has become a rising force in longevity science. Courtney shares how growing up in a family of healthcare innovators shaped her journey, and how she pivoted from startup life to tackling age-related challenges—especially when COVID brought her back to her roots and reignited her passion for cellular health.


If you want to try Endotelio 1-MNA and save 10% click here and code NAT10 will be entered for you at checkout. 
 
Episode Timestamps:
Welcome and introduction to Longevity Podcast ... 00:00:00
Challenging beliefs about aging and cellular health ... 00:12:00
Deep dive into NAD+ biochemistry and cellular function ... 00:13:08
NAD+/NADH balance: Why both matter ... 00:15:24
Why NAD+ declines: Not just aging, but increased degradation ...00:18:26
The role of CD38 and NMNT enzymes in NAD metabolism ... 00:20:14
Controversy and confusion: NAD+ precursors (NR, NMN) and IVs ... 00:22:28
Methylation's hidden importance in NAD supplementation ... 00:30:55
Supplementing 1-MNA: Understanding dosages and applications ... 00:50:54
Assessing NAD+ status: Biomarkers and limitations of testing ... 00:53:01
Lifestyle ROI: Sleep, exercise, and circadian rhythm for NAD preservation ... 00:57:14
Ketones: Beyond performance, supporting cellular energy and longevity ... 01:06:03
Future of NAD science: Anticipating new insights and risks ... 01:11:45
Confidence and humility: Advice for navigating the longevity field ... 01:18:52
 
Our Amazing Sponsors:
Qualia Creatine+ by Qualia Life – A clinically formulated blend of two highly bioavailable forms of creatine plus magnesium and electrolytes to support lean muscle, cellular energy, and brain health—especially for women over 40 who naturally produce less with age. Go to qualialife.com/nathalie and use code NATHALIE to save up to 50%, plus an additional 15% off.
 
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Dr. Bill Lawrence Episode

Today, I'm joined by the innovative Dr. Cynthia Keller, a pediatrician whose passion for integrative and functional medicine has reshaped how we understand post-COVID health challenges. Dr. Keller opens up about her journey from conventional medicine to designing unique solutions for children and families, revealing how her care, presence, and determination to "solve the unsolvable" led to breakthroughs in treating mood changes, weight gain, and energy loss after COVID.
Special Offer:
If you go to  alchemicmedicinals.com and use code NatRocks at checkout, you'll get a whopping 50% off of the Tryptophan Re-Genesis™ Powder while supplies last! (Capsules not included).


Episode Timestamps:
Introduction and host's mission ... 00:00:00
From standard care to integrative pediatrics ... 00:05:05
Patterns in pediatric development and disease ... 00:09:19
Gut health, emotional factors, and parenting ... 00:10:44
Clinic model and multidisciplinary care ... 00:15:04
Post-COVID nutrient depletion: clinical discoveries ... 00:18:03
Key depleted cofactors and rapid recovery ... 00:19:31
COVID's ongoing impact on gut and microbiome ... 00:24:39
Grassroots collaboration and evolving strategies ... 00:26:28
Clinical patterns: mood, weight, thirst ... 00:36:02
Family-wide interventions and quick results ... 00:46:24
Symptoms-based approach, minimal testing ... 00:52:07
Supplementation protocol and cautions ... 00:57:14
Product development and access ... 01:08:22
Infant microbiome and generational shifts ... 01:10:28
Pediatricians: importance of listening and presence ... 01:20:09
Love and connection in clinical care ... 01:21:01
Modern dysregulation: loss of boredom ... 01:22:28
 
Our Amazing Sponsors:
Ozlo - use smart sound engineering and sleep detection to help you stay in deeper, more stable sleep all night. Create your ideal sleep environment anywhere: go to ozlosleep.com/nat and use code NAT to get $75 off.
 
Youth Daily by Young Goose — An all-in-one moisturizer powered by NAD+ nano precursors to boost elasticity, smooth wrinkles, and keep your skin looking fresh, dewy, and full of life; grab yours at younggoose.com and use code Nat10 for first orders or this link and code 5NAT for returning customers.
 
Mitopure Longevity Gummies by Timeline — Clinically backed Urolithin A supports mitochondrial health to boost energy, recovery, and healthy aging, all in an easy daily gummy instead of another pill; go to timeline.com/nat20 for 20% off Mitopure Gummies.
 
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Dr. Bill Lawrence Episode